Appearance of virus-specific RNA, virus particles, and cell surface changes in cells rapidly transformed by the murine sarcoma virus

Virology ◽  
1973 ◽  
Vol 53 (1) ◽  
pp. 186-195 ◽  
Author(s):  
Samuel Salzberg ◽  
Martin S. Robin ◽  
Maurice Green
Keyword(s):  
Cell Surface ◽  
Rna Virus ◽  
Virus Particles ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Cell Surface Changes ◽  
Murine Sarcoma ◽  
Surface Changes ◽  
In Cells

Studies on Murine Sarcoma Virus III. Synthesis of the Viral Antigens in Cells of Various Species

1972 ◽  
Vol 139 (3) ◽  
pp. 1071-1077 ◽  
Author(s):  
J. C. Chuat ◽  
C. Bernard ◽  
F. Lasquellec ◽  
P. Tchen ◽  
M. Boiron
Keyword(s):  
Viral Antigens ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Murine Sarcoma ◽  
In Cells

A Report Of Morphologically Aberrant Virus Particles in Cells Infected With MSV (FelLV) Virus

1973 ◽  
Vol 31 ◽  
pp. 584-585
Author(s):  
R. A. Al-Adhami ◽  
A. L. Chapman
Keyword(s):  
Leukemia Virus ◽  
Feline Leukemia Virus ◽  
Virus Particles ◽  
Induced Tumors ◽  
Embryo Cells ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Mouse Cells ◽  
Type C ◽  
Murine Sarcoma

Fujinaga et al reported MSV induced rat and hamster osteosarcoma which showed an occassional unusual bud in the rat induced tumors. Savage and Hackett and Hackett and Sylvester reported abnormal type C virus in UCLB cells derived from Balb/3t3 cells infected and transformed with MLV. They wer unable to demonstrate sarcoma virus activity. Fischinger and O‘Connor reported the infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus designated as MSV(FelLV). This virus gave rise to a defective, focus forming virus which propagated in cat cells but not in mouse cells.In the present study the morphoiogy of the MSV(FelLV) virus obtained from Dr. Fischinger and maintained in our laboratory since 1970 will be reported. Feline embryo fibroblasts (established in our lab.) and Crandall feline kidney cells (Cutter-Haver-Lockhart, Shawnee, Kansas) were used in this study.

scholarly journals Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene.

1983 ◽  
Vol 3 (12) ◽  
pp. 2298-2301 ◽  
Author(s):  
L F Parada ◽  
R A Weinberg
Keyword(s):  
Human Tumor ◽  
Mouse Fibroblast ◽  
Ras Oncogene ◽  
Ras Gene ◽  
In Vitro Exposure ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Murine Sarcoma ◽  
In Cells

Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro exposure to the carcinogen 3-methylcholanthrene. These oncogenes are now shown to be versions of the cellular Kirsten ras gene and are therefore homologous to oncogenes detected in a variety of human tumor DNAs.

Sign in / Sign up

Export Citation Format

Share Document