Sodium nitrite enhances generation of reactive oxygen species that decrease antioxidant power and inhibit plasma membrane redox system of human erythrocytes

2016 ◽  
Vol 40 (8) ◽  
pp. 887-894 ◽  
Author(s):  
Fariheen Aisha Ansari ◽  
Riaz Mahmood
Keyword(s):  
Reactive Oxygen Species ◽  
Plasma Membrane ◽  
Sodium Nitrite ◽  
Reactive Oxygen ◽  
Redox System ◽  
Human Erythrocytes ◽  
Oxygen Species ◽  
Antioxidant Power ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox

Red wine activates plasma membrane redox system in human erythrocytes

2016 ◽  
Vol 50 (5) ◽  
pp. 557-569 ◽  
Author(s):  
Idolo Tedesco ◽  
Stefania Moccia ◽  
Silvestro Volpe ◽  
Giovanna Alfieri ◽  
Daniela Strollo ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Red Wine ◽  
Redox System ◽  
Human Erythrocytes ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox

Hexavalent chromium induces reactive oxygen species and impairs the antioxidant power of human erythrocytes and lymphocytes: Decreased metal reducing and free radical quenching ability of the cells

2017 ◽  
Vol 33 (8) ◽  
pp. 623-635 ◽  
Author(s):  
Nazim Husain ◽  
Riaz Mahmood
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Free Radicals ◽  
Free Radical ◽  
Hexavalent Chromium ◽  
Reactive Oxygen ◽  
Human Erythrocytes ◽  
Cellular Damage ◽  
Oxygen Species ◽  
Antioxidant Power

The toxicity of hexavalent chromium [Cr(VI)] in biological systems is thought to be closely associated with the generation of free radicals and reactive oxygen species. These species are produced when Cr(VI) is reduced to its trivalent form in the cell. This process results in oxidative stress due to an imbalance between the detoxifying ability of the cell and the production of free radicals. We have studied the effect of potassium dichromate (K2Cr2O7), a [Cr(VI)] compound, on the antioxidant power of human erythrocytes and lymphocytes under in vitro conditions. Incubation of erythrocytes and lymphocytes with different concentrations of K2Cr2O7 resulted in a marked dose-dependent decrease in reduced glutathione and an increase in oxidized glutathione and reactive oxygen species levels. The antioxidant power of the cells was decreased, as determined by metal reducing and free radical quenching assays. These results show that [Cr(VI)] upregulates the generation of reactive oxygen species and, as a consequence, the cellular antioxidant defences are compromised. The resulting oxidative stress may contribute to Cr(VI)-induced cellular damage.

The plasma membrane redox system in human platelet functions and platelet-leukocyte interactions

2009 ◽  
Vol 101 (02) ◽  
pp. 284-289 ◽  
Author(s):  
Gianluca Frega ◽  
Isabella Savini ◽  
Valeria Catani ◽  
Antonello Rossi ◽  
Luciana Avigliano ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Redox Reactions ◽  
Human Platelet ◽  
Redox System ◽  
Oxygen Species ◽  
Plasma Membrane Redox System ◽  
Plasma Membrane Redox ◽  
Radical Production ◽  
Plasma Membrane Electron Transport ◽  
Platelet Functions

SummaryThe plasma membrane electron transport is crucial for blood coagulation and thrombosis, since reactive oxygen species and thiol changes, generated by plasma membrane redox reactions, modulate activation of platelets, as well as their interaction with leukocytes. Several antioxidants are linked to this system; thus, platelets are also able to counterbalance radical production and to regulate thrombus growth. Aim of this review is to give an update on the plasma membrane redox system in platelets, as well as on its role in platelet functions and leukocyte-platelet crosstalk.

Reactive oxygen species produced via plasma membrane NADPH oxidase regulate anthocyanin synthesis in apple peel

Planta ◽  
2014 ◽  
Vol 240 (5) ◽  
pp. 1023-1035 ◽  
Author(s):  
Jiangli Zhang ◽  
Changsheng Chen ◽  
Di Zhang ◽  
Houhua Li ◽  
Pengmin Li ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Plasma Membrane ◽  
Nadph Oxidase ◽  
Reactive Oxygen ◽  
Anthocyanin Synthesis ◽  
Oxygen Species ◽  
Apple Peel
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