P-216 Evaluation of energy metabolism related to bile formation in isolated perfused rat liver using 31P-NMR spectroscopy

1995 ◽  
Vol 3 ◽  
pp. S90
Author(s):  
T NAKASHIMA
1964 ◽  
Vol 207 (5) ◽  
pp. 1030-1034 ◽  
Author(s):  
G. F. Leong ◽  
D. M. Cazes ◽  
M. L. Berliner ◽  
D. L. Berliner

The rates of biliary excretion of dihydro-11-keto-progesterone-4-C14 and of its metabolites were studied in the isolated perfused rat liver. The half-life of this steroid in the perfusing blood was 2.5 min, and at 40 min about 75% of the injected steroid had been excreted in bile. Formation of water-soluble steroids (WS St) took place at a rapid rate and by 60 min 100% of the steroids in blood were found to be water soluble. During the entire study the steroids excreted in bile were water soluble and accounted for 97.2–100% (avg. 98.2%). No dihydro-11-keto-progesterone was found to be excreted in the bile. The rate of disappearance from the blood, excretion in the bile, and degree of formation of WS St of this compound when compared with corticosterone and cortisol shows the following pattern: dihydro-11-keto-progesterone > corticosterone > cortisol.


Life Sciences ◽  
1991 ◽  
Vol 49 (7) ◽  
pp. 511-518 ◽  
Author(s):  
Toshiyuki Kitai ◽  
Akira Tanaka ◽  
Mitsuhiro Terasaki ◽  
Ryoji Okamoto ◽  
Kazue Ozawa ◽  
...  

2010 ◽  
Vol 101 (2) ◽  
pp. 113-118 ◽  
Author(s):  
Françoise Miot ◽  
Marc van Cauteren ◽  
A. Katelijne Rooze ◽  
Albert Geerts ◽  
Michel Osteaux ◽  
...  

1974 ◽  
Vol 285 (2) ◽  
pp. 165-174 ◽  
Author(s):  
G. Paumgartner ◽  
R. Herz ◽  
K. Sauter ◽  
H. P. Schwarz

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