Systematic generation of sequence-tagged sites for physical mapping of human chromosomes: Application to the mapping of human chromosome 7 using yeast artificial chromosomes

Genomics ◽  
1991 ◽  
Vol 11 (3) ◽  
pp. 548-564 ◽  
Author(s):  
Eric D. Green ◽  
Rose M. Mohr ◽  
Jacquelyn R. Idol ◽  
Myrna Jones ◽  
Judy M. Buckingham ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Physical Mapping ◽  
Chromosome 7 ◽  
Human Chromosomes ◽  
Artificial Chromosomes ◽  
Sequence Tagged Sites ◽  
Yeast Artificial Chromosomes ◽  
Human Chromosome 7

scholarly journals Establishment of Sequence-Tagged Sites on 15q11-q13 byAlu-Vector PCR Cloning of Yac-Generated Fragments

1996 ◽  
Vol 12 (4) ◽  
pp. 241-246
Author(s):  
W. S. Kim ◽  
Z. M. Deng ◽  
N. T. Nassif ◽  
A. Smith ◽  
R. J. Trent
Keyword(s):  
Human Chromosome ◽  
Angelman Syndrome ◽  
Chromosome 15 ◽  
Loss Of Function ◽  
Pcr Cloning ◽  
Artificial Chromosomes ◽  
Sequence Tagged Sites ◽  
Pcr Products ◽  
Yeast Artificial Chromosomes

Angelman syndrome (AS) is caused by the loss of function of undefined gene(s) on human chromosome 15. The majority of subjects have deletions involving maternally-derived chromosome 15q II-q 13, and the shortest region of deletion overlap (SRO) has been localized to the region between D15S10 and D15S113. In this study, yeast artificial chromosomes (YACs), 6G-D4, 9H-D2 and 37D-F9, mapping within the AS SRO, were isolated from the ICI Y AC library.Alu-vector PCR products were amplified from the YACs and from YACs A229A2 and A33FI 0 which had been obtained from the St. Louis Y AC library. The PCR products were cloned and sequenced, and three new sequence-tagged sites were generated within the AS SRO, facilitating the characterization of gene(s) involved in the Angelman syndrome.

Synteny mapping of five human chromosome 7 genes on bovine chromosomes 4 and 21

1999 ◽  
Vol 84 (1-2) ◽  
pp. 121-124
Author(s):  
E. Antoniou ◽  
J.E. Womack ◽  
M.D. Grosz
Keyword(s):  
Human Chromosome ◽  
Chromosome 7 ◽  
Human Chromosome 7 ◽  
Synteny Mapping

Construction and Characterization of a Partial Library of Yeast Artificial Chromosomes from Human Chromosome 21

1991 ◽  
Vol 10 (4) ◽  
pp. 301-310 ◽  
Author(s):  
M. BELLIS ◽  
A. GÉRARD ◽  
J.P. CHARLIEU ◽  
B. MARÇAIS ◽  
M.E. BRUN ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Artificial Chromosomes ◽  
Human Chromosome 21 ◽  
Yeast Artificial Chromosomes

Report of the First International Workshop on Human Chromosome 7 Mapping 1993

1994 ◽  
Vol 65 (1-2) ◽  
pp. 51-73 ◽  
Author(s):  
Karl-Heinz Grzeschik ◽  
Lap-Chee Tsui ◽  
Eric D. Green
Keyword(s):  
Human Chromosome ◽  
International Workshop ◽  
Chromosome 7 ◽  
Human Chromosome 7
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