Analysis of related factors of cervical intraepithelial neoplasia complicated with vaginal intraepithelial neoplasia

2022 ◽  
Author(s):  
Y.Y. Zhang ◽  
R. Xia ◽  
D. Chen ◽  
X. Zhang
Keyword(s):  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
Related Factors ◽  
Vaginal Intraepithelial Neoplasia

scholarly journals Molecular Cloning and Nucleotide Sequence Analysis of a Novel Human Papillomavirus (Type 82) Associated with Vaginal Intraepithelial Neoplasia

2000 ◽  
Vol 7 (1) ◽  
pp. 91-95 ◽  
Author(s):  
Nao Kino ◽  
Tetsutaro Sata ◽  
Yuko Sato ◽  
Motoyasu Sugase ◽  
Toshihiko Matsukura
Keyword(s):  
Human Papillomavirus ◽  
Nucleotide Sequence ◽  
Cervical Intraepithelial Neoplasia ◽  
Sequence Similarity ◽  
Blot Hybridization ◽  
Intraepithelial Neoplasia ◽  
Etiologic Agent ◽  
Nucleotide Sequence Analysis ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Vaginal Intraepithelial Neoplasia

ABSTRACT The genome of a novel human papillomavirus (HPV-82) was cloned from a vaginal intraepithelial neoplasia grade I. In our series of 291 biopsy specimens, HPV-82 was identified in one case each of cervical intraepithelial neoplasia grade II and grade III by blot hybridization. The histological localization of HPV-82 DNA in the three lesions was confirmed by in situ hybridization. The results indicated that HPV-82 is an etiologic agent for vaginal and cervical intraepithelial neoplasia. By nucleotide sequence similarity of L1 open reading frame (ORF), HPV-82 was closely related to HPV-26, -51, and -69. To know the precise relationship between the HPVs, we determined the complete sequence of HPV-82, as well as that of HPV-69. Sequencing revealed that the four HPVs had no initiation codon in the E5 ORF and had extensive nucleotide sequence similarities in all ORFs. In addition, they exhibited unique frame position patterns for ORFs, different from those of the other genital HPVs.

scholarly journals Clinical analysis of cervical intraepithelial neoplasia with vaginal intraepithelial neoplasia

Medicine ◽  
2017 ◽  
Vol 96 (17) ◽  
pp. e6700
Author(s):  
Yue He ◽  
Qun Zhao ◽  
Yu-Ning Geng ◽  
Shu-Li Yang ◽  
Cheng-Hong Yin ◽  
...  
Keyword(s):  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
Clinical Analysis ◽  
Vaginal Intraepithelial Neoplasia
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