scholarly journals What Is the Best for Colon Preparation: Single-Dose, Split-Dose or Add-ons to Polyethylene Glycol?

2021 ◽  
Vol 58 (12) ◽  
pp. 1115-1116
Author(s):  
Ujjal Poddar ◽  
Srinivas Srinidhi Vadlapudi
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Split Dose ◽  
Colon Preparation

Split dose versus full single-dose regimen of polyethylene glycol for bowel preparation in pediatric colonoscopy

2019 ◽  
pp. 1
Author(s):  
Hansa Sriphongphankul ◽  
Pornthep Tanpowpong ◽  
Chatmanee Lertudomphonwanit ◽  
Suporn Treepongkaruna
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Dose Regimen ◽  
Split Dose ◽  
Pediatric Colonoscopy

scholarly journals Gastric Residual Volume after Split-Dose Bowel Preparation versus Conventional Single-Dose Regimen before Anesthetic Colonoscopy

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Shi-gui Xue ◽  
Han-lin Chen ◽  
Chun-sheng Cheng ◽  
Bao-sheng Huang ◽  
Hou-de Zhang
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Dose Group ◽  
Prospective Observational Study ◽  
Residual Volume ◽  
Gastric Residual Volume ◽  
Split Dose ◽  
Bowel Cleansing ◽  
Risk Of Aspiration

The aim of this study was to compare gastric residual volume (GRV) in patients given a split-dose versus a conventional single-dose of polyethylene glycol (PEG) preparation before undergoing anesthetic colonoscopy. Methods. In a prospective observational study, we assessed GRV in outpatients undergoing same-day anesthetic gastroscopy and colonoscopy between October 8 and December 30 of 2016. Outpatients were assigned to the split-dose (1 L PEG in the prior evening and 1 L PEG 2–4 h before endoscopy) or single-dose (ingestion of 2 L PEG ≥ 6 h before endoscopy) regimen randomly. Bowel cleansing quality was assessed with the Boston Bowel Preparation Scale (BBPS). Results. The median GRV in the split-dose group (17 ml, with a range of 0–50 ml; N=65) was significantly lower than that in the single-dose group (22 ml, with a range of 0–62 ml; N=64; p=0.005), with a better bowel cleansing quality (BBPS score 8.05±0.82 versus 7.64±1.21; p=0.028). GRV was not associated with diabetes or the use of medications. Conclusions. GRV after a split-dose preparation and fasting for 2–4 hours is not larger than that after a conventional single-dose preparation and fasting for 6–8 hours. The data indicates that the split-dose bowel preparation might not increase the risk of aspiration.

Quality and effect of single dose versus split dose of polyethylene glycol bowel preparation for early-morning colonoscopy

Endoscopy ◽  
2007 ◽  
Vol 39 (07) ◽  
pp. 616-619 ◽  
Author(s):  
J. Park ◽  
C. Sohn ◽  
S. Hwang ◽  
H. Choi ◽  
J. Park ◽  
...  
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Early Morning ◽  
Split Dose

A Single or Split Dose Picosulphate/Magnesium Citrate Before Colonoscopy: Comparison Regarding Tolerance and Eficacy with Polyethylene Glycol. A Randomized Trial

2014 ◽  
Vol 23 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Vladimir Kojecky ◽  
Jiri Dolina ◽  
Bohuslav Kianicka ◽  
Miroslav Misurec ◽  
Michal Varga ◽  
...  
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Magnesium Citrate ◽  
Split Dose ◽  
Sodium Picosulphate ◽  
Solution Type ◽  
Bowel Cleansing ◽  
Significant Difference ◽  
Colonic Preparation

Background & Aims: To compare the eficacy and tolerance of sodium picosulphate/magnesium citrate(PMC) and polyethylene glycol (PEG) in a single or split dose regimen for colonoscopy bowel preparation.Methods: A prospective, randomized, endoscopist-blinded, multicenter study. The patients were randomly assigned to receive PMC (PMC4/0) or PEG (PEG4/0) in a single dose 4L day before colonoscopy or a split dose 2+2L PMC (PMC2/2) or 3+1L PEG (PEG3/1) one day before and in the morning before the colonoscopy. Each patient was interviewed to determine his/her subjective tolerance of the preparation before the procedure. The quality of bowel cleansing was assessed in a blinded test performed by multiple endoscopists using the Aronchick scale.Results: A total of 600 patients were enrolled, 88.2% were included in the analysis. Satisfactory bowel cleansing (Aronchick score 1 and 2) was signicantly more frequent when a split dose was used irrespective of the solution type (81.6% PMC2/2, 87.3% PEG3/1 vs. 73.0% PEG4/0, p = 0.024). In single dose regimens, PMC performed better than PEG (82.6% vs. 73.0%). Single or split dose PMC preparations were comparable. A PMC based solution was generally better tolerated than PEG regardless of the regimen used (p < 0.001). Nausea was reported mostly after the 4L PEG (32.8%, p < 0.001), incontinence after a split PMC dose (34.4%, p = 0.002), and bloating after the 4L PEG (38.0%, p < 0.001). There was no significant difference in the prevalence of vomiting.Conclusion: Colonic preparation with PMC yields similar results as a split PEG dose, regardless of whether PMC is administered in single or separate doses. PMC is better tolerated than any PEG-based preparation. A single 4L PEG the day before the colonoscopy is less appropriate for bowel cleansing.

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