scholarly journals Relationship of White Matter Lesions with Intracerebral Hemorrhage Expansion and Functional Outcome: MISTIE II and CLEAR III

2020 ◽  
Vol 33 (2) ◽  
pp. 516-524 ◽  
Author(s):  
Björn M. Hansen ◽  
◽  
Natalie Ullman ◽  
John Muschelli ◽  
Bo Norrving ◽  
...  
Keyword(s):  
White Matter ◽  
Intracerebral Hemorrhage ◽  
Functional Outcome ◽  
White Matter Lesions ◽  
Relationship Of

White matter lesions and poor outcome after intracerebral hemorrhage: A nationwide cohort study

Neurology ◽  
2010 ◽  
Vol 74 (19) ◽  
pp. 1502-1510 ◽  
Author(s):  
S. H. Lee ◽  
B. J. Kim ◽  
W. S. Ryu ◽  
C. K. Kim ◽  
N. Kim ◽  
...  
Keyword(s):  
Cohort Study ◽  
White Matter ◽  
Intracerebral Hemorrhage ◽  
White Matter Lesions ◽  
Poor Outcome

Extents of White Matter Lesions and Increased Intraventricular Extension of Intracerebral Hemorrhage

2013 ◽  
Vol 41 (5) ◽  
pp. 1325-1331 ◽  
Author(s):  
Beom Joon Kim ◽  
Seung-Hoon Lee ◽  
Wi-Sun Ryu ◽  
Chi Kyung Kim ◽  
Jong-Won Chung ◽  
...  
Keyword(s):  
White Matter ◽  
Intracerebral Hemorrhage ◽  
White Matter Lesions

scholarly journals Differential Effect of White-Matter Lesions and Covert Brain Infarcts on the Risk of Ischemic Stroke and Intracerebral Hemorrhage

Stroke ◽  
2016 ◽  
Vol 47 (7) ◽  
pp. 1923-1925 ◽  
Author(s):  
Sara Kaffashian ◽  
Christophe Tzourio ◽  
Yi-Cheng Zhu ◽  
Bernard Mazoyer ◽  
Stéphanie Debette
Keyword(s):  
Ischemic Stroke ◽  
White Matter ◽  
Intracerebral Hemorrhage ◽  
Differential Effect ◽  
White Matter Lesions ◽  
Brain Infarcts

scholarly journals Relationship of white matter lesions and severity of pushing behavior after stroke

2017 ◽  
Vol 29 (12) ◽  
pp. 2116-2120
Author(s):  
Yuji Fujino ◽  
Kazu Amimoto ◽  
Satoshi Sugimoto ◽  
Kazuhiro Fukata ◽  
Masahide Inoue ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Lesions ◽  
Relationship Of

Association of white matter lesions and outcome after endovascular stroke treatment

Neurology ◽  
2020 ◽  
pp. 10.1212/WNL.0000000000010994
Author(s):  
Sven P.R. Luijten ◽  
Daniel Bos ◽  
Kars C.J. Compagne ◽  
Lennard Wolff ◽  
Charles B.L.M. Majoie ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
White Matter ◽  
Endovascular Treatment ◽  
Acute Ischemic Stroke ◽  
Functional Outcome ◽  
Treatment Effect ◽  
White Matter Lesions ◽  
Effect Modification ◽  
Stroke Treatment ◽  
Logistic Regression Models

ObjectiveTo investigate the association between white matter lesions (WML) and functional outcome in patients with acute ischemic stroke (AIS) and the modification of the effect of endovascular treatment (EVT) by WML.MethodsWe used data from the Multicenter Randomized Clinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands (MR CLEAN) trial and assessed severity of WML on baseline non-contrast CT imaging (NCCT; n = 473) according to the Van Swieten Scale. Post-stroke functional outcome was assessed with the modified Rankin Scale (mRS). We investigated the association of WML with functional outcome using ordinal logistic regression models adjusted for age, sex, and other relevant cardiovascular and prognostic risk factors. In addition, an interaction term between treatment allocation and WML severity was used to assess treatment effect modification by WML.ResultsWe found an independent negative association between more severe WML and functional outcome (acOR 0.77 [95% CI 0.66–0.90]). Patients with absent to moderate WML had similar benefit of EVT on functional outcome (acOR 1.93 [95% CI 1.31–2.84]) as patients with severe WML (acOR 1.95 [95% CI 0.90–4.20]). No treatment effect modification of WML was found (p for interaction = 0.85).ConclusionsWe found that more severe WML predict poor functional outcome after acute ischemic stroke, but do not modify effect of EVT.Classification of evidencePrognostic accuracy. This study provides Class II evidence that for patients with AIS, the presence of WML on baseline NCCT is associated with worse functional outcomes.

White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage

Neurology ◽  
2004 ◽  
Vol 63 (9) ◽  
pp. 1606-1612 ◽  
Author(s):  
E. E. Smith ◽  
M. E. Gurol ◽  
J. A. Eng ◽  
C. R. Engel ◽  
T. N. Nguyen ◽  
...  
Keyword(s):  
White Matter ◽  
Intracerebral Hemorrhage ◽  
White Matter Lesions ◽  
Recurrent Hemorrhage

White Matter Lesions Double the Risk of Post-Thrombolytic Intracerebral Hemorrhage

Stroke ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. 2149-2155 ◽  
Author(s):  
Sami Curtze ◽  
Elena Haapaniemi ◽  
Susanna Melkas ◽  
Satu Mustanoja ◽  
Jukka Putaala ◽  
...  
Keyword(s):  
White Matter ◽  
Intracerebral Hemorrhage ◽  
White Matter Lesions
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