Sinonasal SMARCB1 (INI1) Deficient Carcinoma with Yolk Sac Tumor Differentiation: A Case Report and Treatment Options

2021 ◽  
Author(s):  
Burak Hazir ◽  
Berkay Şímșek ◽  
Arzu Erdemír ◽  
Fatih Gürler ◽  
Ozan Yazici ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Options ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Tumor Differentiation

scholarly journals Case Report: SMARCB1 (INI-1)-Deficient Carcinoma of the Nasal Cavity with Pure Yolk Sac Tumor Differentiation and Elevated Serum AFP Levels

2021 ◽  
Vol Volume 14 ◽  
pp. 2227-2233
Author(s):  
Chun-Yu Li ◽  
Ya-mei Han ◽  
Ke Xu ◽  
Shu-yue Wu ◽  
Xu-Yong Lin ◽  
...  
Keyword(s):  
Case Report ◽  
Nasal Cavity ◽  
Elevated Serum ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Tumor Differentiation

scholarly journals Yolk sac tumor in the abdominal wall of an 18-month-old girl: a case report

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
Machiel van den Akker ◽  
Dirk Vervloessem ◽  
An Huybrechs ◽  
Sabine Declercq ◽  
Jutte van der Werff ten Bosch
Keyword(s):  
Case Report ◽  
Abdominal Wall ◽  
Yolk Sac ◽  
Yolk Sac Tumor

scholarly journals Yolk sac tumor of the endometrium in a post-menopausal woman: Case report and review of the literature

2021 ◽  
pp. 100748
Author(s):  
Risha Sinha ◽  
Bethany Bustamante ◽  
Alexander Truskinovsky ◽  
Gary L. Goldberg ◽  
Karin K. Shih
Keyword(s):  
Case Report ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Menopausal Woman ◽  
Review Of The Literature ◽  
Post Menopausal Woman ◽  
Post Menopausal

scholarly journals 270 A Case Report on a Primary Hepatic Yolk Sac Tumor in a Middle-Aged Woman—A Challenging Diagnosis

2018 ◽  
Vol 149 (suppl_1) ◽  
pp. S115-S115
Author(s):  
Andrey Prilutskiy ◽  
Josenia Tan ◽  
Qing Zhao
Keyword(s):  
Case Report ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Middle Aged ◽  
Aged Woman ◽  
Middle Aged Woman

scholarly journals Ovarian Yolk Sac Tumor: A Case Report with Review Of Literature

2016 ◽  
Vol 2 (1) ◽  
pp. 15-17
Author(s):  
A Sreehari ◽  
BM Rupakala
Keyword(s):  
Case Report ◽  
Early Adulthood ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Histological Subtype ◽  
Review Of Literature ◽  
Yolk Sac Tumors ◽  
Ovarian Dysgerminoma

ABSTRACT A total of 3 to 5% of all ovarian malignancies include malignant ovarian germ cell tumors (MOGCTs). They are subdivided into germinomatous and non-germinomatous tumors. Common types of non-germinomatous tumors include yolk sac and immature teratoma. Ovarian yolk sac tumors (YST) are the second most frequent histological subtype of MOGCTs, after ovarian dysgerminoma. They account for 20% of MOGCTs and are frequent especially in childhood and in early adulthood. We report the case of a yolk sac tumor of the ovary in a 13yrs years old female. How to cite this article Sreehari A, Rupakala BM, Sarojamma C. Ovarian Yolk Sac Tumor: A Case Report with Review of Literature. J Med Sci 2016;2(1):15-17.

scholarly journals Somatically derived Yolk Sac tumor of the urinary bladder: A case report and differential diagnosis

2020 ◽  
Author(s):  
Nadia Espejo-Herrera ◽  
Enric Condom Mundó
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Final Diagnosis ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
High Grade ◽  
Yolk Sac Tumors ◽  
Urinary Bladder Tumor

Abstract Background: Yolk sac tumor is a germ cell neoplasm that arises predominantly in the gonads, but can also derive from somatic neoplasms in extragonadal locations. These cases have been denominated recently as “somatically derived Yolk sac tumors”, and have been documented in several locations, although reports from the urinary tract are scarce. To our knowledge, this is the first report of a Yolk sac tumor derived from urothelial carcinoma. Case presentation: We present a unique case of a 76-year-old man with a recurrent urinary bladder tumor, initially interpreted as a high grade urothelial carcinoma with glandular differentiation. In the recurrent tumor, diverse histological patterns were identified, including glandular, hepatoid and sarcomatoid. This tumor showed positivity for AFP, GLP3 and SALL4, and negativity for CK7 and EMA. Fluorescent in situ hybridization study showed a polysomic pattern of chromosome 12. All these findings led to the final diagnosis of a Yolk sac tumor derived from urothelial carcinoma. Conclusions: Somatically derived Yolk Sac tumors should be considered in the differential diagnosis of a high grade urothelial carcinoma, particularly when glandular and other unusual patterns are observed. Key words: Yolk sac tumor, somatically derived, urothelial carcinoma, urinary bladder, case report.

scholarly journals Urachal yolk sac tumor penetrating the bladder as a diagnostic challenge: a case report and review of the literature

2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Vladimír Šámal ◽  
Tomáš Jirásek ◽  
Vít Paldus ◽  
Igor Richter ◽  
Ondřej Hes
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Review Of The Literature ◽  
Diagnostic Challenge ◽  
Macroscopic Hematuria ◽  
Rare Case Report

Abstract Background Yolk sac tumor (YST) is a germ cell tumor. It is primarily located in the gonads but can also occur extragonadally (extragonadal yolk sac tumor - EGYST), most commonly in the pelvis, retroperitoneum or mediastinum. Only a few YSTs of the urachus have been described. Case report We present a rare case report of a 37-year-old male with episodes of macroscopic hematuria. The histological specimen obtained by transurethral resection showed a solid, and in some parts papillary infiltrative, high-grade tumor with numerous areas of marked nuclear atypia and clear invasion between the detrusor bundles. Glandular pattern has been observed in only minority of the tumor. Immunohistochemistry showed significant positivity for GPC3, SALL4 and cytokeratins AE1/AE3, while KRT7 and GATA3 were negative. We concluded that the biopsy findings were consistent with urothelial carcinoma with infrequent YST differentiation. In definitive surgical specimens we found a malignant epithelial, glandular and cystically arranged tumor of germinal appearance arising from urachus. The surrounding urothelium was free of invasive or in situ tumor changes. We reclassified the tumor as a urachal YST. Conclusion EGYST was suspected because glandular and hepatoid structures were found, but the presence of these structures should be verified by immunohistochemistry.

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