Clinical outcomes of gemtuzumab ozogamicin for relapsed acute myeloid leukemia: single-institution experience

Author(s):  
Naoko Hosono ◽  
Miyuki Ookura ◽  
Hiroaki Araie ◽  
Mihoko Morita ◽  
Kazuhiro Itoh ◽  
...  
2021 ◽  
Vol 9 ◽  
pp. 2050313X2110155
Author(s):  
Sachio Fujita ◽  
Ryosuke Matsuno ◽  
Naoko Kawabata ◽  
Yumiko Sugishita ◽  
Ryota Kaneko ◽  
...  

Limited salvage chemotherapies are available for relapsed/refractory acute myeloid leukemia. Herein, we described successful reinduction chemotherapy, involving a combination of clofarabine, cyclophosphamide, and etoposide, in a 12-year-old male with relapsed acute myeloid leukemia prior to allogeneic bone marrow transplantation from his father. Although treatment with a combination of fludarabine, cytarabine, granulocyte colony-stimulating factor, idarubicin, and gemtuzumab ozogamicin had no positive effects, the aforementioned clofarabine-based chemotherapy induced complete remission and allowed the transplantation to go ahead. The abovementioned regimen may be useful for induction chemotherapy prior to hematopoietic stem cell transplantation for refractory/relapsed acute myeloid leukemia.


2003 ◽  
Vol 27 (10) ◽  
pp. 893-897 ◽  
Author(s):  
Apostolia Tsimberidou ◽  
Jorge Cortes ◽  
Deborah Thomas ◽  
Guillermo Garcia-Manero ◽  
Srdan Verstovsek ◽  
...  

2018 ◽  
Vol 18 (5) ◽  
pp. 346-352.e5 ◽  
Author(s):  
Bruno C. Medeiros ◽  
Tiffany N. Tanaka ◽  
Larisa Balaian ◽  
Asad Bashey ◽  
Amy Guzdar ◽  
...  

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