Acceleration of functional recovery following lateral hypothalamic damage by means of electrical stimulation in the lesioned areas

1974 ◽  
Vol 12 (5) ◽  
pp. 897-899 ◽  
Author(s):  
L.E. Harrell ◽  
R. Raubeson ◽  
S. Balagura
Keyword(s):  
Electrical Stimulation ◽  
Functional Recovery ◽  
Lateral Hypothalamic ◽  
Hypothalamic Damage

Sensory Neglect Produced by Lateral Hypothalamic Damage

Science ◽  
1971 ◽  
Vol 174 (4008) ◽  
pp. 523-525 ◽  
Author(s):  
J. F. Marshall ◽  
B. H. Turner ◽  
P. Teitelbaum
Keyword(s):  
Lateral Hypothalamic ◽  
Sensory Neglect ◽  
Hypothalamic Damage

scholarly journals Subthreshold electrical stimulation as a low power electrical treatment for stroke rehabilitation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyungsoo Kim ◽  
Seung-Jun Yoo ◽  
So Yeon Kim ◽  
Taeju Lee ◽  
Sung-Ho Lim ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Energy Consumption ◽  
Functional Recovery ◽  
Stroke Rehabilitation ◽  
Brain Regions ◽  
Implantable Devices ◽  
Rehabilitation Process ◽  
Neural Excitability ◽  
Spike Firing

AbstractAs a promising future treatment for stroke rehabilitation, researchers have developed direct brain stimulation to manipulate the neural excitability. However, there has been less interest in energy consumption and unexpected side effect caused by electrical stimulation to bring functional recovery for stroke rehabilitation. In this study, we propose an engineering approach with subthreshold electrical stimulation (STES) to bring functional recovery. Here, we show a low level of electrical stimulation boosted causal excitation in connected neurons and strengthened the synaptic weight in a simulation study. We found that STES with motor training enhanced functional recovery after stroke in vivo. STES was shown to induce neural reconstruction, indicated by higher neurite expression in the stimulated regions and correlated changes in behavioral performance and neural spike firing pattern during the rehabilitation process. This will reduce the energy consumption of implantable devices and the side effects caused by stimulating unwanted brain regions.

Subthreshold Electrical Stimulation as A Low Power Electrical Treatment for Stroke Rehabilitation

2021 ◽  
Author(s):  
Kyungsoo Kim ◽  
Seung-Jun Yoo ◽  
So Yeun Kim ◽  
Taeju Lee ◽  
Sung-Ho Lim ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Energy Consumption ◽  
Functional Recovery ◽  
Stroke Rehabilitation ◽  
Brain Regions ◽  
Implantable Devices ◽  
Rehabilitation Process ◽  
Neural Excitability ◽  
Spike Firing

Abstract As a promising future treatment for stroke rehabilitation, researchers have developed direct brain stimulation to manipulate the neural excitability. However, there has been less interest in energy consumption and unexpected side effect caused by electrical stimulation to bring functional recovery for stroke rehabilitation. In this study, we propose an engineering approach with subthreshold electrical stimulation (STES) to bring functional recovery. Here, we show a low level of electrical stimulation boosted causal excitation in connected neurons and strengthened the synaptic weight in a simulation study. We found that STES with motor training enhanced functional recovery after stroke in vivo. STES was shown to induce neural reconstruction, indicated by higher neurite expression in the stimulated regions and correlated changes in behavioral performance and neural spike firing pattern during the rehabilitation process. This will reduce the energy consumption of implantable devices and the side effects caused by stimulating unwanted brain regions.

Accelerating functional recovery after rat facial nerve injury: Effects of gonadal steroids and electrical stimulation

2008 ◽  
Vol 139 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Laura E. T. Hetzler ◽  
Nijee Sharma ◽  
Lisa Tanzer ◽  
Robert D. Wurster ◽  
John Leonetti ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Facial Nerve ◽  
Nerve Injury ◽  
Functional Recovery ◽  
Gonadal Steroids ◽  
Facial Nerve Injury

Avoidance and approach learning motivated by stimulation of identical hypothalamic loci

1959 ◽  
Vol 197 (1) ◽  
pp. 153-157 ◽  
Author(s):  
George W. Brown ◽  
Bertram D. Cohen
Keyword(s):  
Electrical Stimulation ◽  
Lateral Hypothalamus ◽  
Opportunity To Learn ◽  
Hypothalamic Stimulation ◽  
Experimental Conditions ◽  
Approach Response ◽  
Lateral Hypothalamic ◽  
Stimulating Electrodes ◽  
Second Procedure ◽  
Stimulation Of

Cats with stimulating electrodes implanted in the lateral hypothalamus were subjected to two types of experimental procedures. In the first procedure the cats were given an opportunity to learn to avoid hypothalamic stimulation which produces a typical ‘hypothalamic rage’ response. The second procedure allows the same cats to learn to approach an area where the hypothalamic stimulus is administered. In both procedures, electrical stimulation was delivered through identical electrodes, yet each animal learned the appropriate avoidance or approach response, depending upon the experimental conditions. Therefore, lateral hypothalamic stimulation may act as an energizing, drive-arousing, operation to produce both avoidance and approach learning in cats.

Sign in / Sign up

Export Citation Format

Share Document