Regression of cytomegalovirus retinitis after decreased doses of immunosuppressive agents in a renal transplant recipient

2000 ◽  
Vol 32 (4) ◽  
pp. 325-327
Author(s):  
Yoriko Hayasaka ◽  
Seiji Hayasaka ◽  
Konomi Watanabe ◽  
Akihiro Futamura
2012 ◽  
Vol 45 (2) ◽  
pp. 581-585 ◽  
Author(s):  
Mohan P. Patel ◽  
Vivek B. Kute ◽  
Manoj R. Gumber ◽  
Pankaj R. Shah ◽  
Himanshu V. Patel ◽  
...  

2012 ◽  
Vol 2 (1) ◽  
pp. 63-65 ◽  
Author(s):  
Md Tariful Hoque ◽  
Palash Mitra ◽  
Tasrina Shamnaz Samdani ◽  
Golzar Hossain ◽  
Zainal Abedin ◽  
...  

Acute tubular necrosis (ATN) is a medical condition involving damage of the tubular cells of the nephron following a toxic or ischaemic injury. If the cause of ATN is removed then recovery is likely. Calcineurin inhibitors (ciclosporin & tacrolimus) are used as immunosuppressive agents in renal transplant recipient. But either of these two drugs can cause acute nephrotoxicity. A 62 years old known diabetic, hypertensive & ESRD patient after undergoing living related donor renal transplantation started passing significant amount of urine, but 12 hrs after transplantation the amount of urine output started to decrease and the patient became anuric after 17hrs of transplantation. Immediately the patient was evaluated thoroughly and calcineurin inhibitor (tacrolimus) was witheld. The patient again started passing urine from 4th POD. DOI: http://dx.doi.org/10.3329/birdem.v2i1.12365 Birdem Med J 2012; 2(1) 63-65


2020 ◽  
Vol 10 (6) ◽  
pp. 470-475 ◽  
Author(s):  
Lan Zhu ◽  
Hongge Shu ◽  
Huijun Li ◽  
Tao Qiu ◽  
Jiangqiao Zhou ◽  
...  

With the global spread of SARS-Cov-2 infections, increasing numbers of COVID-19 cases have been reported in transplant recipients. However, reports are lacking concerning the treatment and prognosis of COVID-19 pneumonia in renal transplant recipients with acute cardiorenal syndrome. We report here the complete clinical course of a renal transplant recipient with critical COVID-19 pneumonia. In the early phase of SARS-Cov-2 infection, the patient exhibited extensive lung lesions and significant acute kidney and heart injuries, which required treatment in the ICU. After correcting the arrhythmia and heart failure, the patient recovered quickly from the acute kidney injury with a treatment of intensive diuresis and strict control of fluid intake. Without cessation of oral immunosuppressive agents, the patient presented a delayed and low antibody response against SARS-Cov-2 and reappeared positive for the virus twice after being discharged. Nevertheless, the patient’s pneumonia continued to improve and he fully recovered in 69 days. This effectively treated case may be meaningful and referable for the treatment of COVID-19 pneumonia in other transplant recipients with acute cardiorenal syndrome.


2021 ◽  
Vol 9 ◽  
pp. 86-89
Author(s):  
Alan Snyder ◽  
Ahmad Aleisa ◽  
Jessica Lewis ◽  
Joni Mazza-McCrann ◽  
Jessica A. Forcucci

1984 ◽  
Vol 141 (4) ◽  
pp. 241-242
Author(s):  
David C. H. Harris ◽  
Robert Chiew ◽  
Colin MacLeod

2010 ◽  
Vol 37 (2) ◽  
pp. 211-222 ◽  
Author(s):  
Michelle A. Josephson ◽  
Dianne B. McKay

Author(s):  
Harsha Adnani ◽  
Akshay Khatri ◽  
Nirav Agrawal ◽  
Ernesto Molmenti ◽  
Madhu Bhaskaran

AbstractDuring the ongoing pandemic, there have been varying presentations of coronavirus disease 2019 (COVID-19) infection, with the concern that patients who are immunosuppressed (due to underlying medical conditions and/or therapies) are at higher risk of severe disease. We report the case of an elderly renal transplant recipient working in a long-term health care facility who was being monitored by weekly surveillance testing and tested positive for COVID-19 by polymerase chain reaction (PCR) testing, despite having no clinical symptoms. He recovered with supportive care, despite being on multiple long-term immunosuppressant drugs and having multiple comorbidities. Additionally, it was found that he did not mount an antibody response, when he tested negative by serologic testing. Through this case, we wish to highlight the unique clinical scenario of asymptomatic patients who may have an underwhelming immune response to COVID-19, but may nevertheless be an important source of dissemination. We further discuss the probable mechanism of such asymptomatic presentations in immunosuppressed patients, while reinforcing the importance of self-isolation of COVID-19 patients (particularly in asymptomatic health care workers).


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