Acute scrotum caused by Henoch-Schönlein purpura, with immediate response to short-term steroid therapy

1995 ◽  
Vol 30 (10) ◽  
pp. 1509-1510 ◽  
Author(s):  
Jacob Ben-Chaim ◽  
Endu Korat ◽  
Ofer Shenfeld ◽  
Ariyeh Shelhav ◽  
Paul Jonas ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Acute Scrotum ◽  
Henoch Schonlein Purpura ◽  
Short Term ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Immediate Response

A rapid response to steroid therapy in acute scrotum: A case of Henoch-Schönlein purpura

2012 ◽  
pp. 71-74
Author(s):  
Ali Kanık ◽  
Engin Köse ◽  
Kayı Eliaçık ◽  
Seda Şirin Köse ◽  
Nil Cefa Arslan ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Rapid Response ◽  
Acute Scrotum ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Acute haemorrhagic oedema of infancy: a condition that is not always benign

2020 ◽  
Vol 13 (11) ◽  
pp. e236059
Author(s):  
Ugo Cucinotta ◽  
Francesca Mazza ◽  
Giovanni Battista Pajno ◽  
Romina Gallizzi
Keyword(s):  
Clinical Outcome ◽  
Steroid Therapy ◽  
Rare Condition ◽  
Henoch Schonlein Purpura ◽  
Benign Condition ◽  
Atypical Case ◽  
Systemic Involvement ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Acute haemorrhagic oedema of infancy (AHOI) is a rare condition and an unusual diagnosis for the paediatrician, as approximately 300 cases have been reported in literature so far. Although it was considered for years a less serious variant of Henoch-Schönlein purpura, nowadays it is thought to be a different entity, with his own characteristics and clinical outcome. In literature it is described as a benign condition, self-limiting and without any systemic involvement in most of the cases. We present an atypical case of AHOI with a severe presentation and which needed an aggressive and prolonged steroid therapy.

scholarly journals Treatment of Complicated Henoch-Schönlein Purpura with Mycophenolate Mofetil: A Retrospective Case Series Report

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
A. A. Nikibakhsh ◽  
H. Mahmoodzadeh ◽  
M. Karamyyar ◽  
S. Hejazi ◽  
M. Noroozi ◽  
...  
Keyword(s):  
Mycophenolate Mofetil ◽  
Steroid Therapy ◽  
Central Nervous System Involvement ◽  
Case Series ◽  
Systemic Steroid ◽  
Henoch Schonlein Purpura ◽  
Retrospective Case ◽  
Frequent Relapses ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Background. Henoch-Schönlein purpura (HSP) is the most common childhood vasculitis with an incidence of approximately 10 per 100 000 children. There is some evidence to support steroid therapy in the treatment of severe abdominal pain, severe nephritis, and central nervous system involvement. However, the routine use of corticosteroids is controversial. Frequent relapses, lack of response to steroid, steroid dependency, and steroid side effects may occur in some patients. Mycophenolate mofetil (MMF) gains increasing popularity in the treatment of autoimmune disorders, but hitherto, the available evidence to support the use of MMF in HSP is limited to some case study reports.Case Presentation. We report six children with HSP who failed to respond to systemic steroid therapy, whereas MMF successfully treated the manifestations of the disease.Conclusion. The manifestations of HSP disappeared mainly during the first week of treatment with MMF and all the patients were in a complete remission at the end and after discontinuation of the therapy. In our experience, MMF appeared to be safe and effective for the maintenance of remission in the HSP patients.

Interessamento genitale della porpora di Schönlein-Henoch

2021 ◽  
Vol 24 (3) ◽  
pp. 73-74
Author(s):  
Nicola Tovaglieri ◽  
Rossella Amariti ◽  
Francesca Loiacono ◽  
Costantino De Giacomo
Keyword(s):  
Clinical Response ◽  
Steroid Therapy ◽  
Lower Limbs ◽  
Oral Steroid ◽  
Posterior Surface ◽  
Henoch Schonlein Purpura ◽  
Kidney Involvement ◽  
Oral Steroid Therapy ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schönlein purpura (HSP) is a paediatric vasculitis, affecting several organs. Purpura is typically found on posterior surface of lower limbs and is more often associated with joint, abdominal and kidney involvement. The paper reports a case of HSP with mild cutaneous and abdominal manifestations, with genital involvement (haemorrhagic oedema of the penis that is more rarely described in literature), which was treated with oral steroid therapy that led to an optimal clinical response.

scholarly journals Efficacy of Triptolide for Children with Moderately Severe Henoch-Schönlein Purpura Nephritis Presenting with Nephrotic Range Proteinuria: A Prospective and Controlled Study in China

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Li Wu ◽  
Jianhua Mao ◽  
Xia Jin ◽  
Haidong Fu ◽  
Huijun Shen ◽  
...  
Keyword(s):  
Treatment Group ◽  
Control Group ◽  
Henoch Schonlein Purpura ◽  
Short Term ◽  
Significant Difference ◽  
Schonlein Purpura ◽  
Nephrotic Range Proteinuria ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

Objective.To observe the clinical efficacy of the Chinese herb, Triptolide, in children with moderately severe Henoch-Schönlein purpura nephritis (HSPN).Methods. From January 2007 to December 2011, 56 HSPN children manifested by nephrotic range proteinuria with normal kidney function and<50% crescents or sclerosing lesions on biopsy were hospitalized in the Children’s Hospital of Zhejiang University School of Medicine. They were divided into two groups: the treatment group (Triptolide at a dosage of 1 mg/kg·d, combined with prednisone at a dosage of 2 mg/kg·d, within a course of medium-to-long-term therapy of 6 to 9 months) and the control group (; prednisone alone, with the same procedure).Results.Short-term remission was observed in 95% of patients from treatment group and in 72% of patients from control group, respectively. There was a significant difference between both groups () for short-term effects. Meanwhile, no significant difference, as proteinuria, hematuria, hypertension, and decreased eGFR, was observed between the two groups in long-term followup (). The Kaplan-Meier plot analysis also revealed no significant difference ().Conclusion.Triptolide is effective in relieving short-term symptoms for moderately severe HSPN children, though its long-term effects need to be observed further.

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