A generalized analysis of internal diffusion of immobilized enzyme in multi-enzyme reactions

Author(s):  
Gloria Víllora Cano ◽  
Antonio López Cabanes
2004 ◽  
Vol 9 (2) ◽  
pp. 139-144 ◽  
Author(s):  
J. Kulys

A model of biosensor containing three immobilized enzymes utilizing consecutive substrate conversion in the chain was developed. The modeling was performed at an internal diffusion limitation and a steadystate condition. The calculations showed that significant response of biosensors was produced if diffusion modules were larger than 1 for all enzyme reactions. Due to diffusion limitation the apparent stability of biosensor response increased many times in comparison to stability of the most labile enzyme of the chain.


1987 ◽  
Vol 29 (8) ◽  
pp. 924-933 ◽  
Author(s):  
Haruo Ishikawa ◽  
Takenori Tanaka ◽  
Katsuo Kurose ◽  
Haruo Hikita

1996 ◽  
Vol 12 (1) ◽  
pp. 137-139 ◽  
Author(s):  
Hisakazu MORI ◽  
Mamie KOGURE ◽  
Hitoshi TAKEI ◽  
Haruhiko YAMAMOTO

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