Ultrasound-Assisted Emulsification of Roasted Coffee Oil in Complex Coacervates and Real-time Coffee Aroma Release by PTR-ToF–MS

2021 ◽  
Author(s):  
Rodolfo Campos Zanin ◽  
Samo Smrke ◽  
Chahan Yeretzian ◽  
Louise Emy Kurozawa ◽  
Fabio Yamashita
Keyword(s):  
Real Time ◽  
Roasted Coffee ◽  
Aroma Release ◽  
Ultrasound Assisted ◽  
Coffee Oil ◽  
Tof Ms

The role of ultrasound-assisted emulsification of roasted coffee oil on aroma profile in spray-dried microparticles and its dynamic release by PTR-ToF–MS

2021 ◽  
Vol 247 (4) ◽  
pp. 865-878
Author(s):  
Rodolfo Campos Zanin ◽  
Marcelo Caldeira Viegas ◽  
Samo Smrke ◽  
Chahan Yeretzian ◽  
Louise Emy Kurozawa ◽  
...  
Keyword(s):  
Roasted Coffee ◽  
Aroma Profile ◽  
Ultrasound Assisted ◽  
Coffee Oil ◽  
Spray Dried ◽  
Tof Ms

Modulation of aroma release of instant coffees through microparticles of roasted coffee oil

2021 ◽  
Vol 341 ◽  
pp. 128193 ◽  
Author(s):  
Rodolfo Campos Zanin ◽  
Samo Smrke ◽  
Louise Emy Kurozawa ◽  
Fabio Yamashita ◽  
Chahan Yeretzian
Keyword(s):  
Roasted Coffee ◽  
Aroma Release ◽  
Coffee Oil

scholarly journals Effect of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) Alone versus MALDI-TOF MS Combined with Real-Time Antimicrobial Stewardship Interventions on Time to Optimal Antimicrobial Therapy in Patients with Positive Blood Cultures

2017 ◽  
Vol 55 (5) ◽  
pp. 1437-1445 ◽  
Author(s):  
Maya Beganovic ◽  
Michael Costello ◽  
Sarah M. Wieczorkiewicz
Keyword(s):  
Real Time ◽  
Laser Desorption ◽  
Blood Cultures ◽  
Laser Desorption Ionization ◽  
Ionization Time ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Flight Mass Spectrometry ◽  
Tof Ms ◽  
Matrix Assisted Laser

ABSTRACT Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) decreases the time to organism identification and improves clinical and financial outcomes. The purpose of this study was to evaluate the impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time, pharmacist-driven, antimicrobial stewardship (AMS) intervention on patient outcomes. This single-center, pre-post, quasiexperimental study evaluated hospitalized patients with positive blood cultures identified via MALDI-TOF MS combined with prospective AMS intervention compared to a control cohort with MALDI-TOF MS identification without AMS intervention. AMS intervention included: real-time MALDI-TOF MS pharmacist notification and prospective AMS provider feedback. The primary outcome was the time to optimal therapy (TTOT). A total of 252 blood cultures, 126 in each group, were included in the final analysis. MALDI-TOF MS plus AMS intervention significantly reduced the overall TTOT (75.17 versus 43.06 h; P < 0.001), the Gram-positive contaminant TTOT (48.21 versus 11.75 h; P < 0.001), the Gram-negative infection (GNI) TTOT (71.83 versus 35.98 h; P < 0.001), and the overall hospital length of stay (LOS; 15.03 versus 9.02 days; P = 0.021). The TTOT for Gram-positive infection (GPI) was improved (64.04 versus 41.61 h; P = 0.082). For GPI, the hospital LOS (14.64 versus 10.31 days; P = 0.002) and length of antimicrobial therapy 24.30 versus 18.97 days; P = 0.018) were reduced. For GNI, the time to microbiologic clearance (51.13 versus 34.51 h; P < 0.001), the hospital LOS (15.40 versus 7.90 days; P = 0.027), and the intensive care unit LOS (5.55 versus 1.19 days; P = 0.035) were reduced. To achieve optimal outcomes, rapid identification with MALDI-TOF MS combined with real-time AMS intervention is more impactful than MALDI-TOF MS alone.

scholarly journals Ultrasound-assisted photothermal therapy and real-time treatment monitoring

2018 ◽  
Vol 9 (9) ◽  
pp. 4472 ◽  
Author(s):  
Haemin Kim ◽  
Gyuwon Jo ◽  
Jin Ho Chang
Keyword(s):  
Real Time ◽  
Photothermal Therapy ◽  
Treatment Monitoring ◽  
Time Treatment ◽  
Ultrasound Assisted

scholarly journals Comprehensive Data Scientific Procedure for Enhanced Analysis and Interpretation of Real-Time Breath Measurements in In Vivo Aroma-Release Studies

2015 ◽  
Vol 87 (20) ◽  
pp. 10338-10345 ◽  
Author(s):  
Ewa Szymańska ◽  
Phil A. Brown ◽  
Aldo Ziere ◽  
Sara Martins ◽  
Max Batenburg ◽  
...  
Keyword(s):  
Real Time ◽  
Aroma Release ◽  
Comprehensive Data ◽  
Release Studies

scholarly journals Effects of modular ion-funnel technology onto analysis of breath VOCs by means of real-time mass spectrometry

2020 ◽  
Vol 412 (26) ◽  
pp. 7131-7140
Author(s):  
Giovanni Pugliese ◽  
Felix Piel ◽  
Phillip Trefz ◽  
Philipp Sulzer ◽  
Jochen K. Schubert ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Human Subjects ◽  
Proton Transfer Reaction ◽  
Mass Analyzer ◽  
Real Time Monitoring ◽  
Healthy Human ◽  
Flight Mass Spectrometry ◽  
Ion Funnel ◽  
Tof Ms

Abstract Proton transfer reaction time-of-flight mass spectrometry (PTR-ToF-MS) is a powerful tool for real-time monitoring of trace concentrations of volatile organic compounds (VOCs). The sensitivity of PTR-ToF-MS also depends on the ability to effectively focus and transmit ions from the relatively high-pressure drift tube (DT) to the low-pressure mass analyzer. In the present study, a modular ion-funnel (IF) is placed adjacent to the DT of a PTR-ToF-MS instrument to improve the ion-focusing. IF consists of a series of electrodes with gradually decreasing orifice diameters. Radio frequency (RF) voltage and direct current (DC) electric field are then applied to the electrodes to get the ions focused. We investigated the effect of the RF voltage and DC field on the sensitivity of a pattern of VOCs including hydrocarbons, alcohols, aldehydes, ketones, and aromatic compounds. In a proof-of-concept study, the instrument operating both as normal DT (DC-mode) and at optimal IF conditions (RF-mode) was applied for the breath analysis of 21 healthy human subjects. For the range of investigated VOCs, an improvement of one order of magnitude in sensitivity was observed in RF-mode compared with DC-mode. Limits of detection could be improved by a factor of 2–4 in RF-mode compared with DC-mode. Operating the instrument in RF-mode allowed the detection of more compounds in the exhaled air compared with DC-mode. Incorporation of the IF considerably improved the performance of PTR-ToF-MS allowing the real-time monitoring of a larger number of potential breath biomarkers.

scholarly journals Brazilian roasted coffee oil obtained by mechanical expelling: compositional analysis by GC-MS

2005 ◽  
Vol 25 (4) ◽  
pp. 677-682 ◽  
Author(s):  
Alessandra L. de Oliveira ◽  
Paulo Marcio Cruz ◽  
Marcos N. Eberlin ◽  
Fernando A. Cabral
Keyword(s):  
Compositional Analysis ◽  
Roasted Coffee ◽  
Coffee Oil

Simultaneous Real-Time Measurements of Mastication, Swallowing, Nasal Airflow, and Aroma Release

2003 ◽  
Vol 51 (17) ◽  
pp. 5052-5057 ◽  
Author(s):  
M. Hodgson ◽  
R. S. T. Linforth ◽  
A. J. Taylor
Keyword(s):  
Real Time ◽  
Nasal Airflow ◽  
Aroma Release
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