Authors’ Reply to Uysal and Colleagues’ Comment on: “Evaluation of Potential Drug–Drug Interactions in Adults in the Intensive Care Unit: A Systematic Review and Meta-Analysis”

Drug Safety ◽  
2020 ◽  
Vol 43 (2) ◽  
pp. 195-196 ◽  
Author(s):  
Adrian Wong ◽  
Mary Grace Fitzmaurice ◽  
Pamela L. Smithburger ◽  
Mitchell S. Buckley ◽  
Sandra L. Kane-Gill
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Drug Interactions ◽  
Meta Analysis ◽  
Potential Drug

Evaluation of Potential Drug–Drug Interactions in Adults in the Intensive Care Unit: A Systematic Review and Meta-Analysis

Drug Safety ◽  
2019 ◽  
Vol 42 (9) ◽  
pp. 1035-1044 ◽  
Author(s):  
Mary Grace Fitzmaurice ◽  
Adrian Wong ◽  
Hannah Akerberg ◽  
Simona Avramovska ◽  
Pamela L. Smithburger ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Drug Interactions ◽  
Meta Analysis ◽  
Potential Drug

scholarly journals Comment on “Evaluation of Potential Drug–Drug Interactions in Adults in the Intensive Care Unit: A Systematic Review and Meta-analysis”

Drug Safety ◽  
2020 ◽  
Vol 43 (2) ◽  
pp. 193-193
Author(s):  
Nusret Uysal ◽  
Elif Keskin-Arslan ◽  
Hilal Erol ◽  
Selin Acar ◽  
Yusuf Cem Kaplan
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Drug Interactions ◽  
Meta Analysis ◽  
Potential Drug

scholarly journals Safety and efficacy of routine diagnostic test reduction interventions in patients admitted to the intensive care unit: A systematic review and meta-analysis

2021 ◽  
Vol 49 (1) ◽  
pp. 23-34
Author(s):  
Katherine P Hooper ◽  
Matthew H Anstey ◽  
Edward Litton
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Meta Analysis ◽  
Diagnostic Testing ◽  
Intervention Group ◽  
Cochrane Central Register ◽  
Safety And Efficacy ◽  
Significant Difference

Reducing unnecessary routine diagnostic testing has been identified as a strategy to curb wasteful healthcare. However, the safety and efficacy of targeted diagnostic testing strategies are uncertain. The aim of this study was to systematically review interventions designed to reduce pathology and chest radiograph testing in patients admitted to the intensive care unit (ICU). A predetermined protocol and search strategy included OVID MEDLINE, OVID EMBASE and the Cochrane Central Register of Controlled Trials from inception until 20 November 2019. Eligible publications included interventional studies of patients admitted to an ICU. There were no language restrictions. The primary outcomes were in-hospital mortality and test reduction. Key secondary outcomes included ICU mortality, length of stay, costs and adverse events. This systematic review analysed 26 studies (with more than 44,00 patients) reporting an intervention to reduce one or more diagnostic tests. No studies were at low risk of bias. In-hospital mortality, reported in seven studies, was not significantly different in the post-implementation group (829 of 9815 patients, 8.4%) compared with the pre-intervention group (1007 of 9848 patients, 10.2%), (relative risk 0.89, 95% confidence intervals 0.79 to 1.01, P = 0.06, I2 39%). Of the 18 studies reporting a difference in testing rates, all reported a decrease associated with targeted testing (range 6%–72%), with 14 (82%) studies reporting >20% reduction in one or more tests. Studies of ICU targeted test interventions are generally of low quality. The majority report substantial decreases in testing without evidence of a significant difference in hospital mortality.

Effect of earplugs and eye masks on the sleep quality of intensive care unit patients: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Chiu‐Shu Fang ◽  
Hsiu‐Hung Wang ◽  
Ruey‐Hsia Wang ◽  
Fan‐Hao Chou ◽  
Shih‐Lun Chang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Sleep Quality ◽  
Meta Analysis

Apnoeic oxygenation during intubation in the intensive care unit: A systematic review and meta-analysis

Heart & Lung ◽  
2017 ◽  
Vol 46 (6) ◽  
pp. 452-457 ◽  
Author(s):  
Matthew J. Binks ◽  
Rhys S. Holyoak ◽  
Thomas M. Melhuish ◽  
Ruan Vlok ◽  
Anthony Hodge ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Meta Analysis ◽  
Apnoeic Oxygenation

scholarly journals Disease burden of intensive care unit-acquired pneumonia in China: a systematic review and meta-analysis

2014 ◽  
Vol 29 ◽  
pp. 84-90 ◽  
Author(s):  
Yaowen Zhang ◽  
Zhiyuan Yao ◽  
Siyan Zhan ◽  
Zhirong Yang ◽  
Dong Wei ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Disease Burden ◽  
Meta Analysis
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