Inhibition of bilirubin conjugation in rat liver slices by free fatty acids, with relevance to the problem of breast milk jaundice

1972 ◽  
Vol 41 ◽  
pp. 101-107 ◽  
Author(s):  
B.R. Bevan ◽  
J.B. Holton
Keyword(s):  
Fatty Acids ◽  
Breast Milk ◽  
Free Fatty Acids ◽  
Rat Liver ◽  
Liver Slices ◽  
Breast Milk Jaundice ◽  
Bilirubin Conjugation

Free Fatty Acids in the Development of Breast Milk Jaundice

1985 ◽  
Vol 4 (3) ◽  
pp. 435-440 ◽  
Author(s):  
Firooz Jalili ◽  
Cutberto Garza ◽  
Charles T. L. Huang ◽  
Buford L. Nichols
Keyword(s):  
Fatty Acids ◽  
Breast Milk ◽  
Free Fatty Acids ◽  
Breast Milk Jaundice

Breast milk jaundice; the role of lipoprotein lipase and the free fatty acids

1980 ◽  
Vol 134 (1) ◽  
pp. 35-38 ◽  
Author(s):  
A. Constantopoulos ◽  
J. Messaritakis ◽  
N. Matsaniotis
Keyword(s):  
Fatty Acids ◽  
Breast Milk ◽  
Free Fatty Acids ◽  
Lipoprotein Lipase ◽  
Breast Milk Jaundice

Effect of saturated fat diets on rat liver NADP-linked enzymes

1965 ◽  
Vol 209 (4) ◽  
pp. 773-780 ◽  
Author(s):  
Helen M. Tepperman ◽  
Jay Tepperman
Keyword(s):  
Fatty Acids ◽  
Enzyme Activity ◽  
Rat Liver ◽  
Corn Oil ◽  
Saturated Fat ◽  
Coconut Oil ◽  
Liver Slices ◽  
Fat Diets ◽  
Effect Of Feeding

The aggregate hexosemonophosphate dehydrogenase (HMPD) activity was found to be higher in livers of rats fed a diet containing saturated fat (hydrogenated coconut oil = H) for 7 days and fasted for 48 hr than it was in similarly prepared animals fed a corn oil (CO) diet. Later, a liver HMPD-increasing effect of feeding H was found in nonfasted animals. Lipogenesis (i.e., the incorporation of acetate-1-C14 into fatty acids by liver slices) was shown to be as low or lower in the H group as in the CO. Liver slices prepared from H and CO diet adapted rats were incubated with either acetate-1-C14 or palmitate-1-C14 and the extent of incorporation of C14 into individual fatty acids was measured. With both substrates more radioactivity was found in 16:1, 18:0, and 18:1 in the case of H-fed animals. It is proposed that a component of the signal for eliciting increased NADP-linked enzyme activity in the H rats was an increased rate of oxidation of NADPH attendant on monoene formation and chain lengthening.

EFFECTS OF HYPOGLYCIN A ON THE METABOLISM OF AMINO ACIDS BY LIVER SLICES

1964 ◽  
Vol 42 (1) ◽  
pp. 139-142 ◽  
Author(s):  
S. J. Patrick ◽  
L. C. Stewart
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Glutamic Acid ◽  
Rat Liver ◽  
Inhibitory Effects ◽  
Liver Slices

The effects of hypoglycin A on the metabolism of L-leucine-C14, L-alanine-C14, and L-glutamic-acid-C14 by rat liver slices have been investigated. Hypoglycin exerted markedly inhibitory effects on the conversion of leucine-C14 to fatty acid, cholesterol, and CO2. Conversion of alanine-C14 and glutamic acid-C14 to fatty acids was also inhibited by hypoglycin. No effects of hypoglycin on the conversion of C14-amino acids into protein or glycogen were demonstrated.

Regulation by Insulin and Free Fatty Acids of Pyruvate Dehydrogenase Activity in Perfused Rat Liver

1977 ◽  
Vol 5 (4) ◽  
pp. 1000-1001 ◽  
Author(s):  
DAVID L. TOPPING ◽  
M. ANWAR GOHEER ◽  
HALDANE G. COORE ◽  
PETER A. MAYES
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Dehydrogenase Activity ◽  
Rat Liver ◽  
Pyruvate Dehydrogenase ◽  
Perfused Rat Liver

Inhibition of Glycolytic Enzymes of Rat Liver and Hepatomas by Free Fatty Acids

Oncology ◽  
1976 ◽  
Vol 33 (5-6) ◽  
pp. 205-208 ◽  
Author(s):  
M.A. Lea ◽  
G. Weber ◽  
H.P. Morris
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Rat Liver ◽  
Glycolytic Enzymes

scholarly journals Free Fatty Acids Produce Insulin Resistance and Activate the Proinflammatory Nuclear Factor- B Pathway in Rat Liver

Diabetes ◽  
2005 ◽  
Vol 54 (12) ◽  
pp. 3458-3465 ◽  
Author(s):  
G. Boden ◽  
P. She ◽  
M. Mozzoli ◽  
P. Cheung ◽  
K. Gumireddy ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Free Fatty Acids ◽  
Rat Liver ◽  
Nuclear Factor ◽  
Factor B
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