An immunophenotypic and molecular diagnosis of composite hairy cell leukaemia and chronic lymphocytic leukaemia

2013 ◽  
Vol 30 (4) ◽  
Author(s):  
Stuart Liptrot ◽  
David O’ Brien ◽  
Stephen E. Langabeer ◽  
Fiona Quinn ◽  
A. Jill Mackarel ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Molecular Diagnosis ◽  
Lymphocytic Leukaemia ◽  
Hairy Cell Leukaemia ◽  
Cell Leukaemia ◽  
Hairy Cell

Coexistent Hairy Cell Leukaemia and Chronic Lymphocytic Leukaemia

1998 ◽  
Vol 30 (1-2) ◽  
pp. 203-209 ◽  
Author(s):  
S. A. Brown ◽  
Julia Phillips ◽  
G. Ahsan ◽  
N. G. P. Slater
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Lymphocytic Leukaemia ◽  
Hairy Cell Leukaemia ◽  
Cell Leukaemia ◽  
Hairy Cell

scholarly journals A case of concomitant chronic lymphocytic leukaemia and hairy cell leukaemia evaluated forIGHV-D-Jrearrangements andBRAF-V600E mutation: lack of evidence for a common origin

2015 ◽  
Vol 174 (2) ◽  
pp. 329-331 ◽  
Author(s):  
Marzia Cavalli ◽  
Caterina Ilari ◽  
Ilaria Del Giudice ◽  
Marilisa Marinelli ◽  
Irene Della Starza ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Lymphocytic Leukaemia ◽  
Hairy Cell Leukaemia ◽  
Common Origin ◽  
Cell Leukaemia ◽  
Hairy Cell

Leukaemia

2018 ◽  
Author(s):  
Drew Provan ◽  
Trevor Baglin ◽  
Inderjeet Dokal ◽  
Johannes de Vos ◽  
Hassan Al-Sader
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Acute Lymphoblastic Leukaemia ◽  
Chronic Lymphocytic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Lymphocytic Leukaemia ◽  
Cell Leukaemia ◽  
Hairy Cell ◽  
Acute Myeloblastic Leukaemia ◽  
Prolymphocytic Leukaemia ◽  
Large Granular Lymphocyte Leukaemia

Acute myeloblastic leukaemia (AML) - Acute lymphoblastic leukaemia (ALL) - Chronic myeloid leukaemia (CML) - Chronic lymphocytic leukaemia (B-CLL) - Prolymphocytic leukaemia (PLL) - Hairy cell leukaemia and variant - Large granular lymphocyte leukaemia (LGLL) - Adult T-cell leukaemia-lymphoma (ATLL)

Detection of a Soluble form of the Receptor for Interleukin 2 in the Serum of Patients with Hairy Cell Leukaemia

1986 ◽  
Vol 1 (2) ◽  
pp. 101-104 ◽  
Author(s):  
Marco Chilosi ◽  
Giovanni Pizzolo ◽  
Gianpietro Semenzato ◽  
Gian Luigi Cetto
Keyword(s):  
Lymphocytic Leukaemia ◽  
Interleukin 2 ◽  
Normal Subjects ◽  
Hairy Cell Leukaemia ◽  
Soluble Form ◽  
Cell Leukaemia ◽  
Hairy Cell ◽  
Additional Tool ◽  
Activated T Lymphocytes ◽  
Chronic Lymphoproliferative Diseases

The sera of patients with hairy cell leukaemia (HCL) contain a factor which inhibits the binding of anti-IL-2R antibody to its target (activated T lymphocytes). The presence of this factor, which probably corresponds to the soluble form of IL-2R (sIL-2R), can be easily detected using a simple immunocytochemical inhibition assay. In a series of patients with chronic lymphoproliferative diseases the presence of sIL-2R appeared to be specific for HCL, using the sensitivity of our test, since it could not be detected in sera from normal subjects and patients with B-cell lymphocytic leukaemia or Hodgkin's disease. Thus it might be used as an additional tool for characterizing HCL patients.

Leukaemia

2015 ◽  
Author(s):  
Drew Provan ◽  
Trevor Baglin ◽  
Inderjeet Dokal ◽  
Johannes de Vos
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Acute Lymphoblastic Leukaemia ◽  
Chronic Lymphocytic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Lymphocytic Leukaemia ◽  
Cell Leukaemia ◽  
Hairy Cell ◽  
Acute Myeloblastic Leukaemia ◽  
Prolymphocytic Leukaemia ◽  
Large Granular Lymphocyte Leukaemia

Acute myeloblastic leukaemia (AML) - Acute lymphoblastic leukaemia (ALL) - Chronic myeloid leukaemia (CML) - Chronic lymphocytic leukaemia (B-CLL) - Prolymphocytic leukaemia (PLL) - Hairy cell leukaemia and variant - Large granular lymphocyte leukaemia (LGLL) - Adult T-cell leukaemia-lymphoma (ATLL)

Chronic leukaemias

2016 ◽  
pp. 754-781
Author(s):  
Hemant Malhotra ◽  
Lalit Kumar ◽  
Pankaj Malhotra ◽  
Devendra Hiwase ◽  
Ravi Bhatia
Keyword(s):  
Lymphocytic Leukaemia ◽  
Hairy Cell Leukaemia ◽  
Cell Leukaemia ◽  
Disease Monitoring ◽  
Hairy Cell ◽  
Future Directions ◽  
Hematopoietic System ◽  
Prolymphocytic Leukaemia ◽  
Chronic Leukaemia ◽  
Improvement In Survival

Chronic Leukaemia, as contrasted to the acute luekemia, are slowly growing clonal malignancies of the hematopoietic system in which, even without active intervention, survival is possible for several years. In the past decade there have been several advances in the basic understanding of these diseases which have lead to improvement in survival of several decades in the majority of patients which is now being referred to as ‘operational cure’. This chapter covers the chronic leukaemias (chronic myeloid leukaemia (CML), chronic lymphocytic leukaemia (CLL), hairy cell leukaemia, prolymphocytic leukaemia, large granular lymphocytic leukaemia (LGL), and hairy cell leukaemia variant (HCL-v), including epidemiology, staging and diagnosis, molecular biology, pathology, medical management, disease monitoring, management of relapse/refraction, and future directions.

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