Classification of hepatitis C virus into major types and subtypes based on molecular evolutionary analysis

1995 ◽  
Vol 36 (2-3) ◽  
pp. 201-214 ◽  
Author(s):  
Ken-ichi Ohba ◽  
Masashi Mizokami ◽  
Tomoyoshi Ohno ◽  
Kaoru Suzuki ◽  
Etsuro Orito ◽  
...  
2014 ◽  
Vol 548-549 ◽  
pp. 1265-1269
Author(s):  
Yun Sik Hwang ◽  
Byeong Joo Jun ◽  
Tae Seon Yoon

As the stage of bioinformatics has been upgraded, classification of certain pathogen has been improved into a new manner. The main topic of this research is genetic singularity of HCV (Hepatitis C Virus) and our objective is to assay features of the HCV's amino acid under usage of Support Vector Machine (SVM) algorithm. HCV data used in our experiment has 10 kinds of sequences and 257 kinds of data. According to data analysis, some peculiar genetic patterns of HCV’s linearity that discord pre-existing neural network and C5.0 were found.


2007 ◽  
Vol 88 (5) ◽  
pp. 1519-1525 ◽  
Author(s):  
Ling Lu ◽  
Chunhua Li ◽  
Yongshui Fu ◽  
Fengxiang Gao ◽  
Oliver G. Pybus ◽  
...  

Five hepatitis C virus (HCV) complete genome sequences (Th846, 537796, QC227, QC216 and QC99) from a blood donor in Thailand and three Asian immigrants and one Caucasian in North America were determined. Phylogenetically, they represent the first complete genomes for subtypes 6c, 6l, 6o, 6p and 6q, respectively. Similarity analysis showed no evidence of inter- or intrasubtype recombination. Further analysis in conjunction with partial sequences from the Los Alamos HCV database led to the identification of other closely related isolates from south-eastern Asia or immigrants from that region. However, Th846 did not cluster with any reference sequence and is the sole isolate of subtype 6c reported so far. This study completes the full genome sequencing of all 17 assigned HCV genotype 6 subtypes (6a–6q). The utility of this panel of complete sequences for accurate detection and classification of infection, and for estimating the origin of this genotype of HCV, is discussed.


Hepatology ◽  
2013 ◽  
Vol 59 (1) ◽  
pp. 318-327 ◽  
Author(s):  
Donald B. Smith ◽  
Jens Bukh ◽  
Carla Kuiken ◽  
A. Scott Muerhoff ◽  
Charles M. Rice ◽  
...  

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