Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system

2019 ◽  
Vol 26 (6) ◽  
pp. 5645-5657 ◽  
Author(s):  
Shahbaz Ahmad ◽  
Riaz Mahmood
Keyword(s):  
Plasma Membrane ◽  
Redox System ◽  
Human Erythrocytes ◽  
Mercury Chloride ◽  
Antioxidant Power ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox ◽  
Hemoglobin Oxidation ◽  
Chloride Toxicity

Red wine activates plasma membrane redox system in human erythrocytes

2016 ◽  
Vol 50 (5) ◽  
pp. 557-569 ◽  
Author(s):  
Idolo Tedesco ◽  
Stefania Moccia ◽  
Silvestro Volpe ◽  
Giovanna Alfieri ◽  
Daniela Strollo ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Red Wine ◽  
Redox System ◽  
Human Erythrocytes ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox

A link between transport and plasma membrane redox system(s) in carrot cells

1984 ◽  
Vol 16 (2) ◽  
pp. 143-152 ◽  
Author(s):  
Prakash C. Misra ◽  
Theodore A. Craig ◽  
Frederick L. Crane
Keyword(s):  
Plasma Membrane ◽  
Redox System ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox ◽  
Carrot Cells

scholarly journals Plasma membrane redox system protects cells against oxidative stress

Redox Report ◽  
2000 ◽  
Vol 5 (2-3) ◽  
pp. 148-150 ◽  
Author(s):  
J.C. Rodríguez-Aguilera ◽  
G. López-Lluch ◽  
C. Santos-Ocaña ◽  
J.M. Villalba ◽  
C. Gómez-Díaz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Plasma Membrane ◽  
Redox System ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox

Erythrocyte Plasma Membrane Redox System in Human Aging

2006 ◽  
Vol 9 (4) ◽  
pp. 470-474 ◽  
Author(s):  
Syed Ibrahim Rizvi ◽  
Rashmi Jha ◽  
Pawan Kumar Maurya
Keyword(s):  
Plasma Membrane ◽  
Redox System ◽  
Human Aging ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox ◽  
Erythrocyte Plasma Membrane

Ehrlich cell plasma membrane redox system is modulated through signal transduction pathways involvingcGMP and Ca2+ as second messengers

1995 ◽  
Vol 27 (6) ◽  
pp. 605-611 ◽  
Author(s):  
Antonio del Castillo-Olivares ◽  
Alicia Esteban del Valle ◽  
Javier Márquez ◽  
Ignacio NÚñez de Castro ◽  
Miguel ángel Medina
Keyword(s):  
Signal Transduction ◽  
Plasma Membrane ◽  
Second Messengers ◽  
Redox System ◽  
Signal Transduction Pathways ◽  
Cell Plasma Membrane ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox ◽  
Ehrlich Cell ◽  
Cell Plasma

scholarly journals Properties and regulation of a trans-plasma membrane redox system in rat liver

1982 ◽  
Vol 204 (3) ◽  
pp. 795-801 ◽  
Author(s):  
Michael G. Clark ◽  
Eric J. Partick ◽  
Frederick L. Crane
Keyword(s):  
Plasma Membrane ◽  
Cyclic Amp ◽  
Rat Liver ◽  
Redox System ◽  
Isolated Perfused Rat Liver ◽  
Ferricyanide Reduction ◽  
Plasma Membrane Redox System ◽  
Glucose Release ◽  
Plasma Membrane Redox ◽  
Ph Values

1. Regulation of the reduction of ferricyanide by the isolated perfused rat liver was studied. 2. The rate of reduction was dependent on the rate of supply of ferricyanide and independent of perfusate oxygen concentration. 3. The effect of pH was also examined; the rate of reduction was optimal at pH 7.4 and was inhibited to a greater extent by pH values below 7.4 than those above 7.4. 4. The effects of substrates on the rate of ferricyanide reduction was assessed. Reductants of the cytosolic and mitochondrial NADH/NAD+ couple were tested. 2-Hydroxybutyrate (10mm), lactate (10mm), glycerol (10mm) and ethanol (10mm) each had no effect. Dihydroxyacetone (10mm) stimulated the rate. 5. Dehydroascorbate (1mm), stimulated the rate of ferricyanide reduction; the stimulation did not appear to be attributable to the production of reduced substances that were excreted to reduce extracellular ferricyanide. 6. The effects of glucagon and cyclic AMP on the rate of ferricyanide reduction were examined. Glucagon inhibited the rate by approx. 30% and half-maximal inhibition occurred at 0.1 nm, corresponding to the concentration at which half-maximal stimulation of glucose release occurred. Cyclic AMP stimulated glucose release but had no significant effect on the rate of ferricyanide reduction. It is concluded that the trans-plasma membrane redox system of liver that reduces extracellular ferricyanide is regulated by glucagon. The rate is also altered by the substrate dihydroxyacetone. The effect of glucagon may be direct as it cannot be mimicked by cyclic AMP and it occurs directly following exposure to the hormone.

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