scholarly journals Coincidental SARS-CoV-2 infection and mRNA vaccination: a case report addressing the most important clinical questions

Infection ◽  
2021 ◽  
Author(s):  
Ozan E. Eren ◽  
Matthias Tonon ◽  
Florian Schöberl ◽  
Clemens Gießen-Jung ◽  
Andreas Moosmann ◽  
...  

AbstractThe case describes the coincidental mRNA vaccination and SARS-CoV-2 infection of a 31-year-old physician addressing the theoretical considerations and recommendations for further actions in such a particular constellation that we will expect more often in the near future.

1989 ◽  
Vol 20 (03) ◽  
pp. 170-172 ◽  
Author(s):  
B.J. Ansink ◽  
H. Sarphatie ◽  
H. van Dongen

2019 ◽  
Vol 49 (1) ◽  
pp. 85
Author(s):  
Dini Widiarni Widodo ◽  
Hemastia Manuhara Harba'i

Background: Preauricular fistula is a congenital malformation of the six auditory hillocks during the development of auricle, when an imperfect fusion of the first arch tuberculum to other tuberculums occurred and generated a tract. It is characterized by a nodule or a dent located adjacent to the external ear. An infection will create a swollen area in front of ear auricles with pain and suppuration. Fistula extirpation should be carried out after the acute infection subsides. Purpose: To evaluate surgery techniques with the lowest complication and recurrence rate. Case report: Reporting 4 surgical cases of prearicular fistula treated by Plastic-Reconstructive ENT Head and Neck surgery, among 26 cases of preauricular fistula diagnosed between 2015 to 2017 in Cipto Mangunkusumo General Hospital. Methods: Searching literature through Pubmed, Wiley, Proquest and Google Schoolar with keywords of “Preauricular fistula AND surgical treatment”. Further selection through clinical questions. Results: One journal presented a systematic review on the surgical outcome of preauricular sinus excision techniques. Reporting 4 cases treated by plastic-reconstructive surgery based on the systematic review above mentioned. Conclusion: The supra auricular approach could be recommended as a good technique for preauricular fistula, in particular for the infected and/or the recurrent cases. Latar belakang: Fistel preaurikula adalah suatu kelainan malformasi kongenital, dimana tuberkulum arkus brakialis pertama tidak menyatu dengan tuberkulum lainnya, sehingga terbentuk sebuah traktus (saluran). Fistel preaurikula ditandai oleh adanya nodul atau cekungan yang tampak di dekat telinga luar. Bila terjadi infeksi biasanya menyebabkan daerah di depan daun telinga bengkak dan nyeri, serta bernanah. Ekstirpasi fistel sebaiknya dilakukan setelah infeksi akut mereda. Tujuan: Mengevaluasi teknik bedah dengan tingkat komplikasi dan kekambuhan terendah. Laporan kasus: Dilaporkan 4 kasus fistel preaurikula yang ditatalaksana oleh bedah THT-KL plastik-rekonstruksi, dari sejumlah 26 kasus yang datang berobat di RSUPN Cipto Mangunkusumo, antara Januari 2015 dan April 2017. Metode: Penelitian literatur melalui Pubmed, Wiley, Proquest, dan Google Schoolar dengan kata kunci “Preauricular fistula AND surgery treatment”. Seleksi literatur lebih lanjut melalui pertanyaan klinis. Hasil: Didapati 1 jurnal yang menyajikan hasil operasi dari teknik bedah eksisi sinus preaurikular secara systematic review. Dilaporkan 4 kasus yang ditatalaksana dengan bedah plastik-rekonstruksi berdasarkan systematic review tersebut di atas. Kesimpulan: Pendekatan supra aurikula dapat direkomendasikan sebagai teknik bedah yang baik untuk penatalaksanaan fistel preaurikular, khususnya yang terinfeksi dan/atau berulang.


2020 ◽  
Vol 7 (2) ◽  
pp. 109-128
Author(s):  
Nur-E-Alam Rasel ◽  
Md. Sofiqul Alam ◽  
Md. Mostafizur Rahman Siddique ◽  
Narottam Debnath ◽  
Md. Jahangir Alam ◽  
...  

Most pituitary adenomas are slow-growing and benign, which means they are not cancer and do not spread to other parts of the body. They generally have a slow but severe impact on vision due to compression of the optic nerves, optic chiasm, and cavernous sinus.  However, as they grow big they can put pressure on nearby structures, such as the nerves that connect the eyes to the brain and cause symptoms. Pituitary adenomas are the third most common intracranial tumor and arise from the pituitary gland. An individual case is presented in this paper with radiological evidence (MRI) of a large lobulated intrasellar mass (3.0 cm transversely, 3.5 cm craniocaudally and 2 cm anteroposteriorly) with supra-sellar extension is causing elevation of the floor of the 3rd ventricle of the brain. Pituitary macroadenoma and hemorrhagic foei, pituitary apoplexy, and pituitary adenomas were founded by different CT scan and MRI reports in different laboratories. The patient was treated with constitutional homoeopathic medicines – Natrum muriticum-m/1, 16 doses up to Natrum muriticum-m/20, 16 doses each from 26/04/2014 to 07/08/2017. Before treatment imaging was done several times from 6/04/2011 to 12/01/2012showed complete resolution of the pituitary adenoma and during treatment3 follow-up imaging was done on 25/07/2015 and 06/08/2017. This case report reviews the clinical presentation, homoeopathic management, and treatment of the major classification of pituitary adenomas and call attention to the need for repertorization in individualized homoeopathic prescription. It is hoped that if this type of clinical research continues in the future, homeopathy will have a breakthrough result and it’s symptomatic medical treatment will play a beneficial role in the near future from the deadly evils of various types of chemotherapy, radiotherapy, or combined therapy.


2020 ◽  
Vol 62 (3) ◽  
pp. 333 ◽  
Author(s):  
Sandeep Grover ◽  
Seema Rani ◽  
Swapnajeet Sahoo ◽  
Shaheena Parveen ◽  
Aseem Mehra ◽  
...  
Keyword(s):  

2010 ◽  
Vol 39 ◽  
pp. 19-24 ◽  
Author(s):  
Ling Li Fu ◽  
Tao Chen

With more clinical trials using electronic way, new drugs electronic application has becoming an inevitable trend in near future. A well-designed case report form (CRF) is the premise of high quality clinical trials which facilitates data collection and entry, and directly benefits other facets of clinical data management. Firstly, paper introduces the CRF design modes and design principles. Then paper describes the CRF design process, and based on this, paper constructs the data structure with CDISC ODM concept. Lastly, paper explores how to convert the paper CRF to electronic format in web application with SAS statistic requirements in detail.


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