Thermogenic capacity and brown adipose tissue activity in the common marmoset

1985 ◽  
Vol 81 (3) ◽  
pp. 683-686 ◽  
Author(s):  
Nancy J. Rothwell ◽  
Michael J. Stock
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Common Marmoset ◽  
Brown Adipose ◽  
The Common ◽  
Brown Adipose Tissue Activity ◽  
Thermogenic Capacity

Responses of brown adipose tissue activity to unloading in rats

1995 ◽  
Vol 78 (2) ◽  
pp. 384-387 ◽  
Author(s):  
H. Yamashita ◽  
Y. Ohira ◽  
T. Wakatsuki ◽  
M. Yamamoto ◽  
T. Kizaki ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Uncoupling Protein ◽  
Mitochondrial Fraction ◽  
Hindlimb Suspension ◽  
Chemical Components ◽  
Brown Adipose ◽  
Male Wistar Rats ◽  
Brown Adipose Tissue Activity ◽  
Thermogenic Capacity

To study the responses of thermogenic activity in brown adipose tissue (BAT) to unloading, male Wistar rats were hindlimb suspended for 10 days. Compared with control rats, a significant increase in the BAT-to-body mass ratio and considerable differences in chemical components in BAT were observed in the hindlimb-suspended rats. These findings indicate a marked increase in the thermogenic capacity in BAT of the experimental group. Likewise, the thermogenic activity (which was assessed by guanosine 5′-diphosphate binding to BAT mitochondria) was markedly greater in the mitochondria recovered from BAT of the hindlimb-suspended rats than in those from the control rats (1,610 +/- 450 vs. 202 +/- 132 pmol recovered). Moreover, the uncoupling protein content in the BAT mitochondrial fraction of the hindlimb-suspended rats was significantly higher (1.6-fold) than that in the control rats. As was expected, the uncoupling protein mRNA expression was greater in hindlimb-suspended rats than in control animals. These results suggest that chronic hindlimb suspension leads to an increase in both the thermogenic capacity and the activity in BAT of rats.

Short Dietary Intervention with Olive Oil Increases Brown Adipose Tissue Activity in Lean But Not Overweight/Obese Subjects

2020 ◽  
Author(s):  
Milena Monfort-Pires ◽  
Muuez U-Din ◽  
Guilherme A. Nogueira ◽  
Juliana de Almeida-Faria ◽  
Davi Sidarta-Oliveira ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Olive Oil ◽  
Dietary Intervention ◽  
Brown Adipose ◽  
Obese Subjects ◽  
Brown Adipose Tissue Activity

Reduced brown adipose tissue activity during cold exposure is a metabolic feature of the human thrifty phenotype

Metabolism ◽  
2021 ◽  
Vol 117 ◽  
pp. 154709 ◽  
Author(s):  
Tim Hollstein ◽  
Karyne Vinales ◽  
Kong Y. Chen ◽  
Aaron M. Cypess ◽  
Alessio Basolo ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cold Exposure ◽  
Thrifty Phenotype ◽  
Brown Adipose ◽  
Metabolic Feature ◽  
Brown Adipose Tissue Activity

scholarly journals Modulation of musculoskeletal hyperalgesia by brown adipose tissue activity in mice

Pain ◽  
2016 ◽  
Vol 157 (11) ◽  
pp. 2561-2570 ◽  
Author(s):  
Elizabeth M. Goudie-DeAngelis ◽  
Ramy E. Abdelhamid ◽  
Myra G. Nunez ◽  
Casey L. Kissel ◽  
Katalin J. Kovács ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Brown Adipose ◽  
Brown Adipose Tissue Activity

Brown adipose tissue metabolism in ob/ob mice: effects of a high-fat diet and adrenalectomy

1987 ◽  
Vol 253 (2) ◽  
pp. E149-E157
Author(s):  
H. K. Kim ◽  
D. R. Romsos
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
High Fat Diet ◽  
High Fat ◽  
Adipose Tissue Metabolism ◽  
High Carbohydrate ◽  
Bat Mitochondria ◽  
Norepinephrine Turnover ◽  
Brown Adipose ◽  
Thermogenic Capacity

Adrenalectomy prevents development of obesity in ob/ob mice fed high-carbohydrate stock diets partly by stimulating the low thermogenic capacity of their brown adipose tissue (BAT). Adrenalectomy, however, fails to prevent development of obesity in ob/ob mice fed a high-fat diet. Effects of adrenalectomy on BAT metabolism in ob/ob mice fed a high-fat diet were thus examined. ob/ob mice fed the high-fat diet developed gross obesity despite normal BAT metabolism, as assessed by rates of norepinephrine turnover in BAT, GDP binding to BAT mitochondria, and GDP-inhibitable, chloride-induced mitochondrial swelling. Adrenalectomy failed to arrest the development of obesity or to influence BAT metabolism in ob/ob mice fed the high-fat diet. Development of obesity in ob/ob mice fed a high-fat diet is not associated with low thermogenic capacity of BAT or with adrenal secretions, as it is in ob/ob mice fed high-carbohydrate stock diets.

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