[56] Use of lipid bilayer membranes to detect pore formation by toxins

1994 ◽  
pp. 691-705 ◽  
Author(s):  
Bruce L. Kagan ◽  
Yuri Sokolov
Keyword(s):  
Lipid Bilayer ◽  
Pore Formation ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes

Formation and stabilization of pores in bilayer membranes by peptide-like amphiphilic polymers

Soft Matter ◽  
2018 ◽  
Vol 14 (13) ◽  
pp. 2526-2534 ◽  
Author(s):  
Ankush Checkervarty ◽  
Marco Werner ◽  
Jens-Uwe Sommer
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Lipid Bilayer ◽  
Pore Formation ◽  
Amphiphilic Polymers ◽  
Amphiphilic Copolymers ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Fluid Membrane ◽  
Brush Model

We study pore formation in models of lipid bilayer membranes interacting with amphiphilic copolymers mimicking anti-microbial peptides using Monte Carlo simulations and we rationalize our results by a simple brush-model for the fluid membrane.

scholarly journals Pore formation by LamB of Escherichia coli in lipid bilayer membranes.

1986 ◽  
Vol 165 (3) ◽  
pp. 978-986 ◽  
Author(s):  
R Benz ◽  
A Schmid ◽  
T Nakae ◽  
G H Vos-Scheperkeuter
Keyword(s):  
Escherichia Coli ◽  
Lipid Bilayer ◽  
Pore Formation ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes

scholarly journals Pores formed in lipid bilayer membranes by nystatin, Differences in its one-sided and two-sided action.

1975 ◽  
Vol 65 (4) ◽  
pp. 515-526 ◽  
Author(s):  
A Marty ◽  
A Finkelstein
Keyword(s):  
Hydrogen Bonding ◽  
Lipid Bilayer ◽  
Pore Formation ◽  
Plasma Membranes ◽  
Bilayer Membrane ◽  
Bilayer Structure ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
The One

Nystatin and amphotericin B induce a cation-selective conductance when added to one side of a lipid bilayer membrane and an anion-selective conductance when added to both sides. The concentrations of antibiotic required for the one-sided action are comparable to those employed on plasma membranes and are considerably larger than those required for the two-sided action. We propose that the two-sided effect results from the formation of aqueous pores formed by the hydrogen bonding in the middle of the bilayer of two "half pores," whereas the one-sided effect results from the half pores alone. We discuss, in terms of the flexibility of bilayer structure and its thickness, how it is possible to have conducting half pores and "complete pores" in the same membrane. The role of sterol (cholesterol and ergosterol) in pore formation is also examined.

scholarly journals Macromolecular Crowding Affects Voltage-Dependent Alamethicin Pore Formation in Lipid Bilayer Membranes

2020 ◽  
Vol 124 (25) ◽  
pp. 5095-5102
Author(s):  
William T. McClintic ◽  
Graham J. Taylor ◽  
Michael L. Simpson ◽  
C. Patrick Collier
Keyword(s):  
Lipid Bilayer ◽  
Pore Formation ◽  
Macromolecular Crowding ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Voltage Dependent
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