scholarly journals Synthesis of atomic platinum with high loading on metal-organic sulfide

Author(s):  
Lijun Yang ◽  
Jingwen Bai ◽  
Wengang Liu ◽  
Xiaonan Kan ◽  
Gang Lin ◽  
...  
2020 ◽  
Vol 8 (3) ◽  
pp. 163-190
Author(s):  
Benjamin Steinborn ◽  
Ulrich Lächelt

: Coordinative interactions between multivalent metal ions and drug derivatives with Lewis base functions give rise to nanoscale coordination polymers (NCPs) as delivery systems. As the pharmacologically active agent constitutes a main building block of the nanomaterial, the resulting drug loadings are typically very high. By additionally selecting metal ions with favorable pharmacological or physicochemical properties, the obtained NCPs are predominantly composed of active components which serve individual purposes, such as pharmacotherapy, photosensitization, multimodal imaging, chemodynamic therapy or radiosensitization. By this approach, the assembly of drug molecules into NCPs modulates pharmacokinetics, combines pharmacological drug action with specific characteristics of metal components and provides a strategy to generate tailorable multifunctional nanoparticles. This article reviews different applications and recent examples of such highly functional nanopharmaceuticals with a high ‘material economy’. : Lay Summary: Nanoparticles, that are small enough to circulate in the bloodstream and can carry cargo molecules, such as drugs, imaging or contrast agents, are attractive materials for pharmaceutical applications. A high loading capacity is a generally aspired parameter of nanopharmaceuticals to minimize patient exposure to unnecessary nanomaterial. Pharmaceutical agents containing Lewis base functions in their molecular structure can directly be assembled into metal-organic nanopharmaceuticals by coordinative interaction with metal ions. Such coordination polymers generally feature extraordinarily high loading capacities and the flexibility to encapsulate different agents for a simultaneous delivery in combination therapy or ‘theranostic’ applications.


2019 ◽  
Vol 10 (18) ◽  
pp. 2263-2272 ◽  
Author(s):  
Huaizhi Liu ◽  
Hao Peng ◽  
Yumeng Xin ◽  
Jiuyang Zhang

We reported for the first time using metal–organic framework (MOF) nanoparticles as effective nanofillers to significantly enhance the mechanical performance of hydrogels. The MOF hydrogels have been developed for drug delivery materials with high loading capacity and much extended drug releasing profiles.


2018 ◽  
Vol 6 (8) ◽  
pp. 3402-3413 ◽  
Author(s):  
Zhishang Li ◽  
Guanshan Zhou ◽  
Huang Dai ◽  
Mingying Yang ◽  
Yingchun Fu ◽  
...  

The efficient incorporation of porous materials into membranes to prepare hybrid membranes for the development of a separation device for water pollution treatment is described.


2020 ◽  
Vol 56 (89) ◽  
pp. 13848-13851
Author(s):  
Yulu Zhu ◽  
Wei Du ◽  
Qilong Zhang ◽  
Hui Yang ◽  
Quan Zong ◽  
...  

A core–shell array electrode displays high areal capacity and rate capability with a highly conductive framework and a high loading of active materials.


2016 ◽  
Vol 30 (11) ◽  
pp. 954-958 ◽  
Author(s):  
Sadegh Rostamnia ◽  
Hassan Alamgholiloo ◽  
Maryam Jafari ◽  
Rezan Rookhosh ◽  
Amir Reza Abbasi

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