Investigating dynamic susceptibility contrast-enhanced perfusion-weighted magnetic resonance imaging in posterior fossa tumors: differences and similarities with supratentorial tumors

2020 ◽  
Vol 125 (4) ◽  
pp. 416-422 ◽  
Author(s):  
Simona Gaudino ◽  
Massimo Benenati ◽  
Matia Martucci ◽  
Annibale Botto ◽  
Amato Infante ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Dynamic Susceptibility ◽  
Resonance Imaging ◽  
Dynamic Susceptibility Contrast ◽  
Posterior Fossa Tumors ◽  
Contrast Enhanced ◽  
Weighted Magnetic Resonance Imaging ◽  
Susceptibility Contrast ◽  
Supratentorial Tumors

scholarly journals Diagnostic Value of Semiquantitative Analysis of Dynamic Susceptibility Contrast Magnetic Resonance Imaging with GD-EOB-DTPA in Focal Liver Lesions Characterization: A Feasibility Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Davide Ippolito ◽  
Maddalena Colombo ◽  
Chiara Trattenero ◽  
Pietro Andrea Bonaffini ◽  
Cammillo Talei Franzesi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Focal Liver Lesions ◽  
Dynamic Susceptibility ◽  
Liver Lesions ◽  
Resonance Imaging ◽  
Dynamic Susceptibility Contrast ◽  
Contrast Enhanced ◽  
Malignant Lesions ◽  
Susceptibility Contrast

Purpose.To assess the diagnostic accuracy of dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSCE-MRI) in differentiation between benign and malignant liver lesions by assessment of tumoral perfusion parameters.Methods Materials.Seventy-three patients with known focal liver lesions, including 45 benign (16 FNH, 27 angiomas, and 2 abscesses) and 28 malignant ones (17 metastases, 9 HCCs, and 2 cholangiocarcinoma) underwent 1.5 T MRI upper abdominal study, with standard protocol that included dynamic contrast-enhanced sequences. On dedicated workstation, time-intensity curves were determined and the following perfusion parameters were calculated: relative arterial, venous and late enhancement (RAE, RVE, RLE), maximum enhancement (ME), relative enhancement (RE), and time to peak (TTP).Results.All diagnoses were established either by histopathology or imaging follow-up. Perfusion mean values calculated in benign lesions were RAE 33.8%, RVE 66.03%, RLE 80.63%, ME 776.00%, MRE 86.27%, and TTP 146.95 sec. Corresponding perfusion values calculated in malignant lesions were RAE 22.47%, RVE 40.54%, RLE 47.52%, ME 448.78%, MRE 49.85%, and TTP 183.79 sec. Statistical difference (p<0.05) was achieved in all the perfusion parameters calculated, obtaining different cluster of perfusion kinetics between benign and malignant lesions.Conclusions.DSCE-MRI depicts kinetic differences in perfusion parameters among the different common liver lesions, related to tumour supply and microvascular characteristics.

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