Alcohol and local anesthetic effects on Na+-dependent Ca2+ fluxes in brain synaptic membrane vesicles

1983 ◽  
Vol 32 (6) ◽  
pp. 963-969 ◽  
Author(s):  
Mary L. Michaelis ◽  
Elias K. Michaelis
Keyword(s):  
Local Anesthetic ◽  
Membrane Vesicles ◽  
Synaptic Membrane

Characteristics of Cl?-dependentl-[35S]cysteic acid transport into rat brain synaptic membrane vesicles

1990 ◽  
Vol 15 (12) ◽  
pp. 1153-1158 ◽  
Author(s):  
Yutaka Koyama ◽  
Akemichi Baba ◽  
Heitaroh Iwata
Keyword(s):  
Rat Brain ◽  
Membrane Vesicles ◽  
Cysteic Acid ◽  
Synaptic Membrane ◽  
Acid Transport

scholarly journals Demonstration of the transmembrane nature of the acetylcholine receptor by labeling with anti-receptor antibodies.

1979 ◽  
Vol 83 (2) ◽  
pp. 499-510 ◽  
Author(s):  
C B Strader ◽  
J P Revel ◽  
M A Raftery
Keyword(s):  
Acetylcholine Receptor ◽  
Protein A ◽  
Membrane Vesicles ◽  
Antigenic Determinants ◽  
Synaptic Membrane ◽  
Electron Microscope Level ◽  
Receptor Molecule ◽  
Extracellular Side ◽  
Receptor Antibodies ◽  
Cytoplasmic Side

Antibodies raised in rabbits to Triton-solubilized, purified acetylcholine receptor from Torpedo californica were used to immunospecifically label intact T. californica electroplaque membrane vesicles attached to cover slips and oriented with the extracellular face of the synaptic membrane facing outward. Hemocyanin conjugated to Protein A was then used as a marker, making the antibody binding visible at the electron microscope level. Parallel labeling experiments were performed on vesicles attached to cover slips and sheared by sonication, leaving their cytoplasmic faces fully exposed to the labeling solution. While differences in antibody populations among different rabbits were observed, antigenic determinants of the receptor were present on both faces of the membrane, with those on the extracellular side more numerous than those on the cytoplasmic side, demonstrating the transmembrane nature of the receptor molecule.

Nuclear Envelope Dynamics During Mitosis

1988 ◽  
Vol 46 ◽  
pp. 224-225
Author(s):  
Brian Burke
Keyword(s):  
Nuclear Envelope ◽  
Membrane Vesicles ◽  
Nuclear Pore ◽  
Nuclear Pore Complexes ◽  
Animal Cells ◽  
Interphase Chromosome ◽  
Lamin B ◽  
Chromosome Architecture ◽  
Complex Membrane ◽  
Pore Complexes

The nuclear envelope is a complex membrane structure that forms the boundary of the nuclear compartment in eukaryotes. It regulates the passage of macromolecules between the two compartments and may be important for organizing interphase chromosome architecture. In interphase animal cells it forms a remarkably stable structure consisting of a double membrane ouerlying a protein meshwork or lamina and penetrated by nuclear pore complexes. The latter form the channels for nucleocytoplasmic exchange of macromolecules, At the onset of mitosis, however, it rapidly disassembles, the membranes fragment to yield small vesicles and the lamina, which is composed of predominantly three polypeptides, lamins R, B and C (MW approx. 74, 68 and 65 kDa respectiuely), breaks down. Lamins B and C are dispersed as monomers throughout the mitotic cytoplasm, while lamin B remains associated with the nuclear membrane vesicles.

Local Anesthetic Action of Aqueous Extract of Citrullous Colocynthis Fruit on Rabbit Cornea

2012 ◽  
Vol 3 (4) ◽  
pp. 209-211
Author(s):  
Dr.T.Jayasree Dr.T.Jayasree ◽  
◽  
Dr Shaikh Ubedulla ◽  
Dr. Chandrasekhar Nutalapati ◽  
Naveen Aalasyam ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Local Anesthetic ◽  
Rabbit Cornea ◽  
Anesthetic Action

A Case of Takotsubo Cardiomyopathy after Injection of a Local Anesthetic Containing Epinephrine

2014 ◽  
Vol 76 (3) ◽  
pp. 222-224 ◽  
Author(s):  
Hiroko TSURU ◽  
Hiroshi UCHI ◽  
Reiko ITO ◽  
Misa NAKANO ◽  
Futoshi KODA ◽  
...  
Keyword(s):  
Takotsubo Cardiomyopathy ◽  
Local Anesthetic
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