Histomorphometric and collagen fibers organization in annular punctured induced intervertebral disc degeneration in rabbit model: restorative and antioxidant role of Brassica oleracea

2021 ◽  
Author(s):  
B. Ogunlade ◽  
S. A. Adelakun ◽  
B. K. Akinola ◽  
O. A. Adedotun
Keyword(s):  
Intervertebral Disc ◽  
Brassica Oleracea ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Rabbit Model ◽  
Collagen Fibers

scholarly journals Role of the miR-133a-5p/FBXO6 axis in the regulation of intervertebral disc degeneration

2021 ◽  
Vol 29 ◽  
pp. 123-133
Author(s):  
Xian-Fa Du ◽  
Hai-Tao Cui ◽  
He-Hai Pan ◽  
Jun Long ◽  
Hao-Wen Cui ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration

scholarly journals Effect of the adenovirus-mediated Wip1 gene on lumbar intervertebral disc degeneration in a rabbit model

2017 ◽  
Vol 16 (6) ◽  
pp. 9487-9493 ◽  
Author(s):  
Yuan Wang ◽  
Yong Yang ◽  
Jing-Chuan Sun ◽  
Qin-Jie Kong ◽  
Hai-Bo Wang ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Rabbit Model ◽  
Lumbar Intervertebral Disc

Role of autophagy in intervertebral disc degeneration

2021 ◽  
Author(s):  
Rebecca Kritschil ◽  
Melanie Scott ◽  
Gwendolyn Sowa ◽  
Nam Vo
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration

Genetic aspects of intervertebral disc degeneration

2015 ◽  
Vol 26 (5) ◽  
pp. 581-606 ◽  
Author(s):  
Sara Hanaei ◽  
Sina Abdollahzade ◽  
Alireza Khoshnevisan ◽  
Christopher K. Kepler ◽  
Nima Rezaei
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Genetic Factors ◽  
Wide Spectrum ◽  
Nucleotide Polymorphisms ◽  
Disc Disease ◽  
Multifactorial Diseases ◽  
Common Causes

AbstractIntervertebral disc degeneration (IVDD) is one of the common causes of low back pain. Similar to many other multifactorial diseases, it is affected by environmental and genetic factors. Although not completely understood, genetic factors include a wide spectrum of variations, such as single nucleotide polymorphisms, which could play a significant role in the etiology of this disease. Besides, the interactions with environmental factors could make the role of genetic factors more complicated. Genetic variations in disc components could participate in developing degenerative disc disease through altering the normal homeostasis of discs. Gene polymorphisms in disc proteins (collagens I, II, III, IX, and XI), proteoglycans (aggrecan), cytokines (interleukins I, VI, and X), enzymes (matrix metalloproteinases II, III, and IX), and vitamin D receptor seem to play considerable roles in the pathology of this disease. There are also many other investigated genes that could somehow take part in the process. However, it seems that more studies are needed to clarify the exact role of genetics in IVDD.

scholarly journals Potential Role of lncRNAs in Contributing to Pathogenesis of Intervertebral Disc Degeneration Based on Microarray Data

2015 ◽  
Vol 21 ◽  
pp. 3449-3458 ◽  
Author(s):  
Yu Chen ◽  
Haijian Ni ◽  
Yingchuan Zhao ◽  
Kai Chen ◽  
Ming Li ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Microarray Data ◽  
Intervertebral Disc Degeneration ◽  
Potential Role
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