Sweet Strategies in Prostate Cancer Biomarker Research: Focus on a Prostate Specific Antigen

2017 ◽  
Vol 8 (2) ◽  
pp. 690-700 ◽  
Author(s):  
Pavel Damborský ◽  
Dominika Damborská ◽  
Štefan Belický ◽  
Ján Tkáč ◽  
Jaroslav Katrlík
2008 ◽  
Vol 100 (21) ◽  
pp. 1487-1488 ◽  
Author(s):  
Ian M. Thompson ◽  
Catherine M. Tangen ◽  
Alan R. Kristal

2014 ◽  
Vol 395 (9) ◽  
pp. 915-929 ◽  
Author(s):  
Morley D. Hollenberg

Abstract Human kallikrein-related peptidases (KLKs), including the well-known prostate cancer biomarker, prostate-specific antigen (PSA-KLK3), along with 14 other serine proteinase KLK family members are now known to regulate cells by cleaving and activating members of the G-protein-coupled proteinase-activated receptor (PAR) family. This hormone-like signaling action of the KLKs has provided a new perspective for understanding the biological roles that KLKs may play in normal and pathophysiological settings. This overview summarizes the circumstances leading up to the discovery of this action of the KLKs and provides an overview of the diverse impact on tissue function that may result from KLK-triggered PAR activation.


2004 ◽  
Vol 171 (4S) ◽  
pp. 334-334
Author(s):  
Walter J. Simoneaux ◽  
Caleb B. Bozeman ◽  
Brett S. Carver ◽  
Donald A. Elmajian

2004 ◽  
Vol 171 (4S) ◽  
pp. 439-440
Author(s):  
Yoshio Naya ◽  
Herbert A. Fritsche ◽  
Viju A. Bhadkamkar ◽  
Stephen D. Mikolajczyk ◽  
Harry G. Rittenhouse ◽  
...  

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