Bilateral Fetal Hydronephrosis presenting with Complete Penoscrotal Transposition at Birth: What to tell the Prospective Parents?

Postnatal ultrasound follow-up in neonates with prenatal hydronephrosis

Diagnosis ◽

10.1515/dx-2020-0109 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Elham Kebriyaei ◽

Ali Davoodi ◽

Seyed Alinaghi Kazemi ◽

Zahra Bazargani

Keyword(s):

Ultrasound Imaging ◽

Maternal Education ◽

Left Kidney ◽

Ultrasound Images ◽

Fetal Ultrasound ◽

Renal Anomalies ◽

Cross Sectional ◽

Fetal Hydronephrosis ◽

Kidney Involvement

Abstract Objectives Renal anomalies are the most common fetal abnormalities that occur during prenatal development, and are typically detected by observing hydronephrosis on fetal ultrasound imaging. Follow-up with post-natal ultrasound is important to detect clinically-important obstruction, because many of the pre-natal abnormalities resolve spontaneously. This study aimed to evaluate the postnatal hydronephrosis follow-up rate, and reasons for non follow-up in affected neonates. Methods In this cross-sectional study all neonates born during a period of one year at Ayatollah Mousavi Hospital with hydronephrosis on fetal ultrasound imaging were recruited. All mothers were also given face-to-face information about fetal hydronephrosis and its postnatal outcomes, and follow-up with at least a postnatal ultrasound was recommended from the fourth day of their neonates’ birth until the end of the fourth week. The neonates were subsequently observed for one month to determine the postnatal ultrasound follow-up rate and to reflect on diagnostic test results, reasons for failure to follow-up, as well as causes of hydronephrosis. Results In this study, 71 cases (1.2%) out of 5,952 neonates had fetal hydronephrosis on prenatal ultrasound images. The postnatal ultrasound imaging showed kidney involvement in 18 neonates (25%), particularly in the left kidney (61.1%). Seven neonates had no follow-up at one month (10%). No significant relationship was found between lack of follow-up and the neonates’ place of residence (p=0.42), maternal education (p=0.90), number of siblings (p=0.33), or gender (p=0.64). Conclusions Postnatal ultrasound follow-up rate in these neonates with a history of fetal hydronephrosis was incomplete even though parents had been provided with education and advice at their birth time. Accordingly, it is recommended to perform postnatal ultrasound once neonates are discharged from hospitals.

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Increased nuchal translucency after low risk noninvasive prenatal testing: What should we tell the prospective parents?

Prenatal Diagnosis ◽

10.1002/pd.6024 ◽

2021 ◽

Author(s):

Joanne Kelley ◽

George McGillivray ◽

Simon Meagher ◽

Lisa Hui

Keyword(s):

Prenatal Testing ◽

Nuchal Translucency ◽

Low Risk ◽

Noninvasive Prenatal Testing ◽

Increased Nuchal Translucency ◽

Prospective Parents

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P08.08: Correlation of prenatal renal parenchymal thickness with postnatal outcome of severe fetal hydronephrosis

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.14144 ◽

2014 ◽

Vol 44 (S1) ◽

pp. 228-228

Author(s):

H. Cho ◽

Y. Kim ◽

Y. Park ◽

J.E. Kwon

Keyword(s):

Fetal Hydronephrosis ◽

Postnatal Outcome ◽

Parenchymal Thickness

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Angiographic demonstration of an aberrant abdominal umbilical artery in a patient with penoscrotal transposition and caudal regression

Surgical and Radiologic Anatomy ◽

10.1007/s00276-008-0411-9 ◽

2008 ◽

Vol 31 (3) ◽

pp. 215-219 ◽

Cited By ~ 2

Author(s):

Brian J. Dillon ◽

Ahmad I. Alomari

Keyword(s):

Umbilical Artery ◽

Caudal Regression ◽

Angiographic Demonstration ◽

Penoscrotal Transposition

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Preconception expanded carrier screening: a focus group study with relatives of mucopolysaccharidosis type III patients and the general population

Journal of Community Genetics ◽

10.1007/s12687-021-00519-2 ◽

2021 ◽

Author(s):

Thirsa Conijn ◽

Ivy van Dijke ◽

Lotte Haverman ◽

Phillis Lakeman ◽

Frits A Wijburg ◽

...

Keyword(s):

General Population ◽

Focus Groups ◽

Autosomal Recessive Disorder ◽

Carrier Screening ◽

Test Results ◽

Focus Group Study ◽

Expanded Carrier Screening ◽

Preconception Expanded Carrier Screening ◽

Mps Iii ◽

Prospective Parents

AbstractPreconception expanded carrier screening (ECS) enables prospective parents to assess their risk of having a child with an autosomal recessive disorder. Knowledge on motivations, feelings, and considerations people have towards the offer and use of ECS is limited. To enrich the public and professional discussion on ECS implementation, this study explored the perspectives towards various aspects of ECS in seven focus groups compromising first- and second-degree relatives of MPS III patients (N=9, N=4, N=5, N=5) and members of the general Dutch population (N=6, N=7, N=5). The focus groups were audio recorded and the transcripts were qualitatively analyzed to identify themes. Both relatives of MPS III patients and participants from the general population supported offering ECS, in particular for severe, childhood-onset disorders. Important barriers identified for ECS were a lack of genetic knowledge and a perceived lack of personal relevance and awareness, as well as out-of-pocket costs of testing. The majority of participants would prefer full disclosure of individual test results instead of couple-based test results. Moreover, offering people a choice for the way of reporting was proposed. All participants agreed that more efforts, for example by governmental campaigns, should be made to increase awareness on the availability, potentials, and limitations of ECS. Educating prospective parents about ECS is essential for increasing awareness and informed decision making. This study provides valuable insights that can be used by governments and public health authorities when considering implementation of preconception ECS.

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