Synthesis, Biocompatibility, and Relaxometric Properties of Heavily Loaded Apoferritin with D-Glucuronic Acid-Coated Ultrasmall Gd2O3 Nanoparticles

2021 ◽  
Author(s):  
Xu Miao ◽  
Huan Yue ◽  
Son Long Ho ◽  
Hyunsil Cha ◽  
Shanti Marasini ◽  
...  
Keyword(s):  
Glucuronic Acid ◽  
Gd2o3 Nanoparticles

CHROMATOGRAPHIC STUDIES ON 131I-COMPOUNDS IN FAECES AND BILE

1964 ◽  
Vol 47 (2) ◽  
pp. 343-352
Author(s):  
B. Blomstedt ◽  
H. Y. Neujahr
Keyword(s):  
Intravenous Administration ◽  
Glucuronic Acid ◽  
Free Triiodothyronine ◽  
Considerable Part ◽  
Human Faeces ◽  
Total Excretion

ABSTRACT The occurrence of 131I-compounds in human faeces was studied after intravenous administration of 131I-thyroxine. The excretion of the radioactivity during 12 days ranged from 7.8 to 32.1 per cent of the dose administered with a mean of 16.0 (± 1.76). The radioactivity in the faeces was derived from free 131I-thyroxine. The total amount of faeces did not seem to influence the total excretion of the dose administered. After administration of 131I-triiodothyronine to rats and humans, triiodothyronine occurred in the bile mainly conjugated with glucuronic acid, but a considerable part of the radioactivity was found in diiodotyrosine. The radioacivity of human faeces after the administration of 131I-triiodothyronine was derived from free triiodothyronine. After injection of 131I-diiodotyrosine only labelled iodide was detected in the bile of rats. In the bile of humans most of the radioactivity was derived from iodide, and a small part of it was found in diiodotyrosine.

Binding of lead and copper(II) cations to hemicelluloses of rye bran

1986 ◽  
Vol 51 (10) ◽  
pp. 2250-2258 ◽  
Author(s):  
Rudolf Kohn ◽  
Zdena Hromádková ◽  
Anna Ebringerová
Keyword(s):  
Uronic Acid ◽  
Equilibrium Solution ◽  
Glucuronic Acid ◽  
The Other ◽  
Carboxyl Groups ◽  
Stoichiometric Ratio ◽  
Molar Ratios ◽  
Free Ions ◽  
Uronic Acid Content ◽  
The Relationship

Several fractions of acid hemicelluloses isolated from rye bran were characterized by molar ratios of saccharides (D-Xyl, L-Ara, D-Glc, D-Gal) and 4-O-methyl-D-glucuronic acid and protein content. Binding of Pb2+ and Cu2+ ions to these acid polysaccharides was considered according to function (M)b = f([M2+]f), expressing the relationship between the amount of metal (M)b bound to 1 g of the substance and the concentration of free ions [M2+]f in the equilibrium solution and according to the association degree β of these cations with carboxyl groups of uronic acid at a stoichiometric ratio of both components in the system under investigation. Acid hemicelluloses contained only a very small portion of uronic acid ((COOH) 0.05-0.18 mmol g-1); the model polysaccharide, 4-O-methyl-D-glucurono-D-xylan of beech, was substantially richer in uronic acid content ((COOH) 0.73 mmol g-1). Consequently, the amount of lead and copper bound to acid hemicelluloses is very small ((M)b 0.017-0.025 mmol g-1) at [M2+]f = 0.10 mmol l-1. On the other hand, much greater amount of cations ((M)f 0.09-0.10 mmol g-1) was bound to the glucuronoxylan. The association degree β was like with the majority of samples (β = 0.31-0.38). The amount of lead and copper(II) bound to acid hemicelluloses from rye bran is several times lower than that bound to dietary fiber isolated from vegetables (cabbage, carrot), rich in pectic substances.

scholarly journals Detection of Acetaminophen and Its Glucuronide in Fingerprint by SALDI Mass Spectrometry Using Zeolite and Study of Time-Dependent Changes in Detected Ion Amount

Analytica ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 66-75
Author(s):  
Toshiki Horikoshi ◽  
Chihiro Kitaoka ◽  
Yosuke Fujii ◽  
Takashi Asano ◽  
Jiawei Xu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Glucuronic Acid ◽  
Laser Desorption ◽  
The Body ◽  
Time Dependent ◽  
Laser Desorption Ionization ◽  
Fingerprint Analysis ◽  
Desorption Ionization ◽  
Acid Conjugate ◽  
Over Time

The ingredients of an antipyretic (acetaminophen, AAP) and their metabolites excreted into fingerprint were detected by surface-assisted laser desorption ionization (SALDI) mass spectrometry using zeolite. In the fingerprint taken 4 h after AAP ingestion, not only AAP but also the glucuronic acid conjugate of AAP (GAAP), caffeine (Caf), ethenzamide (Eth), salicylamide (Sala; a metabolite of Eth), and urea were detected. Fingerprints were collected over time to determine how the amounts of AAP and its metabolite changed with time, and the time dependence of the peak intensities of protonated AAP and GAAP was measured. It was found that the increase of [GAAP+H]+ peak started later than that of [AAP+H]+ peak, reflecting the metabolism of AAP. Both AAP and GAAP reached maximum concentrations approximately 3 h after ingestion, and were excreted from the body with a half-life of approximately 3.3 h. In addition, fingerprint preservation was confirmed by optical microscopy, and fingerprint shape was retained even after laser irradiation of the fingerprint. Our method may be used in fingerprint analysis.

scholarly journals DERIVATIVES OF GLUCURONIC ACID

1933 ◽  
Vol 100 (3) ◽  
pp. 743-748 ◽  
Author(s):  
Walther F. Goebel ◽  
Frank H. Babers
Keyword(s):  
Glucuronic Acid ◽  
Derivatives Of

Design strategy of ultrasmall Gd2O3 nanoparticles for T1 MRI with high performance

2021 ◽  
Author(s):  
Jianfeng Yang ◽  
Pengyuan Shan ◽  
Qingling Zhao ◽  
Shuquan Zhang ◽  
Lanlan Li ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Performance ◽  
Design Strategy ◽  
Resonance Imaging ◽  
Relative Time ◽  
Time Parameters ◽  
Gd2o3 Nanoparticles

It is still a big challenge for designing Gd3+ based nanoparticles (NPs) for T1 MRI (Magnetic Resonance Imaging) with high performance and clarifying the effects of relative time parameters for...

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