Relationship between phospholipid compositions and transport activities of amino acids in Escherichia coli membrane vesicles

1977 ◽  
Vol 466 (1) ◽  
pp. 44-56 ◽  
Author(s):  
Tetsuo Ohta ◽  
Shinichi Okuda ◽  
Hajime Takahashi
1979 ◽  
Vol 57 (12) ◽  
pp. 1376-1383 ◽  
Author(s):  
A. P. Singh ◽  
P. D. Bragg

Tributyltin chloride inhibits growth and uptake of glutamine and proline into intact cells of Escherichia coli. It causes efflux of the accumulated amino acids. A pH gradient generated in intact cells and everted membrane vesicles is dissipated by this compound. These effects do not require lipoic acid but are dependent on the presence of chloride, bromide, or iodide ions. We conclude that tributyltin chloride can catalyse a transmembrane OH−–anion exchange reaction and that this is its mode of inhibition of the uptake of these amino acids. The response of proline and glutamine uptake to the inhibitor is similar and is consistent with the transport of both amino acids requiring an electrochemical gradient of protons.


1974 ◽  
Vol 249 (9) ◽  
pp. 2939-2945
Author(s):  
Hajime Hirata ◽  
Karlheinz Altendorf ◽  
Franklin M. Harold

1976 ◽  
Vol 251 (21) ◽  
pp. 6662-6666
Author(s):  
C George-Nascimento ◽  
S J Wakil ◽  
S A Short ◽  
H R Kaback

1948 ◽  
Vol 174 (2) ◽  
pp. 391-398
Author(s):  
Yutaka. Kobayashi ◽  
Marguerite. Fling ◽  
Sidney W. Fox

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