Effects of LCT-infusion in skeletal muscle in the postoperative state - long chain fatty acids in VLDL-triglycerides and free fatty acids

1985 ◽  
Vol 4 ◽  
pp. 110
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Free Fatty Acids ◽  
Long Chain Fatty Acids ◽  
Postoperative State ◽  
Long Chain ◽  
Chain Fatty Acids

scholarly journals Selective transport of long-chain fatty acids by FAT/CD36 in skeletal muscle of broilers

animal ◽  
2013 ◽  
Vol 7 (3) ◽  
pp. 422-429 ◽  
Author(s):  
J. Guo ◽  
G. Shu ◽  
L. Zhou ◽  
X. Zhu ◽  
W. Liao ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Long Chain Fatty Acids ◽  
Selective Transport ◽  
Long Chain ◽  
Chain Fatty Acids

Metabolism of free fatty acids by myocardium and kidney

1964 ◽  
Vol 206 (1) ◽  
pp. 153-158 ◽  
Author(s):  
Martin Gold ◽  
John J. Spitzer
Keyword(s):  
Fatty Acids ◽  
Palmitic Acid ◽  
Free Fatty Acids ◽  
Coronary Sinus ◽  
Renal Vein ◽  
Specific Activity ◽  
Long Chain Fatty Acids ◽  
Significant Production ◽  
Long Chain ◽  
Chain Fatty Acids

The myocardial and renal removal and oxidation of plasma free fatty acids (FFA) were studied in dogs receiving an infusion of I-C14-palmitate, oleate, linoleate, or octanoate. The myocardium extracted about 40% of the total arterial FFA, and some was oxidized to CO2. Blood C14O2 was consistently higher in the coronary sinus than in the artery. The specific activity of the coronary sinus C14O2 was higher than that of the arterial C14O2 in dogs infused with long-chain fatty acids. The specific activity of arterial C14O2 was higher than that of the coronary sinus C14O2 when octanoate was infused. There were no differences observed in FFA extraction and C14O2 production among the different groups of animals receiving the various long-chain fatty acids. In gas chromatographic studies palmitic acid was the only FFA with a consistent net removal by the kidney. Approximately 9% of the arterial radiopalmitate was removed by this organ in dogs receiving infusions of palmitic acid-1-C14. Simultaneously, C14O2 was produced by the kidney. A consistent removal of oleate-1-C14 or a significant production of C14O2 was not found. Infusion of octanoate-1-C14 led to a marked release of C14O2 by the kidney, with greatly increased CO2 specific activity in the renal vein.

scholarly journals The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4

Diabetes ◽  
2020 ◽  
Vol 69 (11) ◽  
pp. 2281-2293 ◽  
Author(s):  
Tim Benninghoff ◽  
Lena Espelage ◽  
Samaneh Eickelschulte ◽  
Isabel Zeinert ◽  
Isabelle Sinowenka ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Long Chain Fatty Acids ◽  
Fatty Acid Transporter ◽  
Acid Transporter ◽  
Long Chain ◽  
Chain Fatty Acids

scholarly journals Increased Accumulation of Long‐chain Fatty Acids in Skeletal Muscle May Contribute Insulin Resistance in Znt7 Knockout Mice

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Surapun Tepaamorndech ◽  
Catherine Kirschke ◽  
Theresa Pedersen ◽  
William Keyes ◽  
John Newman ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Fatty Acids ◽  
Knockout Mice ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

Free fatty acid metabolism by skeletal muscle

1964 ◽  
Vol 206 (1) ◽  
pp. 159-164 ◽  
Author(s):  
John J. Spitzer ◽  
Martin Gold
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Specific Activity ◽  
Venous Blood ◽  
Long Chain Fatty Acids ◽  
Carbon 14 ◽  
Arterial Blood ◽  
Free Fatty Acid Metabolism ◽  
Long Chain ◽  
Chain Fatty Acids

Removal and oxidation of free fatty acids (FFA) were studied by the electrically stimulated skeletal muscle in dogs receiving an infusion of I-C14-palmitate, oleate, linoleate, or octanoate. Resting skeletal muscle removed about 43% of the arterial FFA. The A-V difference was directly proportional to the arterial FFA level. During electrical stimulation the removal increased due to the increased blood flow while the extraction ratio decreased. A portion of the infused carbon 14 appeared in the venous blood as C14O2 in all animals receiving either long-chain fatty acids or octanoate. The specific activity of C14O2 in the venous blood became higher than that in the arterial blood during stimulation when long-chain fatty acids were infused, but did not undergo such changes when octanoate was infused. No differences were observed between the different groups of animals receiving the various long-chain fatty acids. It is postulated that only a fraction of the removed FFA is immediately oxidized, while a portion is stored and oxidized at a later date.

scholarly journals Transcriptional regulation of skeletal muscle GLUT4 by elevated long chain fatty acids

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Terry E. Jones ◽  
L. Brittany Rice ◽  
Jonathan E. Williams ◽  
Morgan M. Pearce
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acids ◽  
Transcriptional Regulation ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids
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