The effect of screw design and bone mineral density on transpedicular fixation in human vertebral bodies

Computer aided image analysis was applied to elaborate an automatic method of histomorphometric analysis of trabecular bone samples. Transverse sections of decalcified vertebral bodies were examined using optical microscopy and digital image acquisition system. Further analysis was done by means of a general purpose image analysis package. The same algorithm was applied to all the images tested, thus enabling obtainment of objective and repeatable results. High efficiency in measurements and evaluation of parameters not accessible for manual methods makes this method an interesting alternative for classical histomorphometric analysis. The results obtained demonstrated that assessment of bone mineral density is not sufficient for evaluation of compression strength of vertebral bodies. In contrast, mechanical properties correlate well with histomorphometric parameters. As a consequence it was postulated that compression strength of vertebral bodies is controlled by trabecular structure rather than bone mineral density.

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A technique for measuring regional bone mineral density in human lumbar vertebral bodies

Medical Physics ◽

10.1118/1.596430 ◽

1989 ◽

Vol 16 (5) ◽

pp. 766-772 ◽

Cited By ~ 33

Author(s):

Dianna Dickie Cody ◽

Michael J. Flynn ◽

David S. Vickers

Keyword(s):

Bone Mineral Density ◽

Bone Mineral ◽

Mineral Density ◽

Regional Bone Mineral Density ◽

Vertebral Bodies

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Spine stabilization in patients with the thoracic and lumbar vertebrae fractures in reduced bone mineral density

Innovative medicine of Kuban ◽

10.35401/2500-0268-2021-23-3-31-39 ◽

2021 ◽

pp. 31-39

Author(s):

A. A. Afaunov ◽

I. V. Basankin ◽

K. K. Takhmazyan ◽

M. L. Mukhanov ◽

N. S. Chaikin

Keyword(s):

Bone Mineral Density ◽

Surgical Treatment ◽

Bone Mineral ◽

Lumbar Vertebrae ◽

Clinical Effectiveness ◽

Neurological Complications ◽

Mineral Density ◽

Transpedicular Fixation ◽

Spine Stabilization ◽

Group 2

Objective To compare the clinical effectiveness of various technical and tactical options for surgical treatment of patients with thoracic and lumbar vertebrae fractures with reduced bone mineral density.Material and Methods The study included 238 patients with the thoracic and lumbar vertebrae fractures with reduced bone mineral density (BMD). The patients were aged between 48 and 85 with T-score –1.5 to –3.5. The study did not include the patients with recurrent or multiple vertebral fractures, with absence of the clear date and fact of fracture in the case history, with neurological complications or polytrauma. The patients had fractures А1.2, А1.3, В1.2, В2.3 according to the classification of Magerl (1992). All patients underwent bisegmental transpedicular fixation (TPF). Group 1 included 68 patients who underwent non-cement augmented transpedicular screw fixation. Group 2 included 170 patients who underwent cement augmented transpedicular fixation. Both groups were divided into 2 subgroups. Subgroups 1.1 and 2.1 included patients operated in two stages. The first stage was TPF and the second stage was anterior corporodesis. Subgroups 1.2 и 2.2 included patients who underwent only TPF. Outcomes and complications were studied. The observation period lasted for not less than 2 years. Correlation analysis was performed between the technique of performing operations and surgical tactics in four subgroups and treatment outcomes.Conclusion 1. In the treatment of patients with fractures in the thoracic or lumbar spine with reduced BMD, isolated TPF with cemented screw implantation is clinically equivalent to two-stage surgical treatment - TPF with cementless or cemented implantation and anterior corprodesis of injured FPS. 2. In cementless TPF in patients with decreased BMD, anterior corprodesis of the injured VMS is necessary because its failure leads to the loss of anatomical relationship correction achieved during surgery, increase in local kyphosis, and functional maladaptation of patients.

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Bone mineral density loss post sex hormone deficiency in peripheral and central sections of rat lumbar vertebral bodies evaluated with thin slice multi-detector clinical CT

Bone ◽

10.1016/j.bone.2010.09.314 ◽

2010 ◽

Vol 47 ◽

pp. S449-S450

Author(s):

Min Deng ◽

James F. Griffith ◽

Guo-Liang Shao ◽

Yi-Xiang J. Wang

Keyword(s):

Bone Mineral Density ◽

Bone Mineral ◽

Sex Hormone ◽

Hormone Deficiency ◽

Mineral Density ◽

Bone Mineral Density Loss ◽

Thin Slice ◽

Vertebral Bodies

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MAGNETIC RESONANCE IMAGING IN THE EVALUATION OF MORPHOLOGICAL AND STRUCTURAL CHANGES OF THE VERTEBRAL BODIES OF THE LUMBAR SPINE WITH BONE MINERAL DENSITY REDUCTION

Zaporozhye Medical Journal ◽

10.14739/2310-1210.2014.1.23682 ◽

2014 ◽

Vol 0 (1) ◽

Author(s):

S. A. Myagkov ◽

A. P. Myagkov ◽

I. R. Rybak ◽

A. S. Sementsov ◽

S. Y. Nakonechniy ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Bone Mineral Density ◽

Lumbar Spine ◽

Magnetic Resonance ◽

Bone Mineral ◽

Structural Changes ◽

Resonance Imaging ◽

Mineral Density ◽

Density Reduction ◽

Vertebral Bodies

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Laterality and Plasticity of Bone Mineral Density in Vertebral Bodies of Patients with Adolescent Idiopathic Scoliosis

10.21203/rs.3.rs-337247/v1 ◽

2021 ◽

Author(s):

Takahiro Makino ◽

Shota Takenaka ◽

Yusuke Sakai ◽

Yuya Kanie ◽

TAKASHI KAITO

Keyword(s):

Bone Mineral Density ◽

Adolescent Idiopathic Scoliosis ◽

Idiopathic Scoliosis ◽

Bone Mineral ◽

Vertebral Body ◽

Quantitative Computed Tomography ◽

External Loading ◽

Mineral Density ◽

Asymmetrical Distribution ◽

Vertebral Bodies

Abstract BackgroundThe asymmetrical distribution of bone mineral density (BMD) in vertebral bodies in adolescent idiopathic scoliosis (AIS) has been reported; however, it is still unknown whether BMD asymmetrical distribution can vary by the mechanical environment around each vertebral body. The purpose of this retrospective study was to investigate changes in the asymmetrical distribution of BMD in each vertebral body up to 1 year after posterior spinal corrective fusion surgery (PSF) in patients with AIS.MethodsWe analyzed 75 vertebrae within the non-instrumented lumbar spines of 27 female AIS patients (median age, 16 years; interquartile range [IQR], 14–19 years) who underwent PSF. The BMDs of the vertebral bodies were calculated from 1-week and 1-year postoperative quantitative computed tomography scans and a laterality index (LI = BMD of right half of vertebral bodies / BMD of left half of vertebral bodies). The disc wedging angle was measured preoperatively and at 1 year postoperatively from plain radiographs, and the disc wedging angle index (DWAI) was calculated as the sum of the disc wedging angles of the upper and lower discs adjacent to each vertebra.ResultsThe median BMDs of both the right and left halves of each vertebral body significantly decreased from 1 week postoperatively to 1 year postoperatively (right, 228.3 mg/cm3 hydroxyapatite [IQR, 201.8–251.0 mg/cm3 hydroxyapatite] to 214.8 mg/cm3 hydroxyapatite [IQR, 186.9–241.0 mg/cm3 hydroxyapatite], P < 0.001; left, 229.6 mg/cm3 hydroxyapatite [IQR, 198.7–244.7 mg/cm3 hydroxyapatite] to 206.3 mg/cm3 hydroxyapatite [IQR, 188.0–231.9 mg/cm3 hydroxyapatite], P < 0.001). The preoperative median DWAI was 5.0 (IQR, −12.0–13.0) and the 1-week postoperative LI was 1.01 (IQR, 0.95–1.08); these measures were positively correlated (ρ = 0.827; P < 0.001). The median perioperative change in DWAI was −4 (IQR, −9–10) and the median postoperative change in LI was 0.01 (IQR, −0.02–0.03); these measures were also positively correlated (ρ = 0.741; P < 0.001).ConclusionsThe laterality of BMD in each vertebral body in AIS patients was a plastic phenomenon, was deemed a secondary change due to external loading, and was related to the amount of disc wedging.

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