Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study

2016 ◽  
Vol 33 (8) ◽  
Author(s):  
D. Pastuszak-Lewandoska ◽  
J. Kordiak ◽  
K. H. Czarnecka ◽  
M. Migdalska-Sęk ◽  
E. Nawrot ◽  
...  
2016 ◽  
Vol 11 (1) ◽  
pp. 264 ◽  
Author(s):  
Youchao Jia ◽  
Aimin Zang ◽  
Yanguang Feng ◽  
Xiao-Fang Li ◽  
Ke Zhang ◽  
...  

<p class="Abstract">It was aimed to explore the expression level of miRNA-486 and miRNA-499 in the plasma of lung cancer patients and analysis their differences in expre-ssion. The expression level of both miRNA-486 and miRNA-499 in the plasma of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) were lower than that of the control group (p&lt;0.05) and the decrease was more obvious in NSCLC. Compare with the miRNA-499,expression quantity in NSCLC patients plasma. There was statistical significance difference (p&lt;0.05) between III~Ⅳstage and I~II stage. The expression quantity of miRNA in plasma of patients with extensive-stage SCLC was lower than that of patients with limited-stage SCLC (p&lt;0.05). The sensitivity and specificity of plasms miRNA-486 respectively were 88.5% and 83.3%. The expression of miRNA-499 and miRNA-486 in lung cancer patients were up-regulated, and might be closely related to the occurrence and prognosis of lung cancer, and might be used as potential screening and prognosis index for lung cancer.</p><p> </p>


2019 ◽  
Vol 14 (10) ◽  
pp. S817-S818
Author(s):  
S. Lee ◽  
K. Pathak ◽  
M. Mcgilvrey ◽  
K. Mansfield ◽  
D. Cridebring ◽  
...  

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e15014-e15014
Author(s):  
Meera Yogarajah ◽  
Ebenezer Ofori Appah ◽  
Clive D. Morris ◽  
Katherine Baker Neblett ◽  
Greg Jones ◽  
...  

Lung Cancer ◽  
2011 ◽  
Vol 72 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Lee W. Jones ◽  
Neil D. Eves ◽  
Ivan Spasojevic ◽  
Frances Wang ◽  
Dora Il’yasova

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