Comparison of the effect of a 28-day long term therapy with the proton pump inhibitor pantoprazole with the H2-receptor antagonist ranitidine on intragastric pH in healthy human subjects

1995 ◽  
Vol 108 (4) ◽  
pp. A240 ◽  
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Human Subjects ◽  
Term Therapy ◽  
Intragastric Ph ◽  
H2 Receptor Antagonist ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Long Term Therapy

The effects of long-term therapy with proton pump inhibitors on meal stimulated gastrin

2014 ◽  
Vol 46 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Hólmfridur Helgadóttir ◽  
David C. Metz ◽  
Yu-Xiao Yang ◽  
Andrew D. Rhim ◽  
Einar S. Björnsson
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Term Therapy ◽  
Long Term Therapy

scholarly journals Iatrogenic hypomagnesemia: an underestimated clinical problem

2015 ◽  
Vol 9 (3) ◽  
pp. 287 ◽  
Author(s):  
Antonio Villa ◽  
Paolo Zanada ◽  
Adriana Pellegrino ◽  
Gabriella Nucera ◽  
Elena Martinoli ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Serum Magnesium ◽  
Concomitant Administration ◽  
Clinical Problem ◽  
Proton Pump Inhibitor Therapy ◽  
Term Therapy ◽  
Long Term Therapy ◽  
The Relationship

Hypomagnesemia is defined by having a serum magnesium level of less than 1.7 mg/dL. The magnesium balance is tightly regulated by the concerted actions of the intestine, bone and kidneys. This balance can be disturbed by a wide variety of drugs. Recently, we observed a case of severe hypomagnesemia caused by proton pump inhibitor therapy. We conducted a retrospective study of an <em>intrahospital population</em> to evaluate the prevalence of hypomagnesemia and the relationship with associated drugs. Among 181 patients with hypomagnesemia only 29 were found to have hypomagnesemia with specific causes, such as chronic diarrhea, vomiting, and so on. In the remaining patients, 120 have taken proton pump inhibitors and/or diuretics and/or metformin. Clinicians should consider proton pump inhibitors as a possible causative agent when investigating hypomagnesemia and they should be especially attentive with patients who take proton pump inhibitors, especially in cases of long-term therapy (≥1 year) and/or concomitant administration of other agents that may lower magnesium levels (<em>e.g</em>., diuretics or metformin).

Does long-term medication with a proton pump inhibitor induce a tolerance to H2 receptor antagonist?

2007 ◽  
Vol 42 (4) ◽  
pp. 275-278 ◽  
Author(s):  
Hiroshi Hashimoto ◽  
Tetsuya Kushikata ◽  
Mihoko Kudo ◽  
Kazuyoshi Hirota
Keyword(s):  
Proton Pump Inhibitor ◽  
Receptor Antagonist ◽  
Proton Pump ◽  
H2 Receptor Antagonist ◽  
H2 Receptor

Hypomagnesemia and Hypocalcemia Caused by Proton-Pump Inhibitors Long-Term Therapy

2020 ◽  
Vol 27 (6) ◽  
pp. e676-e680 ◽  
Author(s):  
Paola Cabras ◽  
Michele Anedda ◽  
Laura Caddeo ◽  
Marongiu Francesco ◽  
Mameli Antonella
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Term Therapy ◽  
Long Term Therapy

Responses of muscle mass, strength and gene transcripts to long-term heat stress in healthy human subjects

2010 ◽  
Vol 111 (1) ◽  
pp. 17-27 ◽  
Author(s):  
Katsumasa Goto ◽  
Hideshi Oda ◽  
Hidehiko Kondo ◽  
Michihito Igaki ◽  
Atsushi Suzuki ◽  
...  
Keyword(s):  
Heat Stress ◽  
Muscle Mass ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Gene Transcripts
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