Effect of CD4+ T-lymphocyte count on hospital outcome of elective general thoracic surgery patients with human immunodeficiency virus

2011 ◽  
Vol 59 (11) ◽  
pp. 743-747 ◽  
Author(s):  
Satoshi Nagasaka ◽  
Hirohisa Yazaki ◽  
Hideyuki Ito ◽  
Shin-ichi Oka ◽  
Hiromi Kuwata ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Thoracic Surgery ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Hospital Outcome ◽  
Immunodeficiency Virus ◽  
General Thoracic Surgery

scholarly journals Thyroid dysfunction in human immunodeficiency virus-infected children and its correlation with CD4+T lymphocyte count

2015 ◽  
Vol 19 (2) ◽  
pp. 272 ◽  
Author(s):  
Salam Ranabir ◽  
Satyakumar Thongam ◽  
Sunibala Keithelakpam ◽  
TombaY Singh ◽  
RanbirL Singh ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Thyroid Dysfunction ◽  
Immunodeficiency Virus

Uveitis in human immunodeficiency virus-infected persons with CD4+ T-lymphocyte count over 200 cells/mL

2013 ◽  
Vol 42 (2) ◽  
pp. 118-125 ◽  
Author(s):  
Jennifer Rose-Nussbaumer ◽  
Debra A Goldstein ◽  
Jennifer E Thorne ◽  
Tiago E Arantes ◽  
Nisha R Acharya ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Immunodeficiency Virus

scholarly journals Cutaneous Anergy in Pregnant and Nonpregnant Women With Human Immunodeficiency Virus

1998 ◽  
Vol 6 (1) ◽  
pp. 13-17 ◽  
Author(s):  
N. L. Eriksen ◽  
A. W. Helfgott
Keyword(s):  
Human Immunodeficiency Virus ◽  
Skin Test ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Skin Testing ◽  
The Other ◽  
Tuberculin Skin Testing ◽  
Test Results ◽  
Significant Difference ◽  
Immunodeficiency Virus

Objective:To determine the prevalence of cutaneous anergy in pregnant and nonpregnant women who are seropositive for human immunodeficiency virus.Methods and materials:The medical records of 159 women seropositive for human immunodeficiency virus were reviewed. Demographic characteristics and tuberculin skin test results were abstracted from the chart. Tuberculin skin testing was performed by the Mantoux method (5 tuberculin units of purified protein derivative injected intradermally). Anergy testing was performed using any two of the three following antigens; tetanus toxoid, mumps, orCandidaskin test antigen. A positive tuberculin test was defined as induration of 5 mm or more, and a positive test for the other antigens was defined as any amount of induration over the skin test area. Anergy was defined as any amount of induration to the other antigens. A CD4+T lymphocyte count was obtained at the time of skin testing. Continuous variables were analyzed using the Mann Whitney—U test. Categorical data were analyzed with the chi-square or Fisher's exact test as appropriate. A two-tailedPvalue <0.05 was considered significant.Results:There were 102 nonpregnant and 57 pregnant women who returned to have their skin test results read. There was no significant difference in the prevalence of positive, negative or anergic skin test results between groups. The CD4+T lymphocyte count (mean ± standard deviation) in patients with anergic results was similar between pregnant (375 ± 256/mm3) and nonpregnant (358 ± 305/mm3) women (P= 0.64).Conclusion:The prevalence of cutaneous anergy is similar among pregnant and nonpregnant women seropositive for human immunodeficiency virus.

scholarly journals Values of Lymphocyte Subsets in Nepalese Healthy Adult Population

2012 ◽  
Vol 52 (185) ◽  
Author(s):  
G Shakya ◽  
S P Dumre ◽  
S Malla ◽  
M Sharma ◽  
K P KC ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Lymphocytes ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Lymphocyte Subsets ◽  
Healthy Adult ◽  
Adult Population ◽  
Reference Ranges ◽  
Immunodeficiency Virus ◽  
Central Eastern

Introduction: CD4 T lymphocyte is the most commonly used cellular marker in tracking Human Immunodeficiency Virus (HIV) infection progression and monitoring effect of antiretroviral therapy (ART). Due to lack of local reference values of CD4 and other T lymphocytes in Nepal, most clinical decisions are based on the reference renges of western countries.  Methods: This study was conducted at three major hospitals/laboratory of central, eastern and western Nepal during November 2008 through July 2009. Using the predefined criteria, 602 (200, 202 and 200 from central, eastern and western regions respectively) healthy adult volunteers of age range 18-60 years were recruited wiht equal representation from each age group and sex. Blood specimens were screened for HIV following standard algorithm using ELISA and two rapid test kits based on different principles. Samples with discordant test-results were excluded. HIV sero-negative specimens were further analyzed for CD4, CD8 and CD4:CD8 ratio, and absolute lymphocyte count (ALC) by FACS count (Becton Dickinson, USA) and automated cell counter (BC-3000 Plus, Shenzhen Mindray Biomedical Electronics, Germany) respectively. Results: The average value (mean± standard deviation) of CD4, CD8, CD4/CD8 ratio and ALC of Nepalese adult population were found to be 786 ± 248, 567±230, 1.52 ± 0.59 and 2712 ± 836 respectively. All four parameters but CD8 were significantly different with sex and females had relatively higher values. However, none of these parameters reported significant difference with age except the ALC. Conclusions: Nepalese healthy adult populations have significantly different T lymphocyte subsets compared to other countries. The present reference ranges of CD4 and other T lymphocytes may be used for any clinical purposes including classifying and monitoring disease status in HIV infected individuals, immune status evaluation, monitoring ART and accordingly making amendment in national HIV treatment guidelines in Nepal. Keywords:Absolute lymphocyte count, CD4, CD8, human immunodeficiency virus, T lymphocytes.

scholarly journals Evaluation of a New Single-Parameter Volumetric Flow Cytometer (CyFlowgreen) for Enumeration of Absolute CD4+ T Lymphocytes in Human Immunodeficiency Virus Type 1-Infected Thai Patients

2005 ◽  
Vol 12 (12) ◽  
pp. 1416-1424 ◽  
Author(s):  
Kovit Pattanapanyasat ◽  
Surada Lerdwana ◽  
Egarit Noulsri ◽  
Thanyanan Chaowanachan ◽  
Punneeporn Wasinrapee ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
T Lymphocyte ◽  
Flow Cytometer ◽  
Single Parameter ◽  
Becton Dickinson ◽  
Flow Cytometric Method ◽  
Immunodeficiency Virus

ABSTRACT Use of the standard dual-platform flow cytometric method for determination of CD4+ T-lymphocyte counts, which needs both a flow cytometer (FCM) and hematological analyzer, would inevitably lead to increased variability. The development of new single-platform (SP) FCMs that provide direct CD4+ T-lymphocyte counts for improved assay precision and accuracy have recently attracted attention. This study evaluated one of those systems, CyFlowgreen (Partec), a single-parameter SP volumetric FCM. The performance of CyFlowgreen was compared with those of two reference standard SP microbead-based technologies of the three-color TruCOUNT tube with the FACScan FCM and a two-color FACSCount system (Becton Dickinson Biosciences). Absolute CD4+ and CD8+ T-lymphocyte counts in 200 human immunodeficiency virus type 1-seropositive blood specimens were determined. Statistical analysis for correlation and agreement were performed. A high correlation of absolute CD4 counts was shown when those obtained with CyFlowgreen were compared with those obtained with the bead-based three-color TruCOUNT system (R 2 = 0.96; mean bias, −69.1 cells/μl; 95% confidence interval [CI], −225.7 to +87.5 cells/μl) and the FACSCount system (R 2 = 0.97; mean bias, −40.0 cells/μl; 95% CI, −165.1 to +85.1 cells/μl). The correlation of the CD4+ T-lymphocyte counts obtained by the two bead-based systems was high (R 2 = 0.98). Interestingly, CyFlowgreen yielded CD4+ T-lymphocyte counts that were 21.8 and 7.2 cells/μl lower than those obtained with the TruCOUNT and the FACSCount systems, respectively, when CD4+ T-lymphocyte counts were <250 CD4+ T-lymphocyte counts/μl range or 17.3 and 5.8 cells/μl less, respectively, when CD4+ T-lymphocyte counts were <200 cells/μl. The single-parameter CyFlowgreen volumetric technology performed well in comparison with the performance of the standard SP bead-based FCM system. However, a multicenter comparative study is needed before this FCM machine is implemented in resource-limited settings.

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