Results of Locoregional Radiotherapy or Axillary Dissection in Early Breast Cancer with pN0(is +) and pN1mi Nodal Disease

2022 ◽  
Author(s):  
Ayse Altinok ◽  
Fatma Tokat ◽  
Umit Ince ◽  
Cihan Uras ◽  
Nuran Bese
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Axillary Dissection ◽  
Nodal Disease

532 Is Axillary Dissection Still Useful in Node-negative Early Breast Cancer?

2012 ◽  
Vol 48 ◽  
pp. S201
Author(s):  
F. Petrelli ◽  
M. Cabiddu ◽  
M. Ghilardi ◽  
K. Borgonovo ◽  
S. Barni
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Axillary Dissection ◽  
Node Negative

scholarly journals Surgeon Attitudes Toward the Omission of Axillary Dissection in Early Breast Cancer

JAMA Oncology ◽  
2018 ◽  
Vol 4 (11) ◽  
pp. 1511 ◽  
Author(s):  
Monica Morrow ◽  
Reshma Jagsi ◽  
M. Chandler McLeod ◽  
Dean Shumway ◽  
Steven J. Katz
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Axillary Dissection

Sentinel node biopsy or limited oriented axillary dissection (LOAD) in early breast cancer

2005 ◽  
Vol 31 (9) ◽  
pp. 949-953 ◽  
Author(s):  
R.J. Salmon ◽  
A. Marcolet ◽  
M. Vieira ◽  
O. Languille
Keyword(s):  
Breast Cancer ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Early Breast Cancer ◽  
Axillary Dissection ◽  
Node Biopsy

SP8.1.7 Sentinel Lymph Node Biopsy or Neoadjuvant Chemotherapy- What comes first?

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Smriti Karki ◽  
Yasmin Hassen ◽  
Arunmoy Chakravorty ◽  
Karolina Ajauskaite ◽  
Ekambaram Dinkara Babu
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Neoadjuvant Chemotherapy ◽  
Early Breast Cancer ◽  
Lymph Node Biopsy ◽  
Axillary Lymph ◽  
Nodal Disease ◽  
Node Biopsy

Abstract Aims NICE guidelines have not defined the timing of Sentinel Lymph Node Biopsy (SLNB) with respect to neoadjuvant chemotherapy (NACT). While there is an ongoing debate, the emerging consensus is in favour of SLNB following NACT in clinically node-negative (cN0) patients which confers the advantage of better prognostic outcomes as a negative SLNB negates further Axillary Lymph Node Dissection (ALND) and prevents patients having further unnecessary surgery. Thus, the aim of the study was to establish whether unnecessary ALND can be safely avoided by performing SLNB after NACT. Method Retrospective case records review of all patients treated with ALND at a single institution was undertaken from January 2018 to December 2019. Results 73 patients had ALND in this time frame. Patients received SLNB before NACT and ALND was performed if they were found node-positive on SLNB. Out of 73 patients, 24 patients had no further nodal disease, 26 had 1-2 macrometastasis and 23 had 3 or more macrometastasis on ALND. 57/73 patients had early breast cancer (T1/T2). 21/57 were cN0 but and 5/21 had NACT following SLNB and ALND after NACT. Of the 5 patients, 2 (40%) had no nodal disease on ALND. Conclusion 40% patients could have avoided ALND if SLNB was done after NACT. Also, 68% (50/73) patients who had ALND only had <2 lymph node macrometastasis. This data implies that patients with early breast cancer may be getting subjected to a second operation which not only is unnecessary but also may have debilitating complications.

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