Interaction of creatine kinase with phosphorylating rabbit heart mitochondria and mitoplasts

1986 ◽  
Vol 251 (2) ◽  
pp. 558-566 ◽  
Author(s):  
Christian Vial ◽  
Olivier Marcillat ◽  
Denise Goldschmidt ◽  
Bernard Font ◽  
Denise Eichenberger
Keyword(s):  
Creatine Kinase ◽  
Rabbit Heart ◽  
Heart Mitochondria

scholarly journals Dextran strongly increases the Michaelis constants of oxidative phosphorylation and of mitochondrial creatine kinase in heart mitochondria

1998 ◽  
Vol 254 (1) ◽  
pp. 172-180 ◽  
Author(s):  
Frank Norbert Gellerich ◽  
Fanny Dorine Laterveer ◽  
Bernard Korzeniewski ◽  
Stephan Zierz ◽  
Klaas Nicolay
Keyword(s):  
Creatine Kinase ◽  
Oxidative Phosphorylation ◽  
Heart Mitochondria ◽  
Mitochondrial Creatine Kinase ◽  
Michaelis Constants

Active transport of potassium by heart mitochondria

1960 ◽  
Vol 198 (4) ◽  
pp. 847-854 ◽  
Author(s):  
Frank Ulrich
Keyword(s):  
Methylene Blue ◽  
Active Transport ◽  
Creatine Phosphate ◽  
Rabbit Heart ◽  
Potassium Transport ◽  
Heart Mitochondria ◽  
Metabolic Inhibitors ◽  
Mitochondrial Suspension ◽  
High Concentrations ◽  
Potassium Gradient

Rabbit heart mitochondria contained potassium which could not be removed with four washings of isotonic sucrose or sodium chloride at 0–4°C. Aging, increasing concentrations of potassium, and a number of metabolic poisons either partially or completely inhibited the active transport of potassium into heart mitochondria when these particles were incubated for 15 minutes in air at 37.4° in a medium to which alpha-ketoglutarate and AMP or ATP had been added. Compounds uncoupling oxidative phosphorylation—such as arsenite, 2,4-dinitrophenol, l-thyroxine, calcium chloride, dicumarol, pentachlorophenol and methylene blue—inhibited potassium transport but usually only at relatively high concentrations (10–3 m). With the exception of p-chloromercuribenzoate, neither aging nor metabolic inhibitors prevented the extrusion of water by the mitochondria in the presence of alpha-ketoglutarate and AMP or ATP. Although addition of either ATP or substrate alone to the mitochondrial suspension resulted in a significant increase in the potassium gradient, the latter was much greater when both substrate and ATP (or ADP or AMP) were added together. ADP or AMP alone caused a very slight but probably not significant increase in the potassium gradient and creatine phosphate had no effect.

Velocity of the creatine kinase reaction in the neonatal rabbit heart: role of mitochondrial creatine kinase

Biochemistry ◽  
1988 ◽  
Vol 27 (6) ◽  
pp. 2165-2172 ◽  
Author(s):  
Stanton B. Perry ◽  
John McAuliffe ◽  
James A. Balschi ◽  
Paul R. Hickey ◽  
Joanne S. Ingwall
Keyword(s):  
Creatine Kinase ◽  
Rabbit Heart ◽  
Mitochondrial Creatine Kinase ◽  
Kinase Reaction ◽  
Creatine Kinase Reaction

scholarly journals Functional development of the creatine kinase system in perinatal rabbit heart.

1991 ◽  
Vol 69 (3) ◽  
pp. 665-676 ◽  
Author(s):  
J A Hoerter ◽  
A Kuznetsov ◽  
R Ventura-Clapier
Keyword(s):  
Creatine Kinase ◽  
Rabbit Heart ◽  
Functional Development
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