Lymphoblastoid interferon improves long-term response to a six month course of treatment when compared with recombinant interferon alpha 2b: Results of an international trial St. Louis U, U Sidney, Australia, Hospital Beaujon, Clichy, France, Virchow-Klinikum, Berlin, Hospital Ramon y Cajal, Madrid, Mt. Sinai Hospital, Toronto, Ospedale Molinette, Turin, Italy, UCSF, Burroughs Wellcome Co.

Hepatology ◽  
1995 ◽  
Vol 22 (4) ◽  
pp. A152 ◽  
Keyword(s):  
Interferon Alpha ◽  
Recombinant Interferon ◽  
International Trial ◽  
Interferon Alpha 2B ◽  
Term Response ◽  
Recombinant Interferon Alpha ◽  
Lymphoblastoid Interferon ◽  
Ramón Y Cajal

scholarly journals Long term follow-up and patterns of response of ALT in patients with chronic hepatitis NANB/C treated with recombinant interferon-alpha

1995 ◽  
Vol 37 (3) ◽  
pp. 239-243 ◽  
Author(s):  
L.C. da Silva ◽  
S.K. Ono ◽  
L.E.P. Fonseca ◽  
F.J. Carrilho ◽  
L.C.A. Mendes ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Interferon Alpha ◽  
Interferon Treatment ◽  
Recombinant Interferon ◽  
Long Term Follow Up ◽  
Ifn Treatment ◽  
Term Response ◽  
Recombinant Interferon Alpha

The response to interferon treatment in chronic hepatitis NANB/C has usually been classified as complete, partial or absent, according to the behavior of serum alanine aminotransferase (ALT). However, a more detailed observation of the enzymatic activity has shown that the patterns may be more complex. The aim of this study was to describe the long term follow-up and patterns of ALT response in patients with chronic hepatitis NANB/C treated with recombinant interferon-alpha. A follow-up of 6 months or more after interferon-a was achieved in 44 patients. We have classified the serum ALT responses into six patterns and the observed frequencies were as follows: I. Long term response = 9 (20.5%); II. Normalization followed by persistent relapse after IFN = 7 (15.9%); III. Normalization with transient relapse = 5 (11.9%); IV. Temporary normalization and relapse during IFN = 4 (9.1%); V. Partial response (more than 50% of ALT decrease) = 7 (15.9%); VI. No response = 12 (27.3%). In conclusion, ALT patterns vary widely during and after IFN treatment and can be classified in at least 6 types.

The use of combined recombinant interferon alpha-2b medications in the treatment of allergic rhinitis

Vrach ◽  
2021 ◽  
Vol 32 (3) ◽  
pp. 73-81
Author(s):  
D. Trukhan ◽  
V. Alekseenko ◽  
N. Kalashnikova ◽  
V. Minaeva ◽  
O. Shelyapina ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Interferon Alpha ◽  
Recombinant Interferon ◽  
Interferon Alpha 2B ◽  
Recombinant Interferon Alpha
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