Cytochrome P450 1A1 (CYP1A1) polymorphism and susceptibility to esophageal cancer: an updated meta-analysis of 27 studies

Tumor Biology ◽  
2014 ◽  
Vol 35 (10) ◽  
pp. 10351-10361 ◽  
Author(s):  
Feng-Feng Gong ◽  
Shan-Shan Lu ◽  
Cai-Yun Hu ◽  
Zhen-Zhong Qian ◽  
Fang Feng ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cytochrome P450 ◽  
Meta Analysis ◽  
Cytochrome P450 1A1 ◽  
Cyp1a1 Polymorphism

Association between cytochrome P450 1A1 MspI polymorphism and endometrial cancer risk: a meta-analysis

Tumor Biology ◽  
2013 ◽  
Vol 34 (5) ◽  
pp. 2545-2550 ◽  
Author(s):  
Linxiao Han ◽  
Yanyan Liu ◽  
Weiwei Cao ◽  
Xiuying Yuan ◽  
Cuifeng Li
Keyword(s):  
Cytochrome P450 ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Cytochrome P450 1A1 ◽  
Endometrial Cancer Risk ◽  
Mspi Polymorphism

scholarly journals Cytochrome P450 1A1 (CYP1A1) T3801C and A2455G polymorphisms in breast cancer risk: a meta-analysis

2007 ◽  
Vol 52 (5) ◽  
pp. 423-435 ◽  
Author(s):  
Chengwen Chen ◽  
Yan Huang ◽  
Yao Li ◽  
Yumin Mao ◽  
Yi Xie
Keyword(s):  
Breast Cancer ◽  
Cytochrome P450 ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Cytochrome P450 1A1

Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ovarian cancer risk: a meta-analysis

2012 ◽  
Vol 39 (11) ◽  
pp. 9921-9930 ◽  
Author(s):  
Theodoros N. Sergentanis ◽  
Konstantinos P. Economopoulos ◽  
Souzana Choussein ◽  
Nikos F. Vlahos
Keyword(s):  
Ovarian Cancer ◽  
Cytochrome P450 ◽  
Cancer Risk ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Ovarian Cancer Risk ◽  
Cytochrome P450 1A1 ◽  
Cyp1a1 Gene

Cytochrome P450 1A1 Gene Polymorphisms and Endometrial Cancer Risk: A Meta-Analysis

2011 ◽  
Vol 21 (2) ◽  
pp. 323-331 ◽  
Author(s):  
Theodoros N. Sergentanis ◽  
Konstantinos P. Economopoulos ◽  
Souzana Choussein ◽  
Nikos F. Vlahos
Keyword(s):  
Cytochrome P450 ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Random Effects ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Cytochrome P450 1A1 ◽  
Case Control Studies ◽  
Endometrial Cancer Risk ◽  
Random Effects Models

Introduction:This meta-analysis aims to examine whether the genotype status of Msp1, Ile462Val, and Thr461Asn polymorphisms in cytochrome P450 1A1 (CYP1A1) is associated with endometrial cancer risk.Methods:Eligible case-control studies were identified through search in MEDLINE (end of search: August 2010). Pooled odds ratios (ORs) were appropriately derived from fixed-effects or random-effects models.Results:ConcerningMspI polymorphism, 8 studies were eligible (1456 cases and 2371 controls); 9 studies were eligible (1889 cases and 3662 controls) for Ile462Val and 6 studies were eligible (1272 cases and 2122 controls) for Thr461Asn.MspI polymorphism was not associated with endometrial cancer risk (for heterozygous TC vs TT carriers: OR = 0.83, 95% confidence interval [CI], 0.59-1.15, random effects; for homozygous CC vs TT carriers: OR = 1.00, 95% CI, 0.55-1.82, fixed effects). Similarly, Ile462Val polymorphism was not associated with endometrial cancer risk (for heterozygous Ile/Val vs Ile/Ile carriers: OR = 1.27, 95% CI, 0.78-2.06, random effects; for homozygous Val/Val vs Ile/Ile carriers: OR = 1.16, 95% CI, 0.48-2.81, fixed effects). Accordingly, Thr461Asn status was not significantly associated with endometrial cancer risk. The same results were reproduced in Caucasians.Conclusions:The 3 examined CYP1A1 genotype polymorphisms do not seem to confer any additional risk for endometrial cancer in Caucasians. Accumulation of further data seems mandatory for future race-specific analyses.

scholarly journals Cytochrome P450 1A1 gene polymorphisms and digestive tract cancer susceptibility: a meta-analysis

2016 ◽  
Vol 20 (9) ◽  
pp. 1620-1631 ◽  
Author(s):  
Anjing Ren ◽  
Tingting Qin ◽  
Qianqian Wang ◽  
Haina Du ◽  
Donghua Zhong ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Digestive Tract ◽  
Gene Polymorphisms ◽  
Cancer Susceptibility ◽  
Meta Analysis ◽  
Cytochrome P450 1A1 ◽  
Digestive Tract Cancer ◽  
Tract Cancer
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