Rethinking Bile Acid Metabolism and Signaling for Type 2 Diabetes Treatment

2018 ◽  
Vol 18 (11) ◽  
Author(s):  
Karolina E. Zaborska ◽  
Bethany P. Cummings
Keyword(s):  
Type 2 Diabetes ◽  
Bile Acid ◽  
Acid Metabolism ◽  
Bile Acid Metabolism ◽  
Diabetes Treatment ◽  
Type 2 Diabetes Treatment

scholarly journals Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

Hepatology ◽  
2010 ◽  
Vol 52 (4) ◽  
pp. 1455-1464 ◽  
Author(s):  
Gemma Brufau ◽  
Frans Stellaard ◽  
Kris Prado ◽  
Vincent W. Bloks ◽  
Elles Jonkers ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Bile Acid ◽  
Glycemic Control ◽  
Acid Metabolism ◽  
Bile Acid Metabolism

scholarly journals Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

2011 ◽  
Vol 11 (3) ◽  
pp. 160-166 ◽  
Author(s):  
Janne Prawitt ◽  
Sandrine Caron ◽  
Bart Staels
Keyword(s):  
Type 2 Diabetes ◽  
Bile Acid ◽  
Acid Metabolism ◽  
Bile Acid Metabolism

scholarly journals Carbohydrate digestive enzymes are inhibited by Poincianella pluviosa stem bark extract: relevance on type 2 diabetes treatment

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Camila Gabriel Kato-Schwartz ◽  
Anacharis Babeto de Sá-Nakanishi ◽  
Ana Carolina Guidi ◽  
Geferson de Almeida Gonçalves ◽  
Fernanda Giacomini Bueno ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Digestive Enzymes ◽  
Stem Bark ◽  
Bark Extract ◽  
Diabetes Treatment ◽  
Type 2 Diabetes Treatment ◽  
Stem Bark Extract

scholarly journals Type 2 Diabetes Treatment and Drug Development Study

2018 ◽  
Vol 8 (1) ◽  
pp. 22-33 ◽  
Author(s):  
Da-Yong Lu ◽  
Jin-Yu Che ◽  
Nagendra Sastry Yarla ◽  
Hong-Ying Wu ◽  
Ting-Ren Lu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Drug Targets ◽  
Medical Knowledge ◽  
Modern Medicine ◽  
Diabetes Treatment ◽  
Candidate Drug ◽  
The Future ◽  
Type 2 Diabetes Treatment ◽  
And Personalized Medicine

The causality and etio-pathologic risks for patients with Type 2 Diabetes (T2DM) are important areas in modern medicine. Disease complications are largely unpredictable in patients with T2DM. In the future, we welcome therapeutics of both cutting-edge and traditional for anti-diabetic treatments and management with higher efficiency and less cost. Expanding medical knowledge, behavior/life-style notification in healthcare, modern genetic/bioinformatics diagnostic promotion, clinical developments (Traditional Chinese Medicine and personalized medicine) and new drug developments - including candidate drug targets should be implemented in the future. These efforts might be useful avenues for updating anti-diabetic therapeutics globally. This article aims at introducing this information for T2DM treatment boosts.

Effects of Diet on Bile Acid Metabolism and Insulin Resistance in Type 2 Diabetic Rats after Roux-en-Y Gastric Bypass

2018 ◽  
Vol 28 (10) ◽  
pp. 3044-3053 ◽  
Author(s):  
Cheng-Xiang Shan ◽  
Nian-Cun Qiu ◽  
Miao-E Liu ◽  
Si-Luo Zha ◽  
Xin Song ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Gastric Bypass ◽  
Bile Acid ◽  
Acid Metabolism ◽  
Diabetic Rats ◽  
Bile Acid Metabolism ◽  
Type 2 Diabetic

Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment

2019 ◽  
Vol 27 (2) ◽  
pp. 394-409 ◽  
Author(s):  
Shoichi Kuroda ◽  
Yohei Kobashi ◽  
Takahiro Oi ◽  
Kenichi Kawabe ◽  
Fumiyasu Shiozawa ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetes Treatment ◽  
Sodium Dependent ◽  
Type 2 Diabetes Treatment

scholarly journals Hsp72 (HSPA1A) Prevents Human Islet Amyloid Polypeptide Aggregation and Toxicity: A New Approach for Type 2 Diabetes Treatment

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0149409 ◽  
Author(s):  
Paola C. Rosas ◽  
Ganachari M. Nagaraja ◽  
Punit Kaur ◽  
Alexander Panossian ◽  
Georg Wickman ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Diabetes Treatment ◽  
Islet Amyloid ◽  
New Approach ◽  
Human Islet Amyloid Polypeptide ◽  
Type 2 Diabetes Treatment
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