scholarly journals Membrane-mediated amyloid deposition of human islet amyloid polypeptide

2017 ◽  
Vol 10 (2) ◽  
pp. 453-462 ◽  
Author(s):  
Kenji Sasahara
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Amyloid Deposition ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice

Metabolism ◽  
1999 ◽  
Vol 48 (4) ◽  
pp. 448-454 ◽  
Author(s):  
Gunilla Westermark ◽  
Per Westermark ◽  
Decio L. Eizirik ◽  
Claes Hellerström ◽  
Niles Fox ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Nude Mice ◽  
Islet Amyloid Polypeptide ◽  
Human Islets ◽  
Amyloid Deposition ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2126-P
Author(s):  
ANDREW T. TEMPLIN ◽  
MAHNAZ MELLATI ◽  
DANIEL ZEMAN-MEIER ◽  
MEGHAN F. HOGAN ◽  
NATHALIE ESSER ◽  
...  
Keyword(s):  
Beta Cell ◽  
Islet Amyloid Polypeptide ◽  
Amyloid Deposition ◽  
Human Islet ◽  
Cell Secretion ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide ◽  
Beta Cell Secretion

scholarly journals The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice

Diabetologia ◽  
2003 ◽  
Vol 46 (1) ◽  
pp. 71-79 ◽  
Author(s):  
J. Vidal ◽  
C. Bruce Verchere ◽  
S. Andrikopoulos ◽  
F. Wang ◽  
R. Hull ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Apolipoprotein E ◽  
Islet Amyloid Polypeptide ◽  
Amyloid Deposition ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans

Diabetes ◽  
1994 ◽  
Vol 43 (5) ◽  
pp. 640-644 ◽  
Author(s):  
E. J. de Koning ◽  
J. W. Hoppener ◽  
J. S. Verbeek ◽  
C. Oosterwijk ◽  
K. L. van Hulst ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

Biochimie ◽  
2020 ◽  
Vol 170 ◽  
pp. 26-35 ◽  
Author(s):  
Shadai Salazar Vazquez ◽  
Bertrand Blondeau ◽  
Pierre Cattan ◽  
Mathieu Armanet ◽  
Ghislaine Guillemain ◽  
...  
Keyword(s):  
Cell Death ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12815-12825
Author(s):  
Yajie Wang ◽  
Feihong Meng ◽  
Tong Lu ◽  
Chunyun Wang ◽  
Fei Li
Keyword(s):  
Metal Ions ◽  
Metal Binding ◽  
Membrane Damage ◽  
Islet Amyloid Polypeptide ◽  
Divalent Metal ◽  
Human Islet ◽  
Divalent Metal Ions ◽  
Islet Amyloid ◽  
Induced Membrane ◽  
Human Islet Amyloid Polypeptide

Their is a counteraction between a decrease in the disruptive ability of metal-associated oligomer species and an increase in the quantity of oligomers promoted by the metal binding in the activity of hIAPP induced membrane damage.

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