Different amounts of cytochrome P-450 dependent monooxygenases in tulip bulbs, pea seedlings and maize endosperm cells

Plant Science ◽  
1994 ◽  
Vol 99 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Laura Marabini ◽  
Sonia Radice ◽  
Barbara Cipelletti ◽  
Enzo Chiesara
1985 ◽  
Vol 49 (8) ◽  
pp. 2399-2405 ◽  
Author(s):  
Ken HIGASHI ◽  
Kie IKEUCHI ◽  
Masanobu OBARA ◽  
Yuji KARASAKI ◽  
Hideyasu HIRANO ◽  
...  

1982 ◽  
Vol 70 (1) ◽  
pp. 122-126 ◽  
Author(s):  
Irène Benveniste ◽  
Jean-Pierre Salaün ◽  
Annick Simon ◽  
Danièle Reichhart ◽  
Francis Durst

1985 ◽  
Vol 49 (8) ◽  
pp. 2399-2405 ◽  
Author(s):  
Ken Higashi ◽  
Kie Ikeuchi ◽  
Masanobu Obara ◽  
Yuji Karasaki ◽  
Hideyasu Hirano ◽  
...  

1996 ◽  
Vol 61 (11) ◽  
pp. 1689-1696
Author(s):  
Marie Stiborová ◽  
Hana Hansíková

The microsomal fraction from tulip bulbs (Tulipa fosteriana L.) contains cytochrome P-450 enzymes catalyzing the NADPH-dependent oxidation of the xenobiotic substrate, an azo dye Sudan I (1-phenylazo-2-hydroxynaphthalene, Solvent Yellow 14). C-Hydroxy derivatives [1-(4-hydroxyphenylazo)-2-hydroxynaphthalene, 1-phenylazo-2,6-dihydroxynaphthalene, 1-(4-hydroxyphenylazo)-2,6-dihydroxynaphthalene] and the benzenediazonium ion are the products of the Sudan I oxidation. The oxidation of Sudan I has also been assessed in a reconstituted electron-transport chain with the isolated cytochrome P-450, isolated plant NADPH-cytochrome P-450 reductase and phospholipid. The results are discussed from the point of view of the role of cytochromes P-450 in the metabolism of xenobiotics in plants.


1983 ◽  
Vol 115 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Ken Higashi ◽  
Kie Ikeuchi ◽  
Yuji Karasaki ◽  
Masanobu Obara

Author(s):  
W. Kuenzig ◽  
M. Boublik ◽  
J.J. Kamm ◽  
J.J. Burns

Unlike a variety of other animal species, such as the rabbit, mouse or rat, the guinea pig has a relatively long gestation period and is a more fully developed animal at birth. Kuenzig et al. reported that drug metabolic activity which increases very slowly during fetal life, increases rapidly after birth. Hepatocytes of a 3-day old neonate metabolize drugs and reduce cytochrome P-450 at a rate comparable to that observed in the adult animal. Moreover the administration of drugs like phenobarbital to pregnant guinea pigs increases the microsomal mixed function oxidase activity already in the fetus.Drug metabolic activity is, generally, localized within the smooth endoplasmic reticulum (SER) of the hepatocyte.


1994 ◽  
Vol 92 (4) ◽  
pp. 661-667 ◽  
Author(s):  
Mariken Rebers ◽  
Gaea Romeijn ◽  
Erik Knegt ◽  
Linus H. W. van der Plas
Keyword(s):  

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