Synthesis, characterization, X-ray crystal structure, electrochemical evaluation and anti-cancer studies of a mixed ligand Cu(II) complex of (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide

The electrochemical reduction and DNA binding have been studied for a series of platinum(IV) complexes with Cl-, OH-, and carboxylate anions as the axial ligands ; [Pt(en)Cl4], [Pt(en)Cl2(OH)2], and [Pt(en)Cl2(OC(O)R)2], R = CH3, CH2CH3, CH2CH2CH3. Cathodic reduction potentials vary by more than 650 mV with the tetrachloro complex reduced most readily and the dihydroxo least readily. The binding of the complexes correlates with the reduction potentials with the more readily reduced complexes binding more readily to DNA. The influence of the reducing agent glutathione on platinum binding to DNA was found to depend on whether it was added before or after Pt/DNA incubation. The results are consistent with octahedral platinum(IV) binding monofunctionally to DNA, and molecular modelling studies have been used to confirm that this is sterically feasible. The crystal structure of [Pt(en)Cl2(OC(O)CH3)2] has been determined by X-ray diffraction methods and refined to R = 0.028 (977 F). The crystals are monoclinic, space group C2/c, a 15.569(6), b 8.104(1), c 13.188(1) Ǻ, β 136.38(2)°.

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Mixed-ligand complexes of technetium Part XI. Nitridotechnetium complexes with tri- and tetradentate azomethines. X-ray molecular and crystal structure of [N-(2-ethoxycarbonyl-3-oxo-but-1-en(1)yl)-2-aminophenolato](triphenylphosphine)nitridotechnetium(V), TcN(ecbap)(Ph3P)

Inorganica Chimica Acta ◽

10.1016/s0020-1693(00)90160-9 ◽

1991 ◽

Vol 182 (2) ◽

pp. 233-238 ◽

Cited By ~ 11

Author(s):

Ulrich Abram ◽

Sonja Abram ◽

Rudolf Münze ◽

Ernst-Gottfried Jäger ◽

Joachim Stach ◽

...

Keyword(s):

Crystal Structure ◽

Mixed Ligand ◽

Molecular And Crystal Structure ◽

Mixed Ligand Complexes ◽

X Ray

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The first mixed-ligand coordination compound involving 8-aminoquinoline and pyridine-2,6-dicarboxylate: synthesis, X-ray crystal structure, and DFT studies

Journal of Coordination Chemistry ◽

10.1080/00958972.2015.1077953 ◽

2015 ◽

Vol 68 (20) ◽

pp. 3599-3610 ◽

Cited By ~ 7

Author(s):

Melika Eftekhar ◽

Masoud Mirzaei ◽

Azam Hassanpoor ◽

Iman Khosravi ◽

Antonio Bauzá ◽

...

Keyword(s):

Crystal Structure ◽

Coordination Compound ◽

Mixed Ligand ◽

Dft Studies ◽

X Ray ◽

Ligand Coordination

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Mixed-ligand complexes of technetium XII. Synthesis, characterization and X-ray crystal structure of (o-mercaptophenolato)bis[1,2-bis(dimethylphosphino)ethane] technetium(III) tetraphenylboranate, [Tc(meph)(DMPE)2](BPh4)

Inorganica Chimica Acta ◽

10.1016/s0020-1693(00)85413-4 ◽

1991 ◽

Vol 186 (2) ◽

pp. 151-154 ◽

Cited By ~ 8

Author(s):

Rudolf Münze ◽

Ulrich Abram ◽

Joachim Stach ◽

Wolfgang Hiller

Keyword(s):

Crystal Structure ◽

Mixed Ligand ◽

Mixed Ligand Complexes ◽

X Ray

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The Structure of the Tetranuclear Cubane-Like Nickel(II) Xanthate Alkoxide [Ni(C2H5OCS2)-(C5H4NCH2O)]4 as Its Acetone Solvate, an Example of a Non-Reversible Inclusion Compound

Australian Journal of Chemistry ◽

10.1071/ch9861035 ◽

1986 ◽

Vol 39 (7) ◽

pp. 1035 ◽

Cited By ~ 14

Author(s):

K Bizilj ◽

SG Hardin ◽

BF Hoskins ◽

PJ Oliver ◽

ERT Tiekink ◽

...

Keyword(s):

Crystal Structure ◽

Inclusion Compound ◽

Mixed Ligand ◽

X Ray Diffraction ◽

Triclinic Space Group ◽

Space Group ◽

X Ray ◽

Oxygen Atoms

The crystal structure of the acetone solvate of a mixed ligand tetranuclear nickel(II) complex involving the pyridine-2-methoxide ( pym ) and 0-ethylxanthate (exa) anions has been determined by X-ray diffraction methods. Crystals of [Ni (exa)( pym )]4.Me2CO are triclinic, space group Pī , a 13.825(2), b 15.606(3), c 12.288(2)Ǻ, α 101.16(2), β 101.38(1), γ 85.80(1)°, with Z 2; R and Rw were 0.056 and 0.057 respectively for 4,771 unique reflections for which I ≥ 3σ(I). The structure consists of tetranuclear cubane -like clusters with four nickel and four oxygen atoms arranged at alternate corners of a distorted cube. The discrete molecules of occluded acetone are located in cavities defined by the [Ni( exa )( pym )]4 units.

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