Bioprosthetic tricuspid valve stenosis associated with extensive plaque deposition in carcinoid heart disease

1991 ◽  
Vol 121 (6) ◽  
pp. 1835-1838 ◽  
Author(s):  
Paul M Ridker ◽  
Glenn M Chertow ◽  
Elizabeth W Karlson ◽  
Andrew S Neish ◽  
Frederick J Schoen
Keyword(s):  
Heart Disease ◽  
Tricuspid Valve ◽  
Carcinoid Heart Disease ◽  
Plaque Deposition ◽  
Tricuspid Valve Stenosis

Case of calcific tricuspid and pulmonary valve stenosis

2020 ◽  
Vol 13 (9) ◽  
pp. e235190
Author(s):  
Yash Paul Sharma ◽  
Prashant Kumar Panda ◽  
Lipi Uppal ◽  
Uma Debi
Keyword(s):  
Heart Disease ◽  
Tricuspid Valve ◽  
Valvular Heart Disease ◽  
Pulmonary Valve ◽  
Carcinoid Heart Disease ◽  
Pulmonary Valve Stenosis ◽  
Almost All ◽  
Unusual Finding ◽  
Severe Calcification ◽  
Tricuspid Valve Stenosis

Isolated right-sided valvular disease is a much less recognised entity when compared with left-sided valvular heart disease. Almost all the cases of combined pulmonary valve with tricuspid valve involvement are a consequence of underlying carcinoid heart disease. Moreover, severe calcification of tricuspid valve is an extremely unusual finding. We report a case of a severe calcific tricuspid valve stenosis along with severe pulmonary valve stenosis where the exact aetiology could not be established. On reviewing the literature, we did not find any reports describing such a morphology.

scholarly journals Outcomes after Tricuspid Valve Replacement for Carcinoid Heart Disease: A Multicenter Study

2020 ◽  
Vol 4 (2) ◽  
pp. 122-130
Author(s):  
Kevin M. Veen ◽  
Einar A. Hart ◽  
Mostafa M. Mokhles ◽  
Peter L. de Jong ◽  
Frederiek de Heer ◽  
...  
Keyword(s):  
Heart Disease ◽  
Valve Replacement ◽  
Tricuspid Valve ◽  
Multicenter Study ◽  
Carcinoid Heart Disease ◽  
Tricuspid Valve Replacement

scholarly journals 1640 Pulmonary valve in carcinoid disease: be suspicious of functional assessment

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A L Gamarra Lobato ◽  
A M Rojas ◽  
A Cecconi ◽  
L Dominguez ◽  
A Benedicto ◽  
...  
Keyword(s):  
Heart Disease ◽  
Right Ventricle ◽  
Tricuspid Valve ◽  
Functional Assessment ◽  
Carcinoid Syndrome ◽  
Pulmonary Valve ◽  
Previous History ◽  
Pulmonary Regurgitation ◽  
Lower Limbs ◽  
Carcinoid Heart Disease

Abstract Carcinoid heart disease occurs in 50% of patients with carcinoid syndrome, especially on serotonin-secreting neuroendocrine tumors (NET) [1, 2]. Carcinoid heart disease"s typical findings are carcinoid plaques, composed of smooth muscle, myofibroblasts and endothelium. These plaques, most frequently localized on the right side valvular cusps and leaflets, produce fixation and retraction, causing regurgitation and/or stenosis [3, 4, 5]. Left-sided heart disease is rare (<10%), as serotonin is purified in the pulmonary circulation [3, 6, 7]. We present the case of a 67 year old female patient with previous history of right ovarian NET. She presented with dyspnea (II-III NYHA functional class), and slight edema in lower limbs. She denied symptoms of carcinoid syndrome before or after the ovarian surgery. Examination showed an increased jugular venous pulse. Transthoracic echocardiography (TTE) showed severely dilated right cavities and a rigid, immobile tricuspid valve, with massive tricuspid regurgitation (Panel A, 1). Anatomy of pulmonary valve was not properly visualized but jet area of pulmonary regurgitation was small (Panel A, 2). Left cavities and valves were intact. As TTE was not anatomically conclusive, a cardiac magnetic resonance (CMR) and a cardiac computed tomography (CCT) were performed to assess the carcinoid involvement of pulmonary valve. CMR showed severely dilated right ventricle with mild impairment of systolic function (Panel A, 3). Based on phase contrast imaging, pulmonary regurgitation fraction was 14%, suggestive of a mild grade. However, CCT showed a diffuse thickening of the pulmonary valve, with complete opening during diastole (Panel A, 4, arrowhead). Finally, the patient underwent replacement of tricuspid valve and pulmonary valve for biological prosthesis without complications. Our case is remarkable because it highlights the limitations of the functional assessment of pulmonary regurgitation in the presence of a concomitant massive tricuspid valve regurgitation, since the rapid equalization of pressure between pulmonary artery and right ventricle reduces the expression of pulmonary regurgitation. For these reason, the anatomic assessment of the pulmonary valve is mandatory to stage the involvement of pulmonary valve in carcinoid disease. Abstract 1640 Figure. Panel A

scholarly journals “Locked Tricuspid Valve” in Carcinoid Heart Disease

2020 ◽  
Vol 85 (1) ◽  
pp. 78
Author(s):  
Ayako Sekine ◽  
Takatomo Watanabe ◽  
Genki Naruse ◽  
Ayae Takada ◽  
Shingo Fujimoto ◽  
...  
Keyword(s):  
Heart Disease ◽  
Tricuspid Valve ◽  
Carcinoid Heart Disease

scholarly journals Bioprosthetic Pulmonary and Tricuspid Valve Replacement in Carcinoid Heart Disease From Ovarian Primary Cancer

2009 ◽  
Vol 73 (8) ◽  
pp. 1554-1556 ◽  
Author(s):  
Hiroaki Takahashi ◽  
Kenji Okada ◽  
Mitsuru Asano ◽  
Masamichi Matsumori ◽  
Yoshihisa Morimoto ◽  
...  
Keyword(s):  
Heart Disease ◽  
Valve Replacement ◽  
Tricuspid Valve ◽  
Carcinoid Heart Disease ◽  
Primary Cancer ◽  
Tricuspid Valve Replacement

scholarly journals Cardiac Magnetic Resonance for Diagnosis of Neuroendocrine Tumor Metastases to the Right and Left Ventricles with Carcinoid Heart Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Daniel Barnebee ◽  
Brian Morse ◽  
Jonathan R. Strosberg ◽  
Marijan Pejic ◽  
Daniel Jeong
Keyword(s):  
Heart Disease ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Neuroendocrine Tumor ◽  
Tricuspid Valve ◽  
Hepatic Metastases ◽  
Tumor Burden ◽  
Left Ventricular ◽  
Carcinoid Heart Disease ◽  
Tumor Metastases

A 76-year-old male with a small bowel neuroendocrine tumor with hepatic metastases presented with new onset lower extremity swelling, bloating, and weight gain which ultimately lead to cardiac magnetic resonance (CMR) to evaluate for cardiac involvement of disease. CMR showed right and left ventricular myocardial metastases along with findings suggestive of carcinoid heart disease. The patient had severe tricuspid valve regurgitation necessitating surgical valve repair. The patient underwent bioprosthetic tricuspid valve replacement and debulking of the metastases with surgical pathology confirming neuroendocrine tumor metastases. Follow-up clinical evaluations at 3, 6, and 9 months postoperatively showed improvement in cardiac function and stable hepatic tumor burden. This case demonstrates the utility of CMR to diagnose myocardial metastases and carcinoid heart disease complicated by severe tricuspid regurgitation, which guided surgical management.

scholarly journals P225 Carcinoid heart disease: report of a case in a patients with trombocytopenia absent radius

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
M Quezada ◽  
R Ayala ◽  
M Ramos ◽  
Z Villa Benayas ◽  
M Calderon-Dominguez ◽  
...  
Keyword(s):  
Heart Disease ◽  
Tricuspid Valve ◽  
Tricuspid Regurgitation ◽  
Carcinoid Syndrome ◽  
Clinical Manifestations ◽  
Somatostatin Analogues ◽  
Carcinoid Heart Disease ◽  
Delay In Diagnosis ◽  
Bilateral Absence ◽  
Absent Radius

Abstract Background The carcinoid syndrome is characterized by extensive and several clinical manifestations. The diarrhea, the cutaneous flushing are the most frequents symptoms while cardiac manifestations (carcinoid heart disease) (CHD) occurs in a mean of 40%. Nowadays, the number of cases of CHD is lower than 20%, as a consequence of the widespread use of somatostatin analogues. At present, there is a mean delay in diagnosis of CHD of 1.5 years from the time of carcinoid syndrome detection. Hence, CHD is associated with a poor prognosis for clinical management. Case report We present a case of 45-years-old active woman, with Thrombocytopenia absent radius (TAR). This is characterized by a bilateral absence of the radio with the presence of both thumbs and thrombocytopenia. Our patient was attended for dyspnea of medium efforts, history of diarrhea, cutaneous flushing with tachycardia and elevated urinary 5-hydroxyindoleacetic acid (5-HIAA) (89,6 mg/24 (2,0-9,0)). The Transthoracic echocardiography showed morphologic changes that affected the tricuspid valve: diminished curvature of the leaflets, altered dynamic motion of the leaflets during diastole, fused and shortened chordae retraction and reduced excursion of the valve. A moderate to severe tricuspid regurgitation and tricuspid stenosis with gradient media de 5 mmHg was observed. In addition, the right ventricle was dilated, a severe pulmonary hypertension, a right pleural effusion and a minor pericardial effusion circumference were detected. All these findings were consistent with CHD. Conclusions This report describes an unusual case of CHD in TAR patient. In fact, the interest of this case is the role played by the echocardiogram in the differential diagnosis for tricuspid valve diseases. Tricuspid stenosis is an infrequent condition and it is usually related with rheumatic disease associated with mitral valve disease. Although the carcinoid syndrome is infrequent, any changes in the anatomical structure of the tricuspid valve (thickening, fibrosis and rigidity associated with stenosis and tricuspid regurgitation) should alert us to the suspicion of CHD Abstract P225 Figure.

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