The action of thallium on the excitability of CA1 pyramidal cells in hippocampal slices

1989 ◽  
Vol 11 (6) ◽  
pp. 545-549 ◽  
Author(s):  
H. Lohmann ◽  
M. Csicsaky ◽  
H. Wiegand
Keyword(s):  
Hippocampal Slices ◽  
Pyramidal Cells ◽  
Ca1 Pyramidal Cells

Network Interactions Mediated by New Excitatory Connections Between CA1 Pyramidal Cells in Rats With Kainate-Induced Epilepsy

2002 ◽  
Vol 87 (3) ◽  
pp. 1655-1658 ◽  
Author(s):  
Bret N. Smith ◽  
F. Edward Dudek
Keyword(s):  
Status Epilepticus ◽  
Action Potentials ◽  
Cell Layer ◽  
Hippocampal Slices ◽  
Pyramidal Cells ◽  
Ca1 Pyramidal Cells ◽  
Axon Sprouting ◽  
Synaptic Interactions ◽  
Network Bursts ◽  
Ca1 Area

Axon sprouting and synaptic reorganization in the hippocampus are associated with the development of seizures in temporal lobe epilepsy. Synaptic interactions among CA1 pyramidal cells were examined in fragments of hippocampal slices containing only the CA1 area from saline- and kainate-treated rats. Glutamate microapplication to the pyramidal cell layer increased excitatory postsynaptic current (EPSC) frequency, but only in rats with kainate-induced epilepsy. In bicuculline, action potentials evoked in single pyramidal cells increased the frequency of network bursts only in slices from rats with kainate-induced epilepsy. These data further support the hypothesis that excitatory connections between CA1 pyramidal cells increase after kainate-induced status epilepticus.

Coupling in rat hippocampal slices: Dye transfer between CA1 pyramidal cells

1982 ◽  
Vol 8 (2) ◽  
pp. 211-222 ◽  
Author(s):  
R.David Andrew ◽  
Charles P. Taylor ◽  
Robert W. Snow ◽  
F.Edward Dudek
Keyword(s):  
Hippocampal Slices ◽  
Pyramidal Cells ◽  
Dye Transfer ◽  
Ca1 Pyramidal Cells
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