scholarly journals A Promising Diagnostic Role of Immunohistochemical Expression of Insulin-Like Growth Factor II mRNA Binding Protein 3 (IMP3) in Pancreatic Lesions Using Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) Cytology

2022 ◽  
Author(s):  
Hayam E. Rashed ◽  
Awatef N. Nasr ◽  
Nora T. Wasfi ◽  
Ramy ElHendawy ◽  
Nelly M. Said
Keyword(s):  
Growth Factor ◽  
Needle Aspiration ◽  
Immunohistochemical Expression ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Factor Ii ◽  
Mrna Binding Protein ◽  
Diagnostic Role ◽  
Mrna Binding

scholarly journals A Promising Diagnostic Role of Immunohistochemical Expression of Insulin-Like Growth Factor II mRNA Binding Protein3 (IMP3) in Pancreatic Lesions Using Endoscopic Ultrasound –Guided –Fine Needle Aspiration (EUS-FNA) Cytology

2021 ◽  
Author(s):  
Hayam Rashed ◽  
Nora Wasfi ◽  
Awatef Nasr ◽  
Ramy ElHendawy ◽  
Nelly Mohammed Said
Keyword(s):  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
High Grade Dysplasia ◽  
High Grade ◽  
Immunohistochemical Expression ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Diagnostic Role

Abstract Background: Poor prognosis and short survival of patients harboring pancreatic cancer emerge how advanced disease it is. In a trial to achieve the earliest and most accurate diagnosis to manage this progressive disease, we proposed that using endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) with an adjuvant diagnostic immunohistochemical marker would give better diagnostic results. IMP3 has gained recently wide attention, as many studies found that IMP3 has not only diagnostic but also prognostic role in different types of malignancies. Aim of the study: this prospective work is to assess the diagnostic role of EUS-FNA combined with the immunohistochemical expression of IMP3 on different benign and malignant pancreatic lesions. Material and Method: the included pancreatic lesions (n=140) were obtained by EUS-FNA technique and stained for IMP3 immunohistochemically. Paraffin blocks from patients who underwent excision (n=92) or core biopsies (n=48) were performed for confirming diagnosis. Results: the combined method for diagnosis showed that IMP3 was positive in 78.7%, 91.7%, 100% PAC, Mucinous neoplasm with high grade dysplasia, IPMN with high grade dysplasia, respectively, while almost all benign lesions showed negative IMP3. Also, this method showed sensitivity (78.26%), specificity (95.83%), and accuracy (84.3%). Conclusion: EUS-FNA cytology with IMP3 could be a reliable diagnostic tool especially for assessment of malignant pancreatic lesions.

scholarly journals Role of Endoscopic Ultrasound-guided Fine-needle Aspiration in Lung and Mediastinal Lesions

2010 ◽  
Vol 73 (10) ◽  
pp. 523-529 ◽  
Author(s):  
Lien-Fu Lin ◽  
Pi-Teh Huang ◽  
Ming-Hung Tsai ◽  
Tsung-Ming Chen ◽  
Ka-Sic Ho
Keyword(s):  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle

scholarly journals Diagnosis of Abdominal Hydatid Cyst Disease: The Role of Ultrasound and Ultrasound-Guided Fine Needle Aspiration Cytology

2002 ◽  
Vol 11 (4) ◽  
pp. 190-195 ◽  
Author(s):  
Tareq Sinan ◽  
Mehraj Sheikh ◽  
Fayaz A. Chisti ◽  
Osama Al Saeed ◽  
Zafar Sheikh ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

scholarly journals Role of endoscopic ultrasound-guided fine needle aspiration and ultrasound-guided fine-needle aspiration in diagnosis of cystic pancreatic lesions

2015 ◽  
Vol 4 (2) ◽  
pp. 132 ◽  
Author(s):  
HusseinHassan Okasha ◽  
Mahmoud Ashry ◽  
HalaM. K. Imam ◽  
Reem Ezzat ◽  
Mohamed Naguib ◽  
...  
Keyword(s):  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Cystic Pancreatic Lesions
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