Long-term follow-up of patients with common (single) ventricle after palliative surgery

1978 ◽  
Vol 41 (2) ◽  
pp. 390 ◽  
Author(s):  
Douglas S. Moodie ◽  
Abdul J. Tajik ◽  
Donald G. Ritter ◽  
W.Michael O'Fallon
Keyword(s):  
Single Ventricle ◽  
Palliative Surgery ◽  
Long Term Follow Up

Surgery of single ventricles in humanitarian practice: surgery for which patients?

2019 ◽  
Vol 29 (5) ◽  
pp. 583-588
Author(s):  
Marielle Gouton ◽  
Olivier Michel Bical ◽  
Joy Zoghbi ◽  
Régine Roussin ◽  
Vincent Lucet ◽  
...  
Keyword(s):  
Single Ventricle ◽  
Operative Mortality ◽  
Double Outlet Right Ventricle ◽  
Palliative Surgery ◽  
Long Term Follow Up ◽  
Chirurgie Cardiaque ◽  
Lost To Follow Up ◽  
Double Inlet Left Ventricle

AbstractObjectives:To analyse the feasibility and effectiveness in humanitarian practice of surgical management of children with single-ventricle heart condition.Methods:Retrospective study of children with a single ventricle, managed by the association Mécénat-Chirurgie Cardiaque since 1996, with long-term follow-up after their return home.Results:Of the 138 children in our cohort, 119 had one or more surgeries (180 procedures): palliative surgery alone (systemic-pulmonary anastomosis or banding), 41; partial cavo-pulmonary connection, 47; total cavo-pulmonary connection (mean age 8.5 years), 31. Operative mortality is 5.5%. After a mean follow-up of 5.6 years, 18 children (13%) were lost to follow-up. Survival at 10 years is 79% in children receiving surgery (palliative only, 72%; partial cavo-pulmonary connection, 77%; total cavo-pulmonary connection, 97%) versus 29% in children with no surgical intervention. The prognosis is better for tricuspid atresia and double-inlet left ventricle (86 and 83% survival at 10 years) than for double-outlet right ventricle or complete atrio-ventricular canal defect (64 and 68% at 5 years).Conclusion:The surgery of the single ventricle in humanitarian medicine allows a very satisfactory survival after one or more surgeries tending towards a total cavo-pulmonary connection as soon as possible.

Long-term follow-up after staged reconstruction or transplantation for patients with functionally univentricular heart

2004 ◽  
Vol 14 (S1) ◽  
pp. 115-126 ◽  
Author(s):  
Gil Wernovsky ◽  
Maryanne R. K. Chrisant
Keyword(s):  
Single Ventricle ◽  
Univentricular Heart ◽  
Right Heart ◽  
Long Term Follow Up ◽  
Chronic Hypoxemia ◽  
Staged Reconstruction ◽  
Right Heart Bypass

As recently as 35 years ago, children born with a functionally single ventricle were destined to a lifetime of multiple palliative operations, and disrupted growth and development. Physical signs of their cardiac disease were evidenced by chronic hypoxemia, polycythemia, clubbing, small stature, and severely reduced exercise ability. A normal lifestyle, with typical landmarks such as uninterrupted adolescence and potential childbearing, was unlikely. The successful application of right heart bypass by Fontan and Kreutzer in the early 1970s heralded an era of multiple medical and surgical breakthroughs that have systematically improved the quality of life and long-term outlook for these children.

scholarly journals Value of Follow-Up N-Terminal Probrain Natriuretic Peptide (NT-proBNP) after a Modified Fontan Procedure

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Jianbin Li ◽  
Li Ma ◽  
Minghui Zou ◽  
Wenlei Li ◽  
Xinxin Chen ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Natriuretic Peptide ◽  
Single Ventricle ◽  
Fontan Procedure ◽  
Left Ventricular ◽  
Single Ventricle Physiology ◽  
Long Term Follow Up ◽  
The Right

Objective. To assess the value of N-terminal probrain natriuretic peptide (NT-proBNP) in short-term and long-term follow-up after a modified Fontan procedure. Methods. We retrospectively enrolled children who had undergone a modified Fontan procedure in the Heart Center of Guangzhou Women and Children’s Medical Center from January 2014 to September 2020 and collected data on NT-proBNP values before bidirectional Glenn procedure, before Fontan procedure, and on 1, 3, 7, 30, 90, and 180 days and 1, 2, 3, 4, 5, and 6 year after Fontan procedure. The relationship between changes in NT-proBNP levels and the outcomes in children was analyzed. Results. A total of 108 children (78 boys and 30 girls, mean age: 54.62 ± 29.38 weeks) were included in the analysis. According to one-way analysis of variance, the left ventricular type and biventricular type of single ventricle physiology showed shorter duration on cardiopulmonary bypass during the operation and lower levels of NT-proBNP after the operation than the right ventricular type and univentricular type physiology. Conclusion. NT-proBNP is a good indicator for mid and long-term follow-up after a modified Fontan procedure. The left ventricular type and biventricular type of single ventricle physiology show better mid and long-term benefits from the modified Fontan procedure than the right ventricular type and univentricular type physiology.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

A comparison of two approaches to biofeedback treatment in children with recalcitrant constipation/encopresis. Long term follow up

2001 ◽  
Vol 120 (5) ◽  
pp. A397-A397
Author(s):  
M SAMERAMMAR ◽  
J CROFFIE ◽  
M PFEFFERKORN ◽  
S GUPTA ◽  
M CORKINS ◽  
...  
Keyword(s):  
Long Term Follow Up ◽  
Biofeedback Treatment
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