Immunotherapy and predictive immunologic profile: the tip of the iceberg

2021 ◽  
Vol 38 (5) ◽  
Author(s):  
Tatiana Cunha Pereira ◽  
Paulo Rodrigues-Santos ◽  
Jani Sofia Almeida ◽  
Fábio Rêgo Salgueiro ◽  
Ana Raquel Monteiro ◽  
...  
Keyword(s):  
2015 ◽  
Vol 16 (10) ◽  
pp. 840-844 ◽  
Author(s):  
Zeeshan H Ahmad ◽  
Sukumaran Anil ◽  
Abdulsalam S Aljabab ◽  
Ibraheem HM Motabi ◽  
Abdullah Alrashed

ABSTRACT Lymphomas of the oral cavity are rare and typically present as intraosseous lesions that are most commonly diffuse large B-cell type. Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma histologically characterized by diffuse proliferation of large neoplastic B-lymphoid cells with a nuclear size equal to or exceeding normal histiocytic nuclei. A case of DLBCL of the mandible in an 18 years old male patient is presented. This report discusses this rare malignancy, including clinical presentation, histopathologic features, immunologic profile, treatment and prognosis. Though lymphoma of mandible is rare, it must be considered in differential diagnosis of swellings arising in the region. How to cite this article Alshahrani FAA, Aljabab AS, Motabi IHM, Alrashed A, Anil S. Primary Diffuse Large B-cell Lymphoma involving the Mandible. J Contemp Dent Pract 2015;16(10):840-844.


PEDIATRICS ◽  
1985 ◽  
Vol 76 (4) ◽  
pp. 508-511
Author(s):  
Michele Stegagno ◽  
Roberto Pascone ◽  
Patrizia Colarizi ◽  
Francesco Laurenti ◽  
Giancarlo Isacchi ◽  
...  

The immunologic status and the occurrence of alloimmunization against granulocytes, platelets, lymphocytes, and red cells was evaluated in 33 babies who received granulocyte transfusion because of neonatal sepsis. Nine age-matched babies were examined as control. A first group of 19 infants was examined only once between 6 and 23 months of age. Alloantibodies were searched by the following serologic methods: standard techniques for red cell antibodies; lymphocytotoxicity test; agglutination and immunofluorescence tests on granulocytes and platelets. No antibodies were demonstrated. The immunologic profile was investigated by determining the Ig levels, the percentage of E rosetteforming cells, and the lymphocyte blastic response to phytohemagglutinin and concanavalin A. Granulocyte function was studied by phagocytosis and killing of Candida. No significant differences were observed between treated and control babies. In a second group of 14 infants the occurrence of early immunization within 3 to 9 weeks after the last transfusion was investigated. No evidence of early immunization was found. The present data suggest that following neonatal granulocyte transfusion the risk of adverse immune reactions should be low.


2013 ◽  
Vol 89 (1) ◽  
pp. 40-47 ◽  
Author(s):  
Daniela M. Bernardi ◽  
Antonio F. Ribeiro ◽  
Tais N. Mazzola ◽  
Maria M.S. Vilela ◽  
Valdemiro C. Sgarbieri

2004 ◽  
Vol 191 (3) ◽  
pp. 815-820 ◽  
Author(s):  
Celine M. Radder ◽  
Dave L. Roelen ◽  
Ellen M.W. van de Meer-Prins ◽  
Frans H.J. Claas ◽  
Humphrey H.H. Kanhai ◽  
...  

1984 ◽  
Vol 55 (8) ◽  
pp. 461-467 ◽  
Author(s):  
Jon B. Suzuki ◽  
B. Christine Collison ◽  
William A. Falkler ◽  
Robert K. Nauman

2004 ◽  
Vol 9 (2) ◽  
pp. 106-107
Author(s):  
G Santuccio ◽  
L Sanvito ◽  
L Speciale ◽  
L Merlino ◽  
M Sgandurra ◽  
...  
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