Portal haemodynamics of oesophageal varices bleeding and portal hypertensive gastropathy in liver cirrhosis

Hepatology ◽  
1994 ◽  
Vol 19 (4) ◽  
pp. I126
Author(s):  
N Soemarno
Keyword(s):  
Liver Cirrhosis ◽  
Oesophageal Varices ◽  
Portal Hypertensive Gastropathy

scholarly journals Peptic Ulcer Diseases in Patients with Liver Cirrhosis and Portal Hypertension: Experience in a Tertiary Level Hospital in Bangladesh

2021 ◽  
Vol 16 (2) ◽  
pp. 68-71
Author(s):  
Ahmed Lutful Moben ◽  
Md Abdullahel Kafee ◽  
Md Jahangir Kabir ◽  
Arunanagshu Raha ◽  
Farjana Majid ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Peptic Ulcer ◽  
Portal Hypertension ◽  
Peptic Ulcer Disease ◽  
Oesophageal Varices ◽  
Portal Hypertensive Gastropathy ◽  
Class Iii ◽  
Cross Sectional ◽  
Ulcer Disease ◽  
Cirrhosis Of Liver

Introduction: Cirrhosis of liver and peptic ulcer disease (PUD) are very common in Bangladesh. PUD may coexist with cirrhosis and portal hypertension. Haematemesis and melaena in cirrhosis of liver are not always from ruptured oesophageal varices; rather it may be due to bleeding peptic ulcer disease. Objective: To find the prevalence of PUD among patients with liver cirrhosis and portal hypertension. Materials and Methods: This cross sectional, descriptive study was conducted on 96 patients of cirrhosis of liver diagnosed with oesophageal varices at endoscopy unit of Kurmitola general hospital, during endoscopic evaluations in 4 months period from september 2017 to december 2017. Results: Total cirrhotic patients enrolled were 96 (M=61, F=35), mean age was 51.8 ± 14.2 yrs (18-86years). Hepatitis B virus (HBV) was the leading cause of cirrhosis in 54.1%, Hepatitis C virus (HCV) 5.2 %, proven non-alcoholic steatohepatitis (NASH) were 11.5% and rest were from unknown aetiology. Their average Child-Turcotte-Pugh (CTP) score were 8.6 (12-5), 37.6% associated with portal hypertensive gastropathy. Grade-III oesophageal varices found in 52 patients, whereas grade-II in 25 patients. Among this 96 patients 39 (40.6%) revealed peptic ulcer disease more in the form of gastric ulcer (n=23) than duodenal ulcer (n=10) and both (n=6). Most of the ulcers belonged to Forrest class III (76.9%). Conclusions: Variceal bleeding and portal hypertensive gastropathy are the common causes of bleeding and anaemia in patients with cirrhosis of liver. Peptic ulcer disease has been found to be one of the potential causes of haematemesis, melaena, and anaemia among these patients in Bangladesh. Large multicenter controlled studies are needed to confirm the reports. JAFMC Bangladesh. Vol 16, No 2 (December) 2020: 68-71

scholarly journals Oesophageal varices, portal hypertensive gastropathy and spontaneous Sub-arachnoid haemorrhage in a case of liver cirrhosis diagnosed on autopsy.

2021 ◽  
Vol 9 (3) ◽  
Author(s):  
Luv Sharma ◽  
Pardeep Yadav ◽  
Mahender Singh
Keyword(s):  
Liver Cirrhosis ◽  
Risk Factor ◽  
Esophageal Varices ◽  
Chronic Alcoholism ◽  
Oesophageal Varices ◽  
Portal Hypertensive Gastropathy ◽  
Chronic Alcoholic ◽  
Male Individual ◽  
Autopsy Examination ◽  
Arachnoid Hemorrhage

Alcohol remains one of the most abused substances worldwide. Studies over the years have attributed chronic alcoholism as a major risk factor to liver cirrhosis. Patients with liver cirrhosis develop portal hypertension which put them at a higher risk of having esophageal varices and other associated complications. The authors present a case of a chronic alcoholic male individual who developed cirrhosis along with other less reported complications like sub-arachnoid hemorrhage and portal hypertensive gastropathy. The paper also profiles various changes associated with esophageal varices as observed during autopsy examination.

scholarly journals Noninvasive assessment of oesophageal varices presence and size in patients with liver cirrhosis using right liver lobe/serum albumin concentration

2007 ◽  
Vol 64 (7) ◽  
pp. 453-457
Author(s):  
Tamara Alempijevic ◽  
Vladislava Bulat ◽  
Nada Kovacevic ◽  
Rada Jesic ◽  
Srdjan Djuranovic ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Oesophageal Varices ◽  
Digestive Endoscopy ◽  
Liver Lobe ◽  
Albumin Ratio ◽  
Cirrhotic Patients ◽  
The Mean ◽  
Upper Digestive Endoscopy ◽  
The Right

Background/Aim. Liver cirrhosis is a chronic, progressive disease and it is usually accompanied by portal hypertension. The development of oesophageal varices (OV) is one of the major complications of portal hypertension. Cirrhotic patients should be screened for the presence of OV when portal hypertension is diagnosed. In order to reduce the increasing burden that endoscopy units have to bear, some studies have attempted to identify parameters for noninvasive prediction of OV presence. The aim of our study was to evaluate the value of biochemical and ultrasonography parameters for prediction of OV presence. Methods. This study included 58 cirrhotic patients who underwent a complete biochemical workup, ultrasonography examination and upper digestive endoscopy. Right liver lobe diameter/albumin ratio was calculated and its correlation to the presence and degree of OV, and Child-Pugh score of liver cirrhosis explored. Results. The mean age of the patients included in the study was 53.07?13.09 years; 40 were males and 18 females. In the Child-Pugh class A were 53.4% patients, class B 39.7%, whereas 6.9% were in the class C. In 24.1% of the patients no OV were identified by upper digestive endoscopy, 19% had OV grade I, 34.5% grade II, 20.7% grade III, and 1.7% OV grade IV. The mean value of the right liver lobe diameter/ albumin ratio was 5.43?1.79 (range of 2.76?11.44). Statistically significant correlation (p < 0.01) was confirm by Spearman's test between OV grade and calculated index (? = 0.441). Conclusion. The right liver lobe diameter/albumin ratio is a noninvasive parameter which provides an accurate information pertinent to the determination of OV presence and their grading in patients with liver cirrhosis. .

Correlation Between Splenomegaly and Oesophageal Varices in Patients with Liver Cirrhosis

Endoscopy ◽  
1994 ◽  
Vol 26 (06) ◽  
pp. 563-563 ◽  
Author(s):  
D. N. Amarapurkar ◽  
S. S. Parikh ◽  
K. Shankaran ◽  
K. Chopra ◽  
P. Dhawan ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Oesophageal Varices

What is the clinical relevance of portal hypertensive gastropathy (PHG) in patients with compensated liver cirrhosis?

2001 ◽  
Vol 33 ◽  
pp. A61
Author(s):  
Filippo Schepis ◽  
Calogero Cammá ◽  
Roberto De Franchis ◽  
Domenico Niceforo ◽  
Antonio Magnano ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Clinical Relevance ◽  
Portal Hypertensive Gastropathy

scholarly journals Platelet Count/Splenic Diameter Ratio to Predict Oesophageal Varices in Portal Hypertension

2019 ◽  
Vol 2 (2) ◽  
pp. 192-196
Author(s):  
Buddhi Sagar Lamichhane ◽  
Manoj Koirala ◽  
Bishwo Raj Baral
Keyword(s):  
Liver Cirrhosis ◽  
Platelet Count ◽  
Portal Hypertension ◽  
Esophageal Varices ◽  
Rural Areas ◽  
Predictive Value ◽  
Tertiary Hospital ◽  
Diameter Ratio ◽  
Oesophageal Varices ◽  
Cirrhosis Of Liver

Background: One of the major causes of morbidity and mortality in Nepal is portal hypertension due to liver cirrhosis. In rural areas where a lot of cases of cirrhosis of liver are prevalent and endoscopic expertise and facilities are not available, predicting the presence of esophageal varices through non-invasive means may reduce a large number of unnecessary endoscopies. This study is to identify the relationship of platelet count /splenic bipolar diameter ratio with the presence of esophageal varices in portal hypertension. Materials and methods: Eighty patients were included in this study between Jestha 2072 to Baisakh 2073 with the diagnosis of portal hypertension admitted in Bir hospital, Kathmandu which is a tertiary hospital of government of Nepal, which were mostly due to liver cirrhosis. The patients fulfilling the inclusion criteria underwent lab investigations, ultra sonogram and UGI endoscopy. The data were assessed for descriptive studies and means were compared using t-test. The cut off value of platelet count to spleen diameter ratio of 1150 was used to predict the presence or absence of oesophageal varices. Statistical analysis was done using SPSS 20 software Results: Platelet count to splenic diameter ratio with a cut off value of 1150 has sensitivity of 89.7%, specificity of 83.3%, positive predictive value of 96.8% and negative predictive value of 58.8% (p= 0.002, CI=95%) with 89.5 % accuracy. Conclusion: Platelet count to splenic bipolar diameter ratio can be a good predictor of presence of esophageal varices in patients with portal hypertension in the resource poor settings.

Development of the Cruveilhier-Baumgarten Syndrome after Endoscopic Obliteration of Oesophageal Varices

1989 ◽  
Vol 30 (4) ◽  
pp. 401-402 ◽  
Author(s):  
J. B. Dilawari ◽  
Y. K. Chawla ◽  
U. Kaur
Keyword(s):  
Liver Cirrhosis ◽  
Injection Sclerotherapy ◽  
Oesophageal Varices ◽  
Endoscopic Injection Sclerotherapy ◽  
Endoscopic Injection

A patient with post-necrotic liver cirrhosis, presenting with recurrent haematemesis and melena due to oesophageal varices, received repeated endoscopic injection sclerotherapy. The Cruveilhier-Baumgarten syndrome developed 11 months after variceal obliteration. Neither rebleeding nor recurrence of varices was observed during a follow up period of 12 months after obliteration of varices.

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