Ischaemic disease in men and women with familial hypercholesterolaemia and xanthomatosis A comparative study of genetic and environmental factors in 274 heterozygous cases

1976 ◽  
Vol 24 (3) ◽  
pp. 441-450 ◽  
Author(s):  
V. Beaumont ◽  
B. Jacotot ◽  
J.-L. Beaumont
Keyword(s):  
Environmental Factors ◽  
Comparative Study ◽  
Familial Hypercholesterolaemia ◽  
Men And Women ◽  
Genetic And Environmental Factors

Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia

2005 ◽  
Vol 15 (4) ◽  
pp. 219-225 ◽  
Author(s):  
George Miltiadous ◽  
Stavroulla Xenophontos ◽  
Eleni Bairaktari ◽  
Manolis Ganotakis ◽  
Marios Cariolou ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Statin Therapy ◽  
Familial Hypercholesterolaemia ◽  
Factors Affecting ◽  
Genetic And Environmental Factors

scholarly journals Sex Differences in Genetic and Environmental Factors Contributing to Body-Height

Twin Research ◽  
2001 ◽  
Vol 4 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Karri Silventoinen ◽  
Jaakko Kaprio ◽  
Eero Lahelma ◽  
Richard J. Viken ◽  
Richard J. Rose
Keyword(s):  
Sex Differences ◽  
Environmental Factors ◽  
Environmental Stress ◽  
Genetic Factors ◽  
Body Height ◽  
Men And Women ◽  
Cohort Difference ◽  
Sex Limitation ◽  
Heritability Estimates ◽  
Genetic And Environmental Factors

AbstractSex differences in the heritability of self-reported body-height in two Finnish twin cohorts were studied by using sex-limitation models. The first cohort was born in 1938–1949 (N = 4873 twin pairs) and the second in 1975–1979 (N = 2374 twin pairs). Body-height was greater in the younger cohort (difference of 3.1 cm for men and 2.9 cm for women). The heritability estimates were higher among men (h2 = 0.87 in the older cohort and h2 = 0.82 in the younger cohort) than women (h2 = 0.78 and h2 = 0.67, respectively). Sex-specific genetic factors were not statistically significant in either cohort, suggesting that the same genes contribute to variation in body height for both men and women. The stronger contribution of environmental factors to body-height among women questions the hypothesis that women are better buffered against environmental stress, at least for this phenotype.

Reductionist thinking and animal models in neuropsychiatric research

2019 ◽  
Vol 42 ◽  
Author(s):  
Nicole M. Baran
Keyword(s):  
Animal Models ◽  
Mental Disorders ◽  
Environmental Factors ◽  
Neuropsychiatric Disorders ◽  
Model Organisms ◽  
Developmental Genetic ◽  
Term Study ◽  
Genetic And Environmental Factors ◽  
Mechanisms Of Plasticity

AbstractReductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the “massively multifactorial system networks” which go awry in mental disorders.

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